| Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression L Chen, DL Gibbons, S Goswami, MA Cortez, YH Ahn, LA Byers, X Zhang, ... Nature Communications 5, 5241-5252, 2014 | 917 | 2014 |
| Targeting DNA damage response promotes antitumor immunity through STING-mediated T-cell activation in small cell lung cancer T Sen, BL Rodriguez, L Chen, CMD Corte, N Morikawa, J Fujimoto, ... Cancer discovery 9 (5), 646-661, 2019 | 631 | 2019 |
| Epithelial–mesenchymal transition is associated with a distinct tumor microenvironment including elevation of inflammatory signals and multiple immune checkpoints in lung … Y Lou, L Diao, ERP Cuentas, WL Denning, L Chen, YH Fan, LA Byers, ... Clinical Cancer Research 22 (14), 3630-3642, 2016 | 394 | 2016 |
| CD38-mediated immunosuppression as a mechanism of tumor cell escape from PD-1/PD-L1 blockade L Chen, L Diao, Y Yang, X Yi, BL Rodriguez, Y Li, PA Villalobos, ... Cancer discovery 8 (9), 1156-1175, 2018 | 368 | 2018 |
| Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8+ T cell exhaustion DH Peng, BL Rodriguez, L Diao, L Chen, J Wang, LA Byers, Y Wei, ... Nature communications 11 (1), 4520, 2020 | 240 | 2020 |
| Chemical genetics identify eIF2α kinase heme-regulated inhibitor as an anticancer target T Chen, D Ozel, Y Qiao, F Harbinski, L Chen, S Denoyelle, X He, ... Nature chemical biology 7 (9), 610-616, 2011 | 135 | 2011 |
| Tumor suppression by small molecule inhibitors of translation initiation L Chen, BH Aktas, Y Wang, X He, R Sahoo, N Zhang, S Denoyelle, ... Oncotarget 3 (8), 869-881, 2012 | 112 | 2012 |
| Twist induces epithelial-mesenchymal transition in cervical carcinogenesis by regulating the TGF-β/Smad3 signaling pathway Q Fan, MT Qiu, Z Zhu, JH Zhou, L Chen, Y Zhou, W Gu, LH Wang, ZN Li, ... Oncology reports 34 (4), 1787-1794, 2015 | 63 | 2015 |
| In vitro inhibition of translation initiation by N, N′-diarylureas—potential anti-cancer agents S Denoyelle, T Chen, L Chen, Y Wang, E Klosi, JA Halperin, BH Aktas, ... Bioorganic & medicinal chemistry letters 22 (1), 402-409, 2012 | 60 | 2012 |
| Th17 cells contribute to combination MEK inhibitor and anti-PD-L1 therapy resistance in KRAS/p53 mutant lung cancers DH Peng, BL Rodriguez, L Diao, PO Gaudreau, A Padhye, JM Konen, ... Nature communications 12 (1), 2606, 2021 | 48 | 2021 |
| An essential role for platelet-activating factor in activating mast cell migration following ultraviolet irradiation R Chacón-Salinas, L Chen, AD Chávez-Blanco, AY Limón-Flores, Y Ma, ... Journal of Leukocyte Biology 95 (1), 139-148, 2014 | 48 | 2014 |
| Reversal of the phenotype by K-rasval12 silencing mediated by adenovirus-delivered siRNA in human pancreatic cancer cell line Panc-1 L Chen, HY Le, RY Qin, M Kumar, ZY Du, RJ Xia, J Deng World journal of gastroenterology: WJG 11 (6), 831-838, 2005 | 47 | 2005 |
| Overexpression of CXC chemokine ligand 14 exacerbates collagen-induced arthritis L Chen, L Guo, J Tian, H He, E Marinova, P Zhang, B Zheng, S Han The Journal of Immunology 184 (8), 4455-4459, 2010 | 41 | 2010 |
| KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1 MT Qiu, Q Fan, Z Zhu, SY Kwan, L Chen, JH Chen, ZL Ying, Y Zhou, W Gu, ... Oncotarget 6 (31), 31702, 2015 | 37 | 2015 |
| Deficiency in activation-induced cytidine deaminase promotes systemic autoimmunity in lpr mice on a C57BL/6 background L Chen, L Guo, J Tian, B Zheng, S Han Clinical & Experimental Immunology 159 (2), 169-175, 2010 | 31 | 2010 |
| The mutually regulatory loop of epithelial–mesenchymal transition and immunosuppression in cancer progression L Chen, JV Heymach, FXF Qin, DL Gibbons Oncoimmunology 4 (5), e1002731, 2015 | 30 | 2015 |
| Synthesis of rigidified eIF4E/eIF4G inhibitor-1 (4EGI-1) mimetic and their in vitro characterization as inhibitors of protein–protein interaction P Mahalingam, K Takrouri, T Chen, R Sahoo, E Papadopoulos, L Chen, ... Journal of medicinal chemistry 57 (12), 5094-5111, 2014 | 29 | 2014 |
| Amplification and functional characterization of MUC1 promoter and gene-virotherapy via a targeting adenoviral vector expressing hSSTR2 gene in MUC1-positive Panc-1 pancreatic … L Chen, Q Liu, R Qin, H Le, R Xia, W Li, M Kumar International journal of molecular medicine 15 (4), 617-626, 2005 | 27 | 2005 |
| Growth and metastasis of lung adenocarcinoma is potentiated by BMP4-mediated immunosuppression L Chen, X Yi, S Goswami, YH Ahn, JD Roybal, Y Yang, L Diao, D Peng, ... Oncoimmunology 5 (11), e1234570, 2016 | 25 | 2016 |
| γ-Glutamyl cyclotransferase contributes to tumor progression in high grade serous ovarian cancer by regulating epithelial-mesenchymal transition via activating PI3K/AKT/mTOR … Y Li, T Wu, Y Wang, L Yang, C Hu, L Chen, S Wu Gynecologic oncology 149 (1), 163-172, 2018 | 24 | 2018 |
