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Parinati Kharel
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Mechanism-based rescue of Munc18-1 dysfunction in varied encephalopathies by chemical chaperones
NGL Guiberson, A Pineda, D Abramov, P Kharel, KE Carnazza, RT Wragg, ...
Nature communications 9 (1), 3986, 2018
732018
Lysosomal exocytosis releases pathogenic α-synuclein species from neurons in synucleinopathy models
YX Xie, NN Naseri, J Fels, P Kharel, Y Na, D Lane, J Burré, M Sharma
Nature communications 13 (1), 4918, 2022
302022
Aggregation of mutant cysteine string protein-α via Fe–S cluster binding is mitigated by iron chelators
NN Naseri, B Ergel, P Kharel, Y Na, Q Huang, R Huang, N Dolzhanskaya, ...
Nature structural & molecular biology 27 (2), 192-201, 2020
192020
The presence of the ACA box in archaeal H/ACA guide RNAs promotes atypical pseudouridylation
M Majumder, S Mukhopadhyay, P Kharel, R Gupta
RNA 26 (4), 396-418, 2020
62020
Lysosomal Exocytosis Releases Pathogenic α-Synuclein Species from Neurons
YX Xie, NN Naseri, J Fels, P Kharel, Y Na, J Burré, M Sharma
BioRxiv, 2021.04. 10.439302, 2021
32021
Molecular mechanisms underlying STXBP1/MUNC18-1 linked encephalopathies and rational rescue strategies
J Burre, NGL Guiberson, A Pineda, D Abramov, P Kharel, KE Carnazza, ...
JOURNAL OF NEUROCHEMISTRY 150, 15-15, 2019
2019
Structural and functional characterization of archaeal fibrillarin (c/d box protein) in vivo
P Kharel
Southern Illinois University at Carbondale, 2013
2013
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Articles 1–7