Linking increased airway hydration, ciliary beating, and mucociliary clearance through ENaC inhibition ABM Aastrand, M Hemmerling, J Root, C Wingren, J Pesic, E Johansson, ... American Journal of Physiology 308, L22-L32, 2015 | 78 | 2015 |
Selective nonsteroidal glucocorticoid receptor modulators for the inhaled treatment of pulmonary diseases M Hemmerling, S Nilsson, K Edman, S Eirefelt, W Russell, R Hendrickx, ... Journal of Medicinal Chemistry 60 (20), 8591-8605, 2017 | 54 | 2017 |
Chemical Compounds 572 M Berger, J Dahmén, K Edman, A Eriksson, B Gabos, T Hansson, ... US Patent App. 13/429,177, 2012 | 51 | 2012 |
Investigation of the Lewis acid mediated stereoselective cyclization of cationic aminyl radicals leading to substituted pyrrolidines Å Sjöholm, M Hemmerling, N Pradeille, P Somfai Journal of the Chemical Society, Perkin Transactions 1, 891-899, 2001 | 29 | 2001 |
Probing the diastereoselectivity in the cyclization of cationic aminyl radicals M Hemmerling, Å Sjöholm, P Somfai Tetrahedron: Asymmetry 10 (21), 4091-4094, 1999 | 25 | 1999 |
Precise and systematic end group chemistry modifications on PAMAM and poly (l-lysine) dendrimers to improve cytosolic delivery of mRNA F Joubert, MJ Munson, A Sabirsh, RM England, M Hemmerling, ... Journal of Controlled Release 356, 580-594, 2023 | 22 | 2023 |
Acetogenic isoquinoline alkaloids. XXIII. Structure of the naphthyl isoquinoline alkaloid dioncophylline A G Bringmann, R Zagst, B Schöner, H Busse, M Hemmerling, C Burschka Acta Crystallographica Section C: Crystal Structure Communications 47 (8 …, 1991 | 21 | 1991 |
Discovery of indazole ethers as novel, potent, non-steroidal glucocorticoid receptor modulators M Hemmerling, K Edman, M Lepistö, A Eriksson, S Ivanova, J Dahmén, ... Bioorganic & Medicinal Chemistry Letters 26 (23), 5741-5748, 2016 | 20 | 2016 |
Potential strategies for increasing drug-discovery productivity JG Cumming, MRV Finlay, F Giordanetto, M Hemmerling, T Lister, ... Future Medicinal Chemistry 6, 515-527, 2014 | 18 | 2014 |
Hydroxyalkyl compounds T Eriksson, P Hansen, M Hemmerling, K Henriksson, T Klingstedt, ... US Patent 6,943,188, 2005 | 16 | 2005 |
Phenyl and benzodioxinyl substituted indazoles derivatives M Berger, H Rehwinkel, J Dahmén, A Eriksson, T Hansson, N Hossain, ... US Patent 8,211,930, 2012 | 13 | 2012 |
Phenyl or Pyridinyl Substituted Indazoles Derivatives M Berger, H Rehwinkel, J Dahmén, T Hansson, N Hossain, H Johanssson, ... US Patent App. 12/468,494, 2010 | 12 | 2010 |
Chemical compounds 572 M Berger, J Dahmén, K Edman, A Eriksson, B Gabos, T Hansson, ... US Patent 7,728,030, 2010 | 11 | 2010 |
Chemical compounds M Berger, L Bergstrom, J Dahmen, A Eriksson, B Gabos, M Hemmerling, ... US Patent App. 11/986,555, 2008 | 11 | 2008 |
Indazolyl sulphonamide derivatives useful as glucocorticoid modulators M Berger, L Bergstrom, J Dahmen, A Eriksson, B Gabos, M Hemmerling, ... US Patent 8,030,340, 2011 | 7 | 2011 |
Chemical Compounds 572 M Berger, J Dahmén, K Edman, A Eriksson, B Gabos, T Hansson, ... US Patent App. 12/643,504, 2010 | 7 | 2010 |
Imidazo and thiazolopyridines as JAK3 kinase inhibitors M Hemmerling, T Klingstedt US Patent App. 10/556,228, 2006 | 7 | 2006 |
New generation ENaC inhibitors detach cystic fibrosis airway mucus bundles via sodium/hydrogen exchanger inhibition M Giorgetti, N Klymiuk, A Bähr, M Hemmerling, L Jinton, R Tarran, ... European journal of pharmacology 904, 174123, 2021 | 6 | 2021 |
Discovery of AZD5423, a potent and selective non-steroidal glucocorticoid receptor modulator for the inhaled treatment of respiratory diseases T Hansson, M Berger, J Dahmen, K Edman, A Eriksson, B Gabos, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 245, 2013 | 5 | 2013 |
Chemical compounds 572 M Berger, J Dahmén, K Edman, A Eriksson, B Gabos, T Hansson, ... US Patent 8,143,290, 2012 | 5 | 2012 |