| Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis S Yousefi, R Perozzo, I Schmid, A Ziemiecki, T Schaffner, L Scapozza, ... Nature cell biology 8 (10), 1124-1132, 2006 | 1513 | 2006 |
| Thermodynamics of protein–ligand interactions: history, presence, and future aspects R Perozzo, G Folkers, L Scapozza Journal of Receptors and Signal Transduction 24 (1-2), 1-52, 2004 | 530 | 2004 |
| Molecular mechanisms of resistance to imatinib in Philadelphia-chromosome-positive leukaemias CB Gambacorti-Passerini, RH Gunby, R Piazza, A Galietta, R Rostagno, ... The lancet oncology 4 (2), 75-85, 2003 | 510 | 2003 |
| In vitro and in vivo activity of SKI-606, a novel Src-Abl inhibitor, against imatinib-resistant Bcr-Abl+ neoplastic cells M Puttini, AML Coluccia, F Boschelli, L Cleris, E Marchesi, ... Cancer research 66 (23), 11314-11322, 2006 | 468 | 2006 |
| Directed evolution of thymidine kinase for AZT phosphorylation using DNA family shuffling FC Christians, L Scapozza, A Crameri, G Folkers, WPC Stemmer Nature biotechnology 17 (3), 259-264, 1999 | 433 | 1999 |
| Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation S Conus, R Perozzo, T Reinheckel, C Peters, L Scapozza, S Yousefi, ... The Journal of experimental medicine 205 (3), 685-698, 2008 | 319 | 2008 |
| Mammalian RAD52 functions in break-induced replication repair of collapsed DNA replication forks SK Sotiriou, I Kamileri, N Lugli, K Evangelou, C Da-Ré, F Huber, ... Molecular cell 64 (6), 1127-1134, 2016 | 283 | 2016 |
| Small-molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets V Jaquet, L Scapozza, RA Clark, KH Krause, JD Lambeth Antioxidants & redox signaling 11 (10), 2535-2552, 2009 | 281 | 2009 |
| Inhibition of Plasmodium falciparum Fatty Acid Biosynthesis: Evaluation of FabG, FabZ, and FabI as Drug Targets for Flavonoids D Tasdemir, G Lack, R Brun, P Rüedi, L Scapozza, R Perozzo Journal of medicinal chemistry 49 (11), 3345-3353, 2006 | 227 | 2006 |
| Single-molecule pulling simulations can discern active from inactive enzyme inhibitors F Colizzi, R Perozzo, L Scapozza, M Recanatini, A Cavalli Journal of the American Chemical Society 132 (21), 7361-7371, 2010 | 203 | 2010 |
| Batimastat, a potent matrix mealloproteinase inhibitor, exhibits an unexpected mode of binding. I Botos, L Scapozza, D Zhang, LA Liotta, EF Meyer Proceedings of the National Academy of Sciences 93 (7), 2749-2754, 1996 | 189 | 1996 |
| Drug repurposing in oncology: Compounds, pathways, phenotypes and computational approaches for colorectal cancer P Nowak-Sliwinska, L Scapozza, AR i Altaba Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1871 (2), 434-454, 2019 | 173 | 2019 |
| Tautomerism in computer‐aided drug design P Pospisil, P Ballmer, L Scapozza, G Folkers Journal of Receptors and Signal Transduction 23 (4), 361-371, 2003 | 156 | 2003 |
| NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action V Jaquet, J Marcoux, E Forest, KG Leidal, S McCormick, Y Westermaier, ... British journal of pharmacology 164 (2b), 507-520, 2011 | 144 | 2011 |
| The periplasmic domain of the histidine autokinase CitA functions as a highly specific citrate receptor S Kaspar, R Perozzo, S Reinelt, M Meyer, K Pfister, L Scapozza, M Bott Molecular microbiology 33 (4), 858-872, 1999 | 130 | 1999 |
| Molecular dynamics simulation of MHC-peptide complexes as a tool for predicting potential T cell epitopes D Rognan, L Scapozza, G Folkers, A Daser Biochemistry 33 (38), 11476-11485, 1994 | 121 | 1994 |
| The different flexibility of c-Src and c-Abl kinases regulates the accessibility of a druggable inactive conformation S Lovera, L Sutto, R Boubeva, L Scapozza, N Dölker, FL Gervasio Journal of the American Chemical Society 134 (5), 2496-2499, 2012 | 119 | 2012 |
| Substrate diversity of herpes simplex virus thymidine kinase: impact of the kinematics of the enzyme BD Pilger, R Perozzo, F Alber, C Wurth, G Folkers, L Scapozza Journal of Biological Chemistry 274 (45), 31967-31973, 1999 | 112 | 1999 |
| Synthesis and in vitro characterization of organometallic rhenium and technetium glucose complexes against glut 1 and hexokinase R Schibli, C Dumas, J Petrig, L Spadola, L Scapozza, E Garcia-Garayoa, ... Bioconjugate chemistry 16 (1), 105-112, 2005 | 110 | 2005 |
| Cross-reactivity and 1.4-A crystal structure of Malassezia sympodialis thioredoxin (Mala s 13), a member of a new pan-allergen family A Limacher, AG Glaser, C Meier, P Schmid-Grendelmeier, S Zeller, ... The Journal of Immunology 178 (1), 389-396, 2007 | 105 | 2007 |
