| Restriction of the conformational dynamics of the cyclic acyldepsipeptide antibiotics improves their antibacterial activity DW Carney, KR Schmitz, JV Truong, RT Sauer, JK Sello Journal of the American Chemical Society 136 (5), 1922-1929, 2014 | 114 | 2014 |
| Crystal structure of Mycobacterium tuberculosis ClpP1P2 suggests a model for peptidase activation by AAA+ partner binding and substrate delivery KR Schmitz, DW Carney, JK Sello, RT Sauer Proceedings of the National Academy of Sciences 111 (43), E4587-E4595, 2014 | 102 | 2014 |
| A retrograde trafficking inhibitor of ricin and Shiga-like toxins inhibits infection of cells by human and monkey polyomaviruses CDS Nelson, DW Carney, A Derdowski, A Lipovsky, GV Gee, B O’Hara, ... MBio 4 (6), 10.1128/mbio. 00729-13, 2013 | 74 | 2013 |
| A simple fragment of cyclic acyldepsipeptides is necessary and sufficient for ClpP activation and antibacterial activity DW Carney, CL Compton, KR Schmitz, JP Stevens, RT Sauer, JK Sello ChemBioChem 15 (15), 2216-2220, 2014 | 44 | 2014 |
| Structural optimization of a retrograde trafficking inhibitor that protects cells from infections by human polyoma-and papillomaviruses DW Carney, CDS Nelson, BD Ferris, JP Stevens, A Lipovsky, T Kazakov, ... Bioorganic & medicinal chemistry 22 (17), 4836-4847, 2014 | 43 | 2014 |
| A porphyrin molecule that generates, traps, stores, and releases singlet oxygen C Changtong, DW Carney, L Luo, CA Zoto, JL Lombardi, RE Connors Journal of Photochemistry and Photobiology A: Chemistry 260, 9-13, 2013 | 39 | 2013 |
| Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors COVID Moonshot Consortium, H Achdout, A Aimon, DS Alonzi, R Arbon, ... BioRxiv, 2020.10. 29.339317, 2020 | 36 | 2020 |
| Investigation of the configurational stabilities of chiral isocyanoacetates in multicomponent reactions DW Carney, JV Truong, JK Sello The Journal of Organic Chemistry 76 (24), 10279-10285, 2011 | 36 | 2011 |
| Synthetic approaches to the new drugs approved during 2019 AC Flick, CA Leverett, HX Ding, E McInturff, SJ Fink, S Mahapatra, ... Journal of Medicinal Chemistry 64 (7), 3604-3657, 2021 | 33 | 2021 |
| Ultrapotent vinblastines in which added molecular complexity further disrupts the target tubulin dimer–dimer interface DW Carney, JC Lukesh III, DM Brody, MM Brütsch, DL Boger Proceedings of the National Academy of Sciences 113 (35), 9691-9698, 2016 | 30 | 2016 |
| Continuous-flow chemistry in undergraduate education: sustainable conversion of reclaimed vegetable oil into biodiesel FA Leibfarth, MG Russell, DM Langley, H Seo, LP Kelly, DW Carney, ... Journal of Chemical Education 95 (8), 1371-1375, 2018 | 29 | 2018 |
| Dissecting the binding interactions of teixobactin with the bacterial cell‐wall precursor lipid II S Chiorean, I Antwi, DW Carney, I Kotsogianni, AM Giltrap, FM Alexander, ... ChemBioChem 21 (6), 789-792, 2020 | 27 | 2020 |
| Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors ML Boby, D Fearon, M Ferla, M Filep, L Koekemoer, MC Robinson, ... Science 382 (6671), eabo7201, 2023 | 25 | 2023 |
| A Conformationally Constrained Cyclic Acyldepsipeptide Is Highly Effective in Mice Infected with Methicillin-Susceptible and -Resistant Staphylococcus aureus M Arvanitis, G Li, DD Li, D Cotnoir, L Ganley-Leal, DW Carney, JK Sello, ... PLoS One 11 (4), e0153912, 2016 | 20 | 2016 |
| Synthetic approaches to the new drugs approved during 2020 AC Flick, CA Leverett, HX Ding, EL McInturff, SJ Fink, S Mahapatra, ... Journal of Medicinal Chemistry 65 (14), 9607-9661, 2022 | 19 | 2022 |
| Vinblastine 20′ amides: synthetic analogues that maintain or improve potency and simultaneously overcome Pgp-derived efflux and resistance JC Lukesh III, DW Carney, H Dong, RM Cross, V Shukla, KK Duncan, ... Journal of medicinal chemistry 60 (17), 7591-7604, 2017 | 19 | 2017 |
| Fragment-based strategy for investigating and suppressing the efflux of bioactive small molecules CL Compton, DW Carney, PV Groomes, JK Sello ACS infectious diseases 1 (1), 53-58, 2015 | 12 | 2015 |
| Examination of a structural model of peptidomimicry by cyclic acyldepsipeptide antibiotics in their interaction with the ClpP peptidase DW Carney, KR Schmitz, AC Scruse, RT Sauer, JK Sello ChemBioChem 16 (13), 1875-1879, 2015 | 8 | 2015 |
| A retrograde trafficking inhibitor of ricin and Shiga-like toxins inhibits infection of cells by human and monkey polyomaviruses. MBio. 2013; 4 (6): e00729–13 CD Nelson, DW Carney, A Derdowski, A Lipovsky, GV Gee, B O’Hara, ... No. e00729–13.[Europe PMC free article][Abstract][Google Scholar], 2013 | 6 | 2013 |
| Novel high-throughput strategy for the aqueous solubility assessment of peptides and proteins exhibiting a propensity for gelation: Application to the discovery of novel … Y Zhang, D Carney, A Henninot, K Srinivasan Molecular Pharmaceutics 18 (1), 469-474, 2020 | 4 | 2020 |
