| Effect of the protonation state of the titratable residues on the inhibitor affinity to BACE-1 JL Domínguez, T Christopeit, MC Villaverde, T Gossas, JM Otero, ... Biochemistry 49 (34), 7255-7263, 2010 | 55 | 2010 |
| Computer-Aided Structure-Based Design of Multitarget Leads for Alzheimer’s Disease JL Domínguez, F Fernández-Nieto, M Castro, M Catto, MR Paleo, S Porto, ... Journal of chemical information and modeling 55 (1), 135-148, 2014 | 51 | 2014 |
| Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth M Palomo-Guerrero, R Fadó, M Casas, M Pérez-Montero, M Baena, ... Elife 8, e51063, 2019 | 31 | 2019 |
| Sensing of nutrients by CPT1C controls SAC1 activity to regulate AMPA receptor trafficking M Casas, R Fadó, JL Domínguez, A Roig, M Kaku, S Chohnan, M Solé, ... Journal of Cell Biology 219 (10), 2020 | 30 | 2020 |
| On the active site protonation state in aspartic proteases: implications for drug design F Sussman, MC Villaverde, J L Dominguez, UH Danielson Current pharmaceutical design 19 (23), 4257-4275, 2013 | 29 | 2013 |
| On a possible neutral charge state for the catalytic dyad in β-secretase when bound to hydroxyethylene transition state analogue inhibitors F Sussman, JM Otero, MC Villaverde, M Castro, JL Domínguez, ... Journal of medicinal chemistry 54 (8), 3081-3085, 2011 | 14 | 2011 |
| How peptide/MHC presence affects the dynamics of the LC13 T-cell receptor JL Dominguez, B Knapp Scientific reports 9 (1), 1-11, 2019 | 10 | 2019 |
| Experimental and ‘in silico’analysis of the effect of pH on HIV-1 protease inhibitor affinity: Implications for the charge state of the protein ionogenic groups JL Domínguez, T Gossas, MC Villaverde, UH Danielson, F Sussman Bioorganic & medicinal chemistry 20 (15), 4838-4847, 2012 | 9 | 2012 |
| 8‐Aminomethyl‐7‐hydroxy‐4‐methylcoumarins as Multitarget Leads for Alzheimer's Disease JL Domínguez, F Fernández‐Nieto, JM Brea, M Catto, MR Paleo, S Porto, ... ChemistrySelect 1 (11), 2742-2749, 2016 | 8 | 2016 |
| Effect of pH and ligand charge state on BACE-1 fragment docking performance JL Domínguez, MC Villaverde, F Sussman Journal of computer-aided molecular design 27 (5), 403-417, 2013 | 8 | 2013 |
