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Sara Insausti Gonzalez
Sara Insausti Gonzalez
Postdoctoral Researcher, University of the Basque Country (EHU/UPV)
Verified email at ehu.eus
Title
Cited by
Cited by
Year
Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions
P Carravilla, J Chojnacki, E Rujas, S Insausti, E Largo, D Waithe, ...
Nature communications 10 (1), 78, 2019
392019
Functional optimization of broadly neutralizing HIV-1 antibody 10E8 by promotion of membrane interactions
E Rujas, DP Leaman, S Insausti, L Ortigosa-Pascual, L Zhang, MB Zwick, ...
Journal of virology 92 (8), 10.1128/jvi. 02249-17, 2018
292018
Engineering pan–HIV-1 neutralization potency through multispecific antibody avidity
E Rujas, H Cui, J Burnie, CB Aschner, T Zhao, S Insausti, K Muthuraman, ...
Proceedings of the National Academy of Sciences 119 (4), e2112887119, 2022
142022
Functional contacts between MPER and the anti-HIV-1 broadly neutralizing antibody 4E10 extend into the core of the membrane
E Rujas, S Insausti, M García-Porras, R Sánchez-Eugenia, K Tsumoto, ...
Journal of molecular biology 429 (8), 1213-1226, 2017
142017
Affinity for the interface underpins potency of antibodies operating in membrane environments
E Rujas, S Insausti, DP Leaman, P Carravilla, S González-Resines, ...
Cell reports 32 (7), 2020
102020
Peripheral membrane interactions boost the engagement by an anti-HIV-1 broadly neutralizing antibody
E Rujas, JMM Caaveiro, S Insausti, M García-Porras, K Tsumoto, JL Nieva
Journal of Biological Chemistry 292 (13), 5571-5583, 2017
102017
Cholesterol constrains the antigenic configuration of the membrane-proximal neutralizing HIV-1 epitope
J Torralba, I de la Arada, P Carravilla, S Insausti, E Rujas, E Largo, ...
ACS Infectious Diseases 6 (8), 2155-2168, 2020
92020
Molecular recognition of a membrane-anchored HIV-1 pan-neutralizing epitope
J Torralba, I de la Arada, A Partida-Hanon, E Rujas, M Arribas, S Insausti, ...
Communications biology 5 (1), 1265, 2022
22022
Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile
E Rujas, DP Leaman, S Insausti, P Carravilla, M García-Porras, E Largo, ...
Iscience 24 (9), 2021
12021
A two‐step mechanism for the binding of the HIV‐1 MPER epitope by the 10 E 8 antibody onto biosensor‐supported lipid bilayers
M García‐Porras, J Torralba, S Insausti, J Valle, D Andreu, B Apellániz, ...
FEBS letters, 2024
2024
Espektro zabaleko antigorputzen rola GIBaren aurkako terapian eta prebentzioan
B Apellániz, S Insausti
EKAIA EHUko Zientzia eta Teknologia aldizkaria, 2023
2023
Functional Delineation of a Protein–Membrane Interaction Hotspot Site on the HIV-1 Neutralizing Antibody 10E8
S Insausti, M Garcia-Porras, J Torralba, I Morillo, A Ramos-Caballero, ...
International journal of molecular sciences 23 (18), 10767, 2022
2022
Interactions through the membrane-accommodation surface improve the biological function of broadly neutralizing HIV-1 antibody 10E8
S Insausti, E Rujas, DP Leaman, P Carravilla, J Chojnacki, ...
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 48, S246-S246, 2019
2019
Lipid bilayer stabilization for the correct exposure of MPER epitope in peptide-liposome vaccines targeting the gp41 subunit of HIV-1 Env
J Torralba, I de la Arada, E Largo, E Rujas, S Insausti, P Carravilla, ...
PROTEIN-LIPID NANOSTRUCTURES: FROM DOMAINS TO DEVICES, 43, 2019
2019
Anti-HIV antibody-lipid interactions enhance affinity for the native Env glycoprotein as revealed by single virion STED microscopy
P Carravilla, J Chojnacki, E Rujas, S Insausti, E Largo, D Waithe, ...
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 48, S189-S189, 2019
2019
Single Virion Super-Resolution Microscopy Unveils Mechanistic Details of Env Glycoprotein Recognition by the Broadly Neutralizing HIV-1 Antibodies 4E10 and 10E8
P Carravilla, E Rujas, IR Oar-Arteta, S Insausti, E Largo, J Chojnacki, ...
Biophysical Journal 114 (3), 537a, 2018
2018
Antibacterial and Virucidal Activity of Cu Doped Chromium Nitride Crn-Cu Films Deposited by High Impulse Power Magnetron Sputtering
I Braceras, S Dominguez-Meister, J Mediavilla, A Dianova, N Álvarez, ...
Available at SSRN 4664392, 0
On the Antimicrobial Properties and Endurance of Eugenol and 2-Phenylphenol Functionalized Sol-Gel Coatings
A Suárez-Vega, G Berriozabal, J Perez de Iriarte, J Lorenzo, N Álvarez, ...
Available at SSRN 4510636, 0
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