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Jorge I Alvarez
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Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor
V Rothhammer, ID Mascanfroni, L Bunse, MC Takenaka, JE Kenison, ...
Nature medicine 22 (6), 586-597, 2016
11682016
The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence
JI Alvarez, A Dodelet-Devillers, H Kebir, I Ifergan, PJ Fabre, S Terouz, ...
Science 334 (6063), 1727-1731, 2011
8352011
Microglial control of astrocytes in response to microbial metabolites
V Rothhammer, DM Borucki, EC Tjon, MC Takenaka, CC Chao, ...
Nature 557 (7707), 724-728, 2018
8232018
Preferential recruitment of interferon‐γ–expressing TH17 cells in multiple sclerosis
H Kebir, I Ifergan, JI Alvarez, M Bernard, J Poirier, N Arbour, P Duquette, ...
Annals of Neurology: Official Journal of the American Neurological …, 2009
6542009
Glial influence on the blood brain barrier
JI Alvarez, T Katayama, A Prat
Glia 61 (12), 1939-1958, 2013
5842013
How do immune cells overcome the blood–brain barrier in multiple sclerosis?
C Larochelle, JI Alvarez, A Prat
FEBS letters 585 (23), 3770-3780, 2011
5392011
Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation
L Mayo, SA Trauger, M Blain, M Nadeau, B Patel, JI Alvarez, ...
Nature medicine 20 (10), 1147-1156, 2014
4322014
Disruption of central nervous system barriers in multiple sclerosis
JI Alvarez, R Cayrol, A Prat
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1812 (2), 252-264, 2011
3882011
Immunologic privilege in the central nervous system and the blood–brain barrier
LL Muldoon, JI Alvarez, DJ Begley, RJ Boado, GJ Del Zoppo, ND Doolittle, ...
Journal of Cerebral Blood Flow & Metabolism 33 (1), 13-21, 2013
3412013
leucocyte–endothelial cell crosstalk at the blood–brain barrier: a prerequisite for successful immune cell entry to the brain
J Greenwood, SJ Heasman, JI Alvarez, A Prat, R Lyck, B Engelhardt
Neuropathology and applied neurobiology 37 (1), 24-39, 2011
2852011
Neutrophils mediate blood–spinal cord barrier disruption in demyelinating neuroinflammatory diseases
B Aubé, SA Lévesque, A Paré, É Chamma, H Kébir, R Gorina, ...
The Journal of Immunology 193 (5), 2438-2454, 2014
2342014
Myeloid cell transmigration across the CNS vasculature triggers IL-1β–driven neuroinflammation during autoimmune encephalomyelitis in mice
SA Lévesque, A Paré, B Mailhot, V Bellver-Landete, H Kébir, MA Lécuyer, ...
Journal of Experimental Medicine 213 (6), 929-949, 2016
1702016
Brain granulomas in neurocysticercosis patients are associated with a Th1 and Th2 profile
BI Restrepo, JI Alvarez, JA Castaño, LF Arias, M Restrepo, J Trujillo, ...
Infection and Immunity 69 (7), 4554-4560, 2001
1692001
Role of ninjurin‐1 in the migration of myeloid cells to central nervous system inflammatory lesions
I Ifergan, H Kebir, S Terouz, JI Alvarez, MA Lécuyer, S Gendron, ...
Annals of neurology 70 (5), 751-763, 2011
1672011
Focal disturbances in the blood–brain barrier are associated with formation of neuroinflammatory lesions
JI Alvarez, O Saint-Laurent, A Godschalk, S Terouz, C Briels, S Larouche, ...
Neurobiology of disease 74, 14-24, 2015
1562015
Melanoma cell adhesion molecule identifies encephalitogenic T lymphocytes and promotes their recruitment to the central nervous system
C Larochelle, R Cayrol, H Kebir, JI Alvarez, MA Lecuyer, I Ifergan, E Viel, ...
Brain 135 (10), 2906-2924, 2012
1562012
Netrin 1 regulates blood–brain barrier function and neuroinflammation
C Podjaski, JI Alvarez, L Bourbonniere, S Larouche, S Terouz, JM Bin, ...
Brain 138 (6), 1598-1612, 2015
1552015
Central nervous system recruitment of effector memory CD8+ T lymphocytes during neuroinflammation is dependent on α4 integrin
I Ifergan, H Kebir, JI Alvarez, G Marceau, M Bernard, L Bourbonniere, ...
Brain 134 (12), 3560-3577, 2011
1492011
Central nervous system recruitment of effector memory CD8+ T lymphocytes during neuroinflammation is dependent on α4 integrin
I Ifergan, H Kebir, JI Alvarez, G Marceau, M Bernard, L Bourbonniere, ...
Brain 134 (12), 3560-3577, 2011
1492011
Glial-endothelial crosstalk regulates blood–brain barrier function
L Cheslow, JI Alvarez
Current opinion in pharmacology 26, 39-46, 2016
1192016
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