Follow
Norman E. Sharpless
Norman E. Sharpless
Former Director, The National Cancer Institute
Verified email at med.unc.edu
Title
Cited by
Cited by
Year
Circular RNAs are abundant, conserved, and associated with ALU repeats
WR Jeck, JA Sorrentino, K Wang, MK Slevin, CE Burd, J Liu, WF Marzluff, ...
Rna 19 (2), 141-157, 2013
41862013
Genomic classification of cutaneous melanoma
R Akbani, KC Akdemir, B áArman Aksoy, M Albert, A Ally, SB Amin, ...
Cell 161 (7), 1681-1696, 2015
27252015
Detecting and characterizing circular RNAs
WR Jeck, NE Sharpless
Nature biotechnology 32 (5), 453-461, 2014
24722014
Ink4a/Arf expression is a biomarker of aging
J Krishnamurthy, C Torrice, MR Ramsey, GI Kovalev, K Al-Regaiey, L Su, ...
The Journal of clinical investigation 114 (9), 1299-1307, 2004
17292004
Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice
J Chang, Y Wang, L Shao, RM Laberge, M Demaria, J Campisi, ...
Nature medicine 22 (1), 78-83, 2016
16732016
Senescence in health and disease
S He, NE Sharpless
Cell 169 (6), 1000-1011, 2017
14772017
Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a
V Janzen, R Forkert, HE Fleming, Y Saito, MT Waring, DM Dombkowski, ...
Nature 443 (7110), 421-426, 2006
12882006
The regulation of INK4/ARF in cancer and aging
WY Kim, NE Sharpless
Cell 127 (2), 265-275, 2006
12282006
LKB1 modulates lung cancer differentiation and metastasis
H Ji, MR Ramsey, DN Hayes, C Fan, K McNamara, P Kozlowski, C Torrice, ...
Nature 448 (7155), 807-810, 2007
11752007
Cellular senescence promotes adverse effects of chemotherapy and cancer relapse. Cancer Discov.
M Demaria, MN O’leary, J Chang, L Shao, S Liu, F Alimirah, K Koenig, ...
CD-16-0241.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 2017
1165*2017
Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing
AV Molofsky, SG Slutsky, NM Joseph, S He, R Pardal, J Krishnamurthy, ...
Nature 443 (7110), 448-452, 2006
11442006
p16INK4a induces an age-dependent decline in islet regenerative potential
J Krishnamurthy, MR Ramsey, KL Ligon, C Torrice, A Koh, S Bonner-Weir, ...
Nature 443 (7110), 453-457, 2006
11072006
How stem cells age and why this makes us grow old
NE Sharpless, RA DePinho
Nature reviews Molecular cell biology 8 (9), 703-713, 2007
10872007
Forging a signature of in vivo senescence
NE Sharpless, CJ Sherr
Nature Reviews Cancer 15 (7), 397-408, 2015
10402015
Expression of Linear and Novel Circular Forms of an INK4/ARF-Associated Non-Coding RNA Correlates with Atherosclerosis Risk
CE Burd, WR Jeck, Y Liu, HK Sanoff, Z Wang, NE Sharpless
PLoS genetics 6 (12), e1001233, 2010
9992010
Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis
NE Sharpless, N Bardeesy, KH Lee, D Carrasco, DH Castrillon, ...
Nature 413 (6851), 86-91, 2001
9962001
Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis
RM Bachoo, EA Maher, KL Ligon, NE Sharpless, SS Chan, MJ You, ...
Cancer cell 1 (3), 269-277, 2002
8382002
Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer
JS Duncan, MC Whittle, K Nakamura, AN Abell, AA Midland, ...
Cell 149 (2), 307-321, 2012
8342012
The mighty mouse: genetically engineered mouse models in cancer drug development
NE Sharpless, RA DePinho
Nature reviews Drug discovery 5 (9), 741-754, 2006
7682006
The INK4A/ARF locus and its two gene products
NE Sharpless, RA DePinho
Current opinion in genetics & development 9 (1), 22-30, 1999
6961999
The system can't perform the operation now. Try again later.
Articles 1–20