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Takayoshi Awakawa
Takayoshi Awakawa
Team leader, Riken CSRS
Verified email at mol.f.u-tokyo.ac.jp
Title
Cited by
Cited by
Year
Complete biosynthetic pathway of anditomin: nature’s sophisticated synthetic route to a complex fungal meroterpenoid
Y Matsuda, T Wakimoto, T Mori, T Awakawa, I Abe
Journal of the American Chemical Society 136 (43), 15326-15336, 2014
1622014
Pentaketide resorcylic acid synthesis by type III polyketide synthase from Neurospora crassa
N Funa, T Awakawa, S Horinouchi
Journal of biological chemistry 282 (19), 14476-14481, 2007
1472007
Calyculin biogenesis from a pyrophosphate protoxin produced by a sponge symbiont
T Wakimoto, Y Egami, Y Nakashima, Y Wakimoto, T Mori, T Awakawa, ...
Nature chemical biology 10 (8), 648-655, 2014
1392014
Physically discrete β-lactamase-type thioesterase catalyzes product release in atrochrysone synthesis by iterative type I polyketide synthase
T Awakawa, K Yokota, N Funa, F Doi, N Mori, H Watanabe, S Horinouchi
Chemistry & biology 16 (6), 613-623, 2009
1382009
Characterization of giant modular PKSs provides insight into genetic mechanism for structural diversification of aminopolyol polyketides
L Zhang, T Hashimoto, B Qin, J Hashimoto, I Kozone, T Kawahara, ...
Angewandte Chemie International Edition 56 (7), 1740-1745, 2017
1332017
Spiro-ring formation is catalyzed by a multifunctional dioxygenase in austinol biosynthesis
Y Matsuda, T Awakawa, T Wakimoto, I Abe
Journal of the American Chemical Society 135 (30), 10962-10965, 2013
1252013
Reconstituted biosynthesis of fungal meroterpenoid andrastin A
Y Matsuda, T Awakawa, I Abe
Tetrahedron 69 (38), 8199-8204, 2013
1182013
Comparative transcriptomics as a guide to natural product discovery and biosynthetic gene cluster functionality
GCA Amos, T Awakawa, RN Tuttle, AC Letzel, MC Kim, Y Kudo, W Fenical, ...
Proceedings of the National Academy of Sciences 114 (52), E11121-E11130, 2017
1132017
Uncovering the unusual D-ring construction in terretonin biosynthesis by collaboration of a multifunctional cytochrome P450 and a unique isomerase
Y Matsuda, T Iwabuchi, T Wakimoto, T Awakawa, I Abe
Journal of the American Chemical Society 137 (9), 3393-3401, 2015
1092015
Discovery of Key Dioxygenases that Diverged the Paraherquonin and Acetoxydehydroaustin Pathways in Penicillium brasilianum
Y Matsuda, T Iwabuchi, T Fujimoto, T Awakawa, Y Nakashima, T Mori, ...
Journal of the American Chemical Society 138 (38), 12671-12677, 2016
1052016
Multiplexing of combinatorial chemistry in antimycin biosynthesis: expansion of molecular diversity and utility
Y Yan, J Chen, L Zhang, Q Zheng, Y Han, H Zhang, D Zhang, T Awakawa, ...
Angewandte Chemie 125 (47), 12534-12538, 2013
922013
Terretonin biosynthesis requires methylation as essential step for cyclization
Y Matsuda, T Awakawa, T Itoh, T Wakimoto, T Kushiro, I Fujii, Y Ebizuka, ...
ChemBioChem 13 (12), 1738-1741, 2012
882012
A methyltransferase initiates terpene cyclization in teleocidin B biosynthesis
T Awakawa, L Zhang, T Wakimoto, S Hoshino, T Mori, T Ito, J Ishikawa, ...
Journal of the American Chemical Society 136 (28), 9910-9913, 2014
812014
Direct transfer of starter substrates from type I fatty acid synthase to type III polyketide synthases in phenolic lipid synthesis
A Miyanaga, N Funa, T Awakawa, S Horinouchi
Proceedings of the National Academy of Sciences 105 (3), 871-876, 2008
812008
Biosynthesis of helvolic acid and identification of an unusual C-4-demethylation process distinct from sterol biosynthesis
JM Lv, D Hu, H Gao, T Kushiro, T Awakawa, GD Chen, CX Wang, I Abe, ...
Nature communications 8 (1), 1644, 2017
792017
Induced production of mycotoxins in an endophytic fungus from the medicinal plant Datura stramonium L.
J Sun, T Awakawa, H Noguchi, I Abe
Bioorganic & medicinal chemistry letters 22 (20), 6397-6400, 2012
792012
Complete biosynthetic pathways of ascofuranone and ascochlorin in Acremonium egyptiacum
Y Araki, T Awakawa, M Matsuzaki, R Cho, Y Matsuda, S Hoshino, ...
Proceedings of the National Academy of Sciences 116 (17), 8269-8274, 2019
782019
Structure function and engineering of multifunctional non-heme iron dependent oxygenases in fungal meroterpenoid biosynthesis
Y Nakashima, T Mori, H Nakamura, T Awakawa, S Hoshino, M Senda, ...
Nature communications 9 (1), 104, 2018
672018
Pyranonigrin E: a PKS-NRPS hybrid metabolite from Aspergillus niger identified by genome mining
T Awakawa, XL Yang, T Wakimoto, I Abe
Chembiochem: a European journal of chemical biology 14 (16), 2095-2099, 2013
662013
Arcyriaflavin E, a new cytotoxic indolocarbazole alkaloid isolated by combined-culture of mycolic acid-containing bacteria and Streptomyces cinnamoneus NBRC 13823
S Hoshino, L Zhang, T Awakawa, T Wakimoto, H Onaka, I Abe
The Journal of Antibiotics 68 (5), 342-344, 2015
652015
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Articles 1–20