| Detection of DNA base modifications by deep recurrent neural network on Oxford Nanopore sequencing data Q Liu, L Fang, G Yu, D Wang, CL Xiao, K Wang Nature communications 10 (1), 2449, 2019 | 270 | 2019 |
| Tumor-derived microRNA-494 promotes angiogenesis in non-small cell lung cancer G Mao, Y Liu, XI Fang, Y Liu, L Fang, L Lin, X Liu, N Wang Angiogenesis 18, 373-382, 2015 | 175 | 2015 |
| PPARgene: a database of experimentally verified and computationally predicted PPAR target genes L Fang, M Zhang, Y Li, Y Liu, Q Cui, N Wang PPAR research 2016, 2016 | 117 | 2016 |
| PrecisionFDA Truth Challenge V2: Calling variants from short and long reads in difficult-to-map regions ND Olson, J Wagner, J McDaniel, SH Stephens, ST Westreich, ... Cell genomics 2 (5), 2022 | 115 | 2022 |
| Adipocyte-specific loss of PPARγ attenuates cardiac hypertrophy X Fang, MJ Stroud, K Ouyang, L Fang, J Zhang, ND Dalton, Y Gu, T Wu, ... JCI insight 1 (16), 2016 | 86 | 2016 |
| Long-read sequencing identified intronic repeat expansions in SAMD12 from Chinese pedigrees affected with familial cortical myoclonic tremor with epilepsy S Zeng, M Zhang, X Wang, Z Hu, J Li, N Li, J Wang, F Liang, Q Yang, ... Journal of medical genetics 56 (4), 265-270, 2019 | 83 | 2019 |
| A map of cis-regulatory elements and 3D genome structures in zebrafish H Yang, Y Luan, T Liu, HJ Lee, L Fang, Y Wang, X Wang, B Zhang, Q Jin, ... Nature 588 (7837), 337-343, 2020 | 81 | 2020 |
| LIQA: long-read isoform quantification and analysis Y Hu, L Fang, X Chen, JF Zhong, M Li, K Wang Genome biology 22 (1), 182, 2021 | 58 | 2021 |
| Phen2Gene: rapid phenotype-driven gene prioritization for rare diseases M Zhao, JM Havrilla, L Fang, Y Chen, J Peng, C Liu, C Wu, M Sarmady, ... NAR genomics and Bioinformatics 2 (2), lqaa032, 2020 | 56 | 2020 |
| Single-molecule optical mapping enables quantitative measurement of D4Z4 repeats in facioscapulohumeral muscular dystrophy (FSHD) Y Dai, P Li, Z Wang, F Liang, F Yang, L Fang, Y Huang, S Huang, J Zhou, ... Journal of Medical Genetics 57 (2), 109-120, 2020 | 54 | 2020 |
| Xenobiotic pregnane X receptor (PXR) regulates innate immunity via activation of NLRP3 inflammasome in vascular endothelial cells S Wang, T Lei, K Zhang, W Zhao, L Fang, B Lai, J Han, L Xiao, N Wang Journal of Biological Chemistry 289 (43), 30075-30081, 2014 | 50 | 2014 |
| NanoCaller for accurate detection of SNPs and indels in difficult-to-map regions from long-read sequencing by haplotype-aware deep neural networks MU Ahsan, Q Liu, L Fang, K Wang Genome biology 22, 1-33, 2021 | 48 | 2021 |
| Single-cell multiomics reveals increased plasticity, resistant populations, and stem-cell–like blasts in KMT2A-rearranged leukemia C Chen, W Yu, F Alikarami, Q Qiu, C Chen, J Flournoy, P Gao, Y Uzun, ... Blood, The Journal of the American Society of Hematology 139 (14), 2198-2211, 2022 | 44 | 2022 |
| GHSR deficiency exacerbates cardiac fibrosis: role in macrophage inflammasome activation and myofibroblast differentiation M Wang, L Qian, J Li, H Ming, L Fang, Y Li, M Zhang, Y Xu, Y Ban, ... Cardiovascular research 116 (13), 2091-2102, 2020 | 37 | 2020 |
| NextSV: a meta-caller for structural variants from low-coverage long-read sequencing data L Fang, J Hu, D Wang, K Wang BMC bioinformatics 19, 1-11, 2018 | 37 | 2018 |
| Pro-inflammatory Macrophages suppress PPARγ activity in Adipocytes via S-nitrosylation R Yin, L Fang, Y Li, P Xue, Y Li, Y Guan, Y Chang, C Chen, N Wang Free Radical Biology and Medicine 89, 895-905, 2015 | 36 | 2015 |
| LinkedSV for detection of mosaic structural variants from linked-read exome and genome sequencing data L Fang, C Kao, MV Gonzalez, FA Mafra, R Pellegrino da Silva, M Li, ... Nature communications 10 (1), 5585, 2019 | 35 | 2019 |
| Transcriptome sequencing unravels potential biomarkers at different stages of cerebral ischemic stroke Y Cai, Y Zhang, X Ke, Y Guo, C Yao, N Tang, P Pang, G Xie, L Fang, ... Frontiers in genetics 10, 814, 2019 | 28 | 2019 |
| Metabonomic profiling revealed an alteration in purine nucleotide metabolism associated with cardiac hypertrophy in rats treated with thiazolidinediones Y Liu, X Yan, G Mao, L Fang, B Zhao, Y Liu, H Tang, N Wang Journal of proteome research 12 (12), 5634-5641, 2013 | 27 | 2013 |
| LongGF: computational algorithm and software tool for fast and accurate detection of gene fusions by long-read transcriptome sequencing Q Liu, Y Hu, A Stucky, L Fang, JF Zhong, K Wang BMC genomics 21, 1-12, 2020 | 26 | 2020 |
Kai WangChildren's Hospital of PhiladelphiaVerified email at email.chop.edu
