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Shirin Doroudgar
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ATF6 decreases myocardial ischemia/reperfusion damage and links ER stress and oxidative stress signaling pathways in the heart
JK Jin, EA Blackwood, K Azizi, DJ Thuerauf, AG Fahem, C Hofmann, ...
Circulation research 120 (5), 862-875, 2017
2652017
Mesencephalic astrocyte-derived neurotrophic factor protects the heart from ischemic damage and is selectively secreted upon sarco/endoplasmic reticulum calcium depletion
CC Glembotski, DJ Thuerauf, C Huang, JA Vekich, RA Gottlieb, ...
Journal of Biological Chemistry 287 (31), 25893-25904, 2012
2142012
Ischemia activates the ATF6 branch of the endoplasmic reticulum stress response
S Doroudgar, DJ Thuerauf, MC Marcinko, PJ Belmont, CC Glembotski
Journal of Biological Chemistry 284 (43), 29735-29745, 2009
1952009
The cardiokine story unfolds: ischemic stress-induced protein secretion in the heart
S Doroudgar, CC Glembotski
Trends in molecular medicine 17 (4), 207-214, 2011
1252011
Hrd1 and ER-associated protein degradation, ERAD, are critical elements of the adaptive ER stress response in cardiac myocytes
S Doroudgar, M Völkers, DJ Thuerauf, M Khan, S Mohsin, JL Respress, ...
Circulation research 117 (6), 536-546, 2015
1102015
Muscle 2-Volume Set: Fundamental Biology and Mechanisms of Disease
J Hill, E Olson
Academic Press, 2012
1102012
Mechanistic target of rapamycin complex 2 protects the heart from ischemic damage
M Völkers, MH Konstandin, S Doroudgar, H Toko, P Quijada, S Din, ...
Circulation 128 (19), 2132-2144, 2013
1062013
Pathological hypertrophy amelioration by PRAS40-mediated inhibition of mTORC1
M Völkers, H Toko, S Doroudgar, S Din, P Quijada, AY Joyo, L Ornelas, ...
Proceedings of the National Academy of Sciences 110 (31), 12661-12666, 2013
1012013
New concepts of endoplasmic reticulum function in the heart: programmed to conserve
S Doroudgar, CC Glembotski
Journal of Molecular and Cellular Cardiology 55, 85-91, 2013
992013
ATF6 regulates cardiac hypertrophy by transcriptional induction of the mTORC1 activator, Rheb
EA Blackwood, C Hofmann, M Santo Domingo, AS Bilal, A Sarakki, ...
Circulation research 124 (1), 79-93, 2019
912019
Junctophilin-2 gene therapy rescues heart failure by normalizing RyR2-mediated Ca2+ release
JO Reynolds, AP Quick, Q Wang, DL Beavers, LE Philippen, J Showell, ...
International journal of cardiology 225, 371-380, 2016
862016
PRAS40 prevents development of diabetic cardiomyopathy and improves hepatic insulin sensitivity in obesity
M Völkers, S Doroudgar, N Nguyen, MH Konstandin, P Quijada, S Din, ...
EMBO molecular medicine 6 (1), 57-65, 2014
762014
Regulation of cardiac hypertrophic signaling by prolyl isomerase Pin1
H Toko, MH Konstandin, S Doroudgar, L Ormachea, E Joyo, AY Joyo, ...
Circulation research 112 (9), 1244-1252, 2013
542013
Monitoring cell-type–specific gene expression using ribosome profiling in vivo during cardiac hemodynamic stress
S Doroudgar, C Hofmann, E Boileau, B Malone, E Riechert, AA Gorska, ...
Circulation research 125 (4), 431-448, 2019
482019
Limitation of individual folding resources in the ER leads to outcomes distinct from the unfolded protein response
D Eletto, A Maganty, D Eletto, D Dersh, C Makarewich, C Biswas, ...
Journal of cell science 125 (20), 4865-4875, 2012
432012
CRISPR-mediated activation of endogenous gene expression in the postnatal heart
E Schoger, KJ Carroll, LM Iyer, JR McAnally, W Tan, N Liu, C Noack, ...
Circulation research 126 (1), 6-24, 2020
412020
Protein misfolding in cardiac disease
C Hofmann, HA Katus, S Doroudgar
Circulation 139 (18), 2085-2088, 2019
372019
ER stress-induced secretion of proteins and their extracellular functions in the heart
BA Meyer, S Doroudgar
Cells 9 (9), 2066, 2020
342020
Mesencephalic astrocyte–derived neurotrophic factor is an ER-resident chaperone that protects against reductive stress in the heart
A Arrieta, EA Blackwood, WT Stauffer, M Santo Domingo, AS Bilal, ...
Journal of Biological Chemistry 295 (22), 7566-7583, 2020
342020
Cardiovascular adverse events in multiple myeloma patients
MB Heckmann, S Doroudgar, HA Katus, LH Lehmann
Journal of thoracic disease 10 (Suppl 35), S4296, 2018
292018
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Articles 1–20