| Evolution and impact of subclonal mutations in chronic lymphocytic leukemia DA Landau, SL Carter, P Stojanov, A McKenna, K Stevenson, ... Cell 152 (4), 714-726, 2013 | 1611 | 2013 |
| SF3B1 and other novel cancer genes in chronic lymphocytic leukemia L Wang, MS Lawrence, Y Wan, P Stojanov, C Sougnez, K Stevenson, ... New England Journal of Medicine 365 (26), 2497-2506, 2011 | 1382 | 2011 |
| Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia DA Landau, K Clement, MJ Ziller, P Boyle, J Fan, H Gu, K Stevenson, ... Cancer cell 26 (6), 813-825, 2014 | 378 | 2014 |
| Physiologic expression of Sf3b1K700E causes impaired erythropoiesis, aberrant splicing, and sensitivity to therapeutic spliceosome modulation EA Obeng, RJ Chappell, M Seiler, MC Chen, DR Campagna, PJ Schmidt, ... Cancer cell 30 (3), 404-417, 2016 | 374 | 2016 |
| Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition JA Burger, DA Landau, A Taylor-Weiner, I Bozic, H Zhang, K Sarosiek, ... Nature communications 7 (1), 11589, 2016 | 370 | 2016 |
| SS synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase R Wuerffel, L Wang, F Grigera, J Manis, E Selsing, T Perlot, FW Alt, ... Immunity 27 (5), 711-722, 2007 | 234 | 2007 |
| Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia F Gaiti, R Chaligne, H Gu, RM Brand, S Kothen-Hill, RC Schulman, ... Nature 569 (7757), 576-580, 2019 | 219 | 2019 |
| Transcriptomic characterization of SF3B1 mutation reveals its pleiotropic effects in chronic lymphocytic leukemia L Wang, AN Brooks, J Fan, Y Wan, R Gambe, S Li, S Hergert, S Yin, ... Cancer cell 30 (5), 750-763, 2016 | 210 | 2016 |
| Nanowire-mediated delivery enables functional interrogation of primary immune cells: application to the analysis of chronic lymphocytic leukemia AK Shalek, JT Gaublomme, L Wang, N Yosef, N Chevrier, MS Andersen, ... Nano letters 12 (12), 6498-6504, 2012 | 200 | 2012 |
| S region sequence, RNA polymerase II, and histone modifications create chromatin accessibility during class switch recombination L Wang, R Wuerffel, S Feldman, AA Khamlichi, AL Kenter Journal of Experimental Medicine 206 (8), 1817-1830, 2009 | 158 | 2009 |
| Decreased mitochondrial apoptotic priming underlies stroma-mediated treatment resistance in chronic lymphocytic leukemia MS Davids, J Deng, A Wiestner, BJ Lannutti, L Wang, CJ Wu, WH Wilson, ... Blood, The Journal of the American Society of Hematology 120 (17), 3501-3509, 2012 | 130 | 2012 |
| Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL L Wang, AK Shalek, M Lawrence, R Ding, JT Gaublomme, N Pochet, ... Blood, The Journal of the American Society of Hematology 124 (7), 1089-1098, 2014 | 97 | 2014 |
| AID-dependent histone acetylation is detected in immunoglobulin S regions L Wang, N Whang, R Wuerffel, AL Kenter The Journal of experimental medicine 203 (1), 215-226, 2006 | 95 | 2006 |
| A murine model of chronic lymphocytic leukemia based on B cell-restricted expression of Sf3b1 mutation and Atm deletion S Yin, RG Gambe, J Sun, AZ Martinez, ZJ Cartun, FFD Regis, Y Wan, ... Cancer Cell 35 (2), 283-296. e5, 2019 | 93 | 2019 |
| Integrated single-cell genetic and transcriptional analysis suggests novel drivers of chronic lymphocytic leukemia L Wang, J Fan, JM Francis, G Georghiou, S Hergert, S Li, R Gambe, ... Genome research 27 (8), 1300-1311, 2017 | 84 | 2017 |
| Genomic and transcriptomic profiling reveals distinct molecular subsets associated with outcomes in mantle cell lymphoma S Yi, Y Yan, M Jin, S Bhattacharya, Y Wang, Y Wu, L Yang, E Gine, G Clot, ... The Journal of clinical investigation 132 (3), 2022 | 48 | 2022 |
| Three‐dimensional architecture of the IgH locus facilitates class switch recombination AL Kenter, S Feldman, R Wuerffel, I Achour, L Wang, S Kumar Annals of the New York Academy of Sciences 1267 (1), 86-94, 2012 | 47 | 2012 |
| Splicing modulation sensitizes chronic lymphocytic leukemia cells to venetoclax by remodeling mitochondrial apoptotic dependencies E Ten Hacken, R Valentin, FFD Regis, J Sun, S Yin, L Werner, J Deng, ... JCI insight 3 (19), 2018 | 46 | 2018 |
| Expression of AID transgene is regulated in activated B cells but not in resting B cells and kidney HM Shen, G Bozek, CA Pinkert, K McBride, L Wang, A Kenter, U Storb Molecular immunology 45 (7), 1883-1892, 2008 | 38 | 2008 |
| A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation G Lazarian, S Yin, E Ten Hacken, T Sewastianik, M Uduman, A Font-Tello, ... Cancer Cell 39 (3), 380-393. e8, 2021 | 37 | 2021 |
