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Ruben D. Carrasco
Ruben D. Carrasco
Dana-Farber Cancer Institute
Verified email at dfci.harvard.edu
Title
Cited by
Cited by
Year
FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis
JH Paik, R Kollipara, G Chu, H Ji, Y Xiao, Z Ding, L Miao, Z Tothova, ...
Cell 128 (2), 309-323, 2007
11802007
International Myeloma Working Group molecular classification of multiple myeloma: spotlight review
R Fonseca, PL Bergsagel, J Drach, J Shaughnessy, N Gutierrez, ...
Leukemia 23 (12), 2210-2221, 2009
11752009
Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis
NE Sharpless, N Bardeesy, KH Lee, D Carrasco, DH Castrillon, ...
Nature 413 (6851), 86-91, 2001
9952001
Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κB/Rel family
F Weih, D Carrasco, SK Durham, DS Barton, CA Rizzo, RP Ryseck, ...
Cell 80 (2), 331-340, 1995
9861995
Pretreatment mitochondrial priming correlates with clinical response to cytotoxic chemotherapy
TN Chonghaile, KA Sarosiek, TT Vo, JA Ryan, A Tammareddi, ...
Science 334 (6059), 1129-1133, 2011
6282011
A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance
D Chauhan, Z Tian, B Nicholson, KGS Kumar, B Zhou, R Carrasco, ...
Cancer cell 22 (3), 345-358, 2012
5592012
High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients
DR Carrasco, G Tonon, Y Huang, Y Zhang, R Sinha, B Feng, JP Stewart, ...
Cancer cell 9 (4), 313-325, 2006
5222006
The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis
DR Carrasco, K Sukhdeo, M Protopopova, R Sinha, M Enos, DE Carrasco, ...
Cancer cell 11 (4), 349-360, 2007
4822007
Class IIa HDAC inhibition reduces breast tumours and metastases through anti-tumour macrophages
JL Guerriero, A Sotayo, HE Ponichtera, JA Castrillon, AL Pourzia, ...
Nature 543 (7645), 428-432, 2017
4812017
Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation
N Bardeesy, M Sinha, AF Hezel, S Signoretti, NA Hathaway, ...
Nature 419 (6903), 162-167, 2002
4792002
Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing
KK Wong, RS Maser, RM Bachoo, J Menon, DR Carrasco, Y Gu, FW Alt, ...
Nature 421 (6923), 643-648, 2003
4562003
Bortezomib induces canonical nuclear factor-κB activation in multiple myeloma cells
T Hideshima, H Ikeda, D Chauhan, Y Okawa, N Raje, K Podar, ...
Blood, The Journal of the American Society of Hematology 114 (5), 1046-1052, 2009
4412009
Constitutive telomerase expression promotes mammary carcinomas in aging mice
SE Artandi, S Alson, MK Tietze, NE Sharpless, S Ye, RA Greenberg, ...
Proceedings of the National Academy of Sciences 99 (12), 8191-8196, 2002
3922002
Pathogenesis of myeloma
KC Anderson, RD Carrasco
Annual Review of Pathology: Mechanisms of Disease 6, 249-274, 2011
3692011
Relative mitochondrial priming of myeloblasts and normal HSCs determines chemotherapeutic success in AML
TT Vo, J Ryan, R Carrasco, D Neuberg, DJ Rossi, RM Stone, ...
Cell 151 (2), 344-355, 2012
3662012
Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features
AK Azab, J Hu, P Quang, F Azab, C Pitsillides, R Awwad, B Thompson, ...
Blood, The Journal of the American Society of Hematology 119 (24), 5782-5794, 2012
3492012
A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance
Z Tian, P D’Arcy, X Wang, A Ray, YT Tai, Y Hu, RD Carrasco, ...
Blood, The Journal of the American Society of Hematology 123 (5), 706-716, 2014
3272014
MHC class I chain-related protein A antibodies and shedding are associated with the progression of multiple myeloma
M Jinushi, M Vanneman, NC Munshi, YT Tai, RH Prabhala, J Ritz, ...
Proceedings of the National Academy of Sciences 105 (4), 1285-1290, 2008
3182008
Rescue of Hippo coactivator YAP1 triggers DNA damage–induced apoptosis in hematological cancers
F Cottini, T Hideshima, C Xu, M Sattler, M Dori, L Agnelli, E Ten Hacken, ...
Nature medicine 20 (6), 599-606, 2014
3092014
A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma
G Görgün, E Calabrese, T Hideshima, J Ecsedy, G Perrone, M Mani, ...
Blood, The Journal of the American Society of Hematology 115 (25), 5202-5213, 2010
3062010
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