| IκB kinases phosphorylate NF-κB p65 subunit on serine 536 in the transactivation domain H Sakurai, H Chiba, H Miyoshi, T Sugita, W Toriumi Journal of Biological Chemistry 274 (43), 30353-30356, 1999 | 1039 | 1999 |
| Distinct roles of the IκB kinase α and β subunits in liberating nuclear factor κB (NF-κB) from IκB and in phosphorylating the p65 subunit of NF-κB N Sizemore, N Lerner, N Dombrowski, H Sakurai, GR Stark Journal of Biological Chemistry 277 (6), 3863-3869, 2002 | 477 | 2002 |
| Tumor necrosis factor-α-induced IKK phosphorylation of NF-κB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway H Sakurai, S Suzuki, N Kawasaki, H Nakano, T Okazaki, A Chino, T Doi, ... Journal of Biological Chemistry 278 (38), 36916-36923, 2003 | 467 | 2003 |
| Targeting of TAK1 in inflammatory disorders and cancer H Sakurai Trends in pharmacological sciences 33 (10), 522-530, 2012 | 381 | 2012 |
| Receptor activator of NF-κB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6 J Mizukami, G Takaesu, H Akatsuka, H Sakurai, J Ninomiya-Tsuji, ... Molecular and cellular biology 22 (4), 992-1000, 2002 | 348 | 2002 |
| Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling M Yamamoto, T Okamoto, K Takeda, S Sato, H Sanjo, S Uematsu, ... Nature immunology 7 (9), 962-970, 2006 | 327 | 2006 |
| Role of the CXCL12/CXCR4 axis in peritoneal carcinomatosis of gastric cancer K Yasumoto, K Koizumi, A Kawashima, Y Saitoh, Y Arita, K Shinohara, ... Cancer research 66 (4), 2181-2187, 2006 | 327 | 2006 |
| Functional interactions of transforming growth factor β-activated kinase 1 with IκB kinases to stimulate NF-κB activation H Sakurai, H Miyoshi, W Toriumi, T Sugita Journal of Biological Chemistry 274 (15), 10641-10648, 1999 | 279 | 1999 |
| Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-β-activated kinase 1 (TAK1) in a … P Singhirunnusorn, S Suzuki, N Kawasaki, I Saiki, H Sakurai Journal of Biological Chemistry 280 (8), 7359-7368, 2005 | 231 | 2005 |
| PKCβ regulates BCR-mediated IKK activation by facilitating the interaction between TAK1 and CARMA1 H Shinohara, T Yasuda, Y Aiba, H Sanjo, M Hamadate, H Watarai, ... The Journal of experimental medicine 202 (10), 1423-1431, 2005 | 230 | 2005 |
| High-level expression of chemokine CXCL16 by tumor cells correlates with a good prognosis and increased tumor-infiltrating lymphocytes in colorectal cancer S Hojo, K Koizumi, K Tsuneyama, Y Arita, Z Cui, K Shinohara, T Minami, ... Cancer research 67 (10), 4725-4731, 2007 | 229 | 2007 |
| Identification of NAP1, a regulatory subunit of IκB kinase-related kinases that potentiates NF-κB signaling F Fujita, Y Taniguchi, T Kato, Y Narita, A Furuya, T Ogawa, H Sakurai, ... Molecular and cellular biology 23 (21), 7780-7793, 2003 | 223 | 2003 |
| Phosphorylation-dependent activation of TAK1 mitogen-activated protein kinase kinase kinase by TAB1 H Sakurai, H Miyoshi, J Mizukami, T Sugita FEBS letters 474 (2-3), 141-145, 2000 | 214 | 2000 |
| Vanillin suppresses in vitro invasion and in vivo metastasis of mouse breast cancer cells K Lirdprapamongkol, H Sakurai, N Kawasaki, MK Choo, Y Saitoh, ... European journal of pharmaceutical sciences 25 (1), 57-65, 2005 | 207 | 2005 |
| Phosphorylation of serine 276 is essential for p65 NF-κB subunit-dependent cellular responses T Okazaki, S Sakon, T Sasazuki, H Sakurai, T Doi, H Yagita, K Okumura, ... Biochemical and biophysical research communications 300 (4), 807-812, 2003 | 206 | 2003 |
| Activation of transcription factor NF-κB in experimental glomerulonephritis in rats H Sakurai, Y Hisada, M Ueno, M Sugiura, K Kawashima, T Sugita Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1316 (2), 132-138, 1996 | 181 | 1996 |
| Antitumor anthraquinones from an endophytic actinomycete Micromonospora lupini sp. nov. Y Igarashi, ME Trujillo, E Martínez-Molina, S Yanase, S Miyanaga, ... Bioorganic & Medicinal Chemistry Letters 17 (13), 3702-3705, 2007 | 178 | 2007 |
| Angiotensin II plays a pathogenic role in immune-mediated renal injury in mice Y Hisada, T Sugaya, M Yamanouchi, H Uchida, H Fujimura, H Sakurai, ... The Journal of clinical investigation 103 (5), 627-635, 1999 | 174 | 1999 |
| TAK1 is recruited to the tumor necrosis factor-α (TNF-α) receptor 1 complex in a receptor-interacting protein (RIP)-dependent manner and cooperates with MEKK3 leading to NF-κB … M Blonska, PB Shambharkar, M Kobayashi, D Zhang, H Sakurai, B Su, ... Journal of Biological Chemistry 280 (52), 43056-43063, 2005 | 173 | 2005 |
| Blocking on the CXCR4/mTOR signalling pathway induces the anti-metastatic properties and autophagic cell death in peritoneal disseminated gastric cancer cells I Hashimoto, K Koizumi, M Tatematsu, T Minami, S Cho, N Takeno, ... European journal of cancer 44 (7), 1022-1029, 2008 | 169 | 2008 |
Yoshihiro HayakawaInstitute for Natural Medicine, University of ToyamaVerified email at inm.u-toyama.ac.jp
