Structural roles for human translation factor eIF3 in initiation of protein synthesis B Siridechadilok, CS Fraser, RJ Hall, JA Doudna, E Nogales Science 310 (5753), 1513-1515, 2005 | 327 | 2005 |
Structural and mechanistic insights into hepatitis C viral translation initiation CS Fraser, JA Doudna Nature Reviews Microbiology 5 (1), 29-38, 2007 | 312 | 2007 |
The genome‐linked protein VPg of the Norwalk virus binds eIF3, suggesting its role in translation initiation complex recruitment KF Daughenbaugh, CS Fraser, JWB Hershey, ME Hardy The EMBO journal, 2003 | 305 | 2003 |
Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3 M Zhou, AM Sandercock, CS Fraser, G Ridlova, E Stephens, ... Proceedings of the National Academy of Sciences 105 (47), 18139-18144, 2008 | 296 | 2008 |
Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response C Sidrauski, JC Tsai, M Kampmann, BR Hearn, P Vedantham, ... elife 4, e07314, 2015 | 256 | 2015 |
Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA H Ji, CS Fraser, Y Yu, J Leary, JA Doudna Proceedings of the National Academy of Sciences 101 (49), 16990-16995, 2004 | 253 | 2004 |
Human eIF4E promotes mRNA restructuring by stimulating eIF4A helicase activity K Feoktistova, E Tuvshintogs, A Do, CS Fraser Proceedings of the National Academy of Sciences 110 (33), 13339-13344, 2013 | 203 | 2013 |
Human eukaryotic initiation factor 4G (eIF4G) protein binds to eIF3c,-d, and-e to promote mRNA recruitment to the ribosome N Villa, A Do, JWB Hershey, CS Fraser Journal of Biological Chemistry 288 (46), 32932-32940, 2013 | 186 | 2013 |
Structure of a human 48S translational initiation complex J Brito Querido, M Sokabe, S Kraatz, Y Gordiyenko, JM Skehel, CS Fraser, ... Science 369 (6508), 1220-1227, 2020 | 156 | 2020 |
Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry E Damoc, CS Fraser, M Zhou, H Videler, GL Mayeur, JWB Hershey, ... Molecular & Cellular Proteomics 6 (7), 1135-1146, 2007 | 155 | 2007 |
The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro CS Fraser, JY Lee, GL Mayeur, M Bushell, JA Doudna, JWB Hershey Journal of Biological Chemistry 279 (10), 8946-8956, 2004 | 155 | 2004 |
eIF3j is located in the decoding center of the human 40S ribosomal subunit CS Fraser, KE Berry, JWB Hershey, JA Doudna Molecular cell 26 (6), 811-819, 2007 | 147 | 2007 |
Duplex unwinding and ATPase activities of the DEAD-box helicase eIF4A are coupled by eIF4G and eIF4B AR Özeş, K Feoktistova, BC Avanzino, CS Fraser Journal of molecular biology 412 (4), 674-687, 2011 | 133 | 2011 |
Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3) C Sun, A Todorovic, J Querol-Audí, Y Bai, N Villa, M Snyder, J Ashchyan, ... Proceedings of the National Academy of Sciences 108 (51), 20473-20478, 2011 | 122 | 2011 |
The human translation initiation multi-factor complex promotes methionyl-tRNA i binding to the 40S ribosomal subunit M Sokabe, CS Fraser, JWB Hershey Nucleic acids research 40 (2), 905-913, 2012 | 114 | 2012 |
The mechanism of an exceptional case of reinitiation after translation of a long ORF reveals why such events do not generally occur in mammalian mRNA translation TAA Pöyry, A Kaminski, EJ Connell, CS Fraser, RJ Jackson Genes & development 21 (23), 3149-3162, 2007 | 109 | 2007 |
Factor-dependent processivity in human eIF4A DEAD-box helicase C García-García, KL Frieda, K Feoktistova, CS Fraser, SM Block Science 348 (6242), 1486-1488, 2015 | 99 | 2015 |
Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor eIF3 GL Mayeur, CS Fraser, F Peiretti, KL Block, JWB Hershey European journal of biochemistry 270 (20), 4133-4139, 2003 | 86 | 2003 |
A helicase-independent activity of eIF4A in promoting mRNA recruitment to the human ribosome M Sokabe, CS Fraser Proceedings of the National Academy of Sciences 114 (24), 6304-6309, 2017 | 83 | 2017 |
Human eukaryotic initiation factor 2 (eIF2)-GTP-Met-tRNAi ternary complex and eIF3 stabilize the 43 S preinitiation complex M Sokabe, CS Fraser Journal of Biological Chemistry 289 (46), 31827-31836, 2014 | 73 | 2014 |