Activation of a HIF1α-PPARγ axis underlies the integration of glycolytic and lipid anabolic pathways in pathologic cardiac hypertrophy J Krishnan, M Suter, R Windak, T Krebs, A Felley, C Montessuit, ... Cell metabolism 9 (6), 512-524, 2009 | 406 | 2009 |
Age-dependent changes in metabolism, contractile function, and ischemic sensitivity in hearts from db/db mice E Aasum, AD Hafstad, DL Severson, TS Larsen Diabetes 52 (2), 434-441, 2003 | 368 | 2003 |
Increased myocardial oxygen consumption reduces cardiac efficiency in diabetic mice OJ How, E Aasum, DL Severson, WYA Chan, MF Essop, TS Larsen Diabetes 55 (2), 466-473, 2006 | 316 | 2006 |
Interval Training Normalizes Cardiomyocyte Function, Diastolic Ca2+ Control, and SR Ca2+ Release Synchronicity in a Mouse Model of Diabetic Cardiomyopathy TO Stølen, MA Høydal, OJ Kemi, D Catalucci, M Ceci, E Aasum, T Larsen, ... Circulation research 105 (6), 527-536, 2009 | 259 | 2009 |
High-and moderate-intensity training normalizes ventricular function and mechanoenergetics in mice with diet-induced obesity AD Hafstad, J Lund, E Hadler-Olsen, AC Höper, TS Larsen, E Aasum Diabetes 62 (7), 2287-2294, 2013 | 252 | 2013 |
Cardiac function and metabolism in type 2 diabetic mice after treatment with BM 17.0744, a novel PPAR-α activator E Aasum, DD Belke, DL Severson, RA Riemersma, M Cooper, ... American Journal of Physiology-Heart and Circulatory Physiology 283 (3 …, 2002 | 210 | 2002 |
Glucose-insulin-potassium reduces infarct size when administered during reperfusion AK Jonassen, E Aasum, RA Riemersma, OD Mjøs, TS Larsen Cardiovascular drugs and therapy 14, 615-623, 2000 | 183 | 2000 |
How exercise may amend metabolic disturbances in diabetic cardiomyopathy AD Hafstad, N Boardman, E Aasum Antioxidants & redox signaling 22 (17), 1587-1605, 2015 | 158 | 2015 |
High intensity interval training alters substrate utilization and reduces oxygen consumption in the heart AD Hafstad, NT Boardman, J Lund, M Hagve, AM Khalid, U Wisløff, ... Journal of Applied Physiology 111 (5), 1235-1241, 2011 | 153 | 2011 |
Influence of substrate supply on cardiac efficiency, as measured by pressure-volume analysis in ex vivo mouse hearts OJ How, E Aasum, S Kunnathu, DL Severson, ESP Myhre, TS Larsen American Journal of Physiology-Heart and Circulatory Physiology 288 (6 …, 2005 | 135 | 2005 |
Treatment of type 2 diabetic db/db mice with a novel PPARγ agonist improves cardiac metabolism but not contractile function AN Carley, LM Semeniuk, Y Shimoni, E Aasum, TS Larsen, JP Berger, ... American Journal of Physiology-Endocrinology and Metabolism 286 (3), E449-E455, 2004 | 125 | 2004 |
Glucose and insulin improve cardiac efficiency and postischemic functional recovery in perfused hearts from type 2 diabetic (db/db) mice AD Hafstad, AM Khalid, OJ How, TS Larsen, E Aasum American Journal of Physiology-Endocrinology and Metabolism 292 (5), E1288-E1294, 2007 | 95 | 2007 |
Perfused hearts from Type 2 diabetic (db/db) mice show metabolic responsiveness to insulin AD Hafstad, GH Solevåg, DL Severson, TS Larsen, E Aasum American Journal of Physiology-Heart and Circulatory Physiology 290 (5 …, 2006 | 88 | 2006 |
The role of NADPH oxidases in diabetic cardiomyopathy SS Hansen, E Aasum, AD Hafstad Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (5 …, 2018 | 77 | 2018 |
Cardiac peroxisome proliferator-activated receptor-α activation causes increased fatty acid oxidation, reducing efficiency and post-ischaemic functional loss AD Hafstad, AM Khalid, M Hagve, T Lund, TS Larsen, DL Severson, ... Cardiovascular research 83 (3), 519-526, 2009 | 76 | 2009 |
Fenofibrate modulates cardiac and hepatic metabolism and increases ischemic tolerance in diet-induced obese mice E Aasum, AM Khalid, OA Gudbrandsen, OJ How, RK Berge, TS Larsen Journal of molecular and cellular cardiology 44 (1), 201-209, 2008 | 73 | 2008 |
Myosin activator omecamtiv mecarbil increases myocardial oxygen consumption and impairs cardiac efficiency mediated by resting myosin ATPase activity JP Bakkehaug, AB Kildal, ET Engstad, N Boardman, T Næsheim, ... Circulation: Heart Failure 8 (4), 766-775, 2015 | 71 | 2015 |
Overexpression of angiotensinogen in the myocardium induces downregulation of the fatty acid oxidation pathway C Pellieux, E Aasum, TS Larsen, C Montessuit, I Papageorgiou, ... Journal of molecular and cellular cardiology 41 (3), 459-466, 2006 | 70 | 2006 |
On the pivotal role of PPARα in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury MA Cole, AH Abd Jamil, LC Heather, AJ Murray, ER Sutton, M Slingo, ... The faseb journal 30 (8), 2684, 2016 | 69 | 2016 |
Cardiac metabolism in mice: tracer method developments and in vivo application revealing profound metabolic inflexibility in diabetes ND Oakes, P Thalén, E Aasum, A Edgley, T Larsen, SM Furler, B Ljung, ... American Journal of Physiology-Endocrinology and Metabolism 290 (5), E870-E881, 2006 | 69 | 2006 |