The stop-and-go traffic regulating protein biogenesis: How translation kinetics controls proteostasis KC Stein, J Frydman Journal of Biological Chemistry 294 (6), 2076-2084, 2019 | 132 | 2019 |
Ageing exacerbates ribosome pausing to disrupt cotranslational proteostasis KC Stein, F Morales-Polanco, J van der Lienden, TK Rainbolt, J Frydman Nature 601 (7894), 637-642, 2022 | 102 | 2022 |
Nascent polypeptide domain topology and elongation rate direct the cotranslational hierarchy of Hsp70 and TRiC/CCT KC Stein, A Kriel, J Frydman Molecular cell 75 (6), 1117-1130. e5, 2019 | 91 | 2019 |
Myopathy-causing mutations in an HSP40 chaperone disrupt processing of specific client conformers KC Stein, R Bengoechea, MB Harms, CC Weihl, HL True Journal of Biological Chemistry 289 (30), 21120-21130, 2014 | 61 | 2014 |
Selective sweeps and parallel mutation in the adaptive recovery from deleterious mutation in Caenorhabditis elegans DR Denver, DK Howe, LJ Wilhelm, CA Palmer, JL Anderson, KC Stein, ... Genome research 20 (12), 1663-1671, 2010 | 49 | 2010 |
Extensive diversity of prion strains is defined by differential chaperone interactions and distinct amyloidogenic regions KC Stein, HL True PLoS genetics 10 (5), e1004337, 2014 | 42 | 2014 |
Spontaneous variants of the [RNQ+] prion in yeast demonstrate the extensive conformational diversity possible with prion proteins VJ Huang, KC Stein, HL True PloS one 8 (10), e79582, 2013 | 39 | 2013 |
Structural variants of yeast prions show conformer‐specific requirements for chaperone activity KC Stein, HL True Molecular microbiology 93 (6), 1156-1171, 2014 | 38 | 2014 |
Natural variation in life history and aging phenotypes is associated with mitochondrial DNA deletion frequency in Caenorhabditis briggsae S Estes, AL Coleman-Hulbert, KA Hicks, G de Haan, SR Martha, ... BMC evolutionary biology 11, 1-8, 2011 | 33 | 2011 |
Heterologous prion-forming proteins interact to cross-seed aggregation in Saccharomyces cerevisiae KM Keefer, KC Stein, HL True Scientific reports 7 (1), 5853, 2017 | 31 | 2017 |
The [RNQ+] prion: A model of both functional and pathological amyloid KC Stein, HL True Prion 5 (4), 291-298, 2011 | 31 | 2011 |
Inhibition of DNAJ-HSP70 interaction improves strength in muscular dystrophy R Bengoechea, AR Findlay, AK Bhadra, H Shao, KC Stein, SK Pittman, ... The Journal of clinical investigation 130 (8), 4470-4485, 2020 | 29 | 2020 |
Prion strains and amyloid polymorphism influence phenotypic variation KC Stein, HL True PLoS pathogens 10 (9), e1004328, 2014 | 28 | 2014 |
Regulation of the Hsp104 middle domain activity is critical for yeast prion propagation JE Dulle, KC Stein, HL True PloS one 9 (1), e87521, 2014 | 26 | 2014 |
The unfolded protein response of the endoplasmic reticulum supports mitochondrial biogenesis by buffering nonimported proteins K Knöringer, C Groh, L Krämer, KC Stein, KG Hansen, J Zimmermann, ... Molecular biology of the cell 34 (10), ar95, 2023 | 7 | 2023 |
Close and Careful but not Cautious: Using the Writer’s Workshop Method in the Reading Classroom K Stein, O Wilde The Journal of Literature in Language Teaching 3 (1), 34-41, 2014 | 2 | 2014 |
Pictogloss: a student-driven process of activity development K STEIN ETAS Journal 30 (1), 24-26, 2012 | 1 | 2012 |
Prion Strains and Amyloid Polymorphism KC Stein, HL True | | 2014 |
P. 5.11 LGMD1D mutations in DNAJB6 disrupt disaggregation of TDP-43 R Bengoechea, EP Tuck, KC Stein, SK Pittman, RH Baloh, HL True, ... Neuromuscular Disorders 23 (9), 767, 2013 | | 2013 |