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John Michael Krill-Burger
John Michael Krill-Burger
Senior Scientist, Merck
Verified email at merck.com - Homepage
Title
Cited by
Cited by
Year
Defining a cancer dependency map
A Tsherniak, F Vazquez, PG Montgomery, BA Weir, G Kryukov, ...
Cell 170 (3), 564-576. e16, 2017
20102017
Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration
JM McFarland, ZV Ho, G Kugener, JM Dempster, PG Montgomery, ...
Nature communications 9 (1), 4610, 2018
3282018
Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry
AD Durbin, MW Zimmerman, NV Dharia, BJ Abraham, AB Iniguez, ...
Nature genetics 50 (9), 1240-1246, 2018
2212018
Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets
JM Dempster, C Pacini, S Pantel, FM Behan, T Green, J Krill-Burger, ...
Nature communications 10 (1), 5817, 2019
1802019
CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2
L Chen, G Alexe, NV Dharia, L Ross, AB Iniguez, AS Conway, EJ Wang, ...
The Journal of clinical investigation 128 (1), 446-462, 2018
1362018
EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression
A Renneville, P Van Galen, MC Canver, M McConkey, JM Krill-Burger, ...
Blood, The Journal of the American Society of Hematology 126 (16), 1930-1939, 2015
1102015
Multiplex CRISPR/Cas9-based genome editing in human hematopoietic stem cells models clonal hematopoiesis and myeloid neoplasia
Z Tothova, JM Krill-Burger, KD Popova, CC Landers, QL Sievers, ...
Cell Stem Cell 21 (4), 547-555. e8, 2017
932017
A first-generation pediatric cancer dependency map
NV Dharia, G Kugener, LM Guenther, CF Malone, AD Durbin, AL Hong, ...
Nature genetics 53 (4), 529-538, 2021
882021
Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers
T Ito, MJ Young, R Li, S Jain, A Wernitznig, JM Krill-Burger, CT Lemke, ...
Nature genetics 53 (12), 1664-1672, 2021
782021
MDM2 and MDM4 are therapeutic vulnerabilities in malignant rhabdoid tumors
TP Howard, TE Arnoff, MR Song, AO Giacomelli, X Wang, AL Hong, ...
Cancer research 79 (9), 2404-2414, 2019
532019
Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer
SR Viswanathan, MF Nogueira, CG Buss, JM Krill-Burger, MJ Wawer, ...
Nature genetics 50 (7), 937-943, 2018
532018
STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma
B Adane, G Alexe, BKA Seong, D Lu, EE Hwang, D Hnisz, CA Lareau, ...
Cancer cell 39 (6), 827-844. e10, 2021
512021
Cohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML
Z Tothova, AL Valton, RA Gorelov, M Vallurupalli, JM Krill-Burger, ...
JCI insight 6 (3), 2021
502021
Serum protein profiles predict coronary artery disease in symptomatic patients referred for coronary angiography
WA LaFramboise, R Dhir, LA Kelly, P Petrosko, JM Krill-Burger, CM Sciulli, ...
BMC medicine 10, 1-11, 2012
502012
Expression analysis of human adipose-derived stem cells during in vitro differentiation to an adipocyte lineage
L Satish, JM Krill-Burger, PH Gallo, SD Etages, F Liu, BJ Philips, S Ravuri, ...
BMC Medical Genomics 8, 1-12, 2015
492015
Renal cell neoplasms contain shared tumor type–specific copy number variations
JM Krill-Burger, MA Lyons, LA Kelly, CM Sciulli, P Petrosko, UR Chandran, ...
The American journal of pathology 180 (6), 2427-2439, 2012
342012
Proteins secreted by embryonic stem cells activate cardiomyocytes through ligand binding pathways
WA LaFramboise, P Petrosko, JM Krill-Burger, DR Morris, AR McCoy, ...
Journal of proteomics 73 (5), 992-1003, 2010
332010
Fibroblasts from phenotypically normal palmar fascia exhibit molecular profiles highly similar to fibroblasts from active disease in Dupuytren's Contracture
L Satish, WA LaFramboise, S Johnson, L Vi, A Njarlangattil, C Raykha, ...
BMC medical genomics 5, 1-14, 2012
312012
Synthetic lethal interaction between the ESCRT paralog enzymes VPS4A and VPS4B in cancers harboring loss of chromosome 18q or 16q
JE Neggers, BR Paolella, A Asfaw, MV Rothberg, TA Skipper, A Yang, ...
Cell reports 33 (11), 2020
292020
Small-molecule and CRISPR screening converge to reveal receptor tyrosine kinase dependencies in pediatric rhabdoid tumors
EM Oberlick, MG Rees, B Seashore-Ludlow, F Vazquez, GM Nelson, ...
Cell reports 28 (9), 2331-2344. e8, 2019
282019
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Articles 1–20