Efficacy of Sym004 in patients with metastatic colorectal cancer with acquired resistance to anti-EGFR therapy and molecularly selected by circulating tumor DNA analyses: a … C Montagut, G Argilés, F Ciardiello, TT Poulsen, R Dienstmann, M Kragh, ... JAMA oncology 4 (4), e175245-e175245, 2018 | 108 | 2018 |
The first-in-class anti-EGFR antibody mixture Sym004 overcomes cetuximab resistance mediated by EGFR extracellular domain mutations in colorectal cancer FJ Sánchez-Martín, B Bellosillo, M Gelabert-Baldrich, A Dalmases, ... Clinical Cancer Research 22 (13), 3260-3267, 2016 | 69 | 2016 |
Aryl hydrocarbon receptor‐dependent induction of apoptosis by 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin in cerebellar granule cells from mouse FJ Sánchez‐Martín, PM Fernández‐Salguero, JM Merino Journal of neurochemistry 118 (1), 153-162, 2011 | 61 | 2011 |
NMDA-induced neuroprotection in hippocampal neurons is mediated through the protein kinase A and CREB (cAMP-response element-binding protein) pathway E Valera, FJ Sánchez-Martín, AV Ferrer-Montiel, Á Messeguer, JM Merino Neurochemistry international 53 (5), 148-154, 2008 | 59 | 2008 |
Sex-and tissue-specific methylome changes in brains of mice perinatally exposed to lead FJ Sánchez-Martín, DM Lindquist, J Landero-Figueroa, X Zhang, J Chen, ... Neurotoxicology 46, 92-100, 2015 | 48 | 2015 |
2,3,7,8-Tetrachlorodibenzo-p-dioxin induces apoptosis by disruption of intracellular calcium homeostasis in human neuronal cell line SHSY5Y A Morales-Hernández, FJ Sánchez-Martín, MP Hortigón-Vinagre, ... Apoptosis 17, 1170-1181, 2012 | 47 | 2012 |
2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin induces apoptosis in neural growth factor (NGF)-differentiated pheochromocytoma PC12 cells FJ Sánchez-Martín, PM Fernández-Salguero, JM Merino Neurotoxicology 31 (3), 267-276, 2010 | 41 | 2010 |
HER-family ligands promote acquired resistance to trastuzumab in gastric cancer A Sampera, FJ Sánchez-Martín, O Arpí, L Visa, M Iglesias, S Menéndez, ... Molecular Cancer Therapeutics 18 (11), 2135-2145, 2019 | 36 | 2019 |
Lead induces similar gene expression changes in brains of gestationally exposed adult mice and in neurons differentiated from mouse embryonic stem cells FJ Sánchez-Martín, Y Fan, DM Lindquist, Y Xia, A Puga PLoS One 8 (11), e80558, 2013 | 35 | 2013 |
Nerve growth factor increases the sensitivity to zinc toxicity and induces cell cycle arrest in PC12 cells FJ Sánchez-Martín, E Valera, I Casimiro, JM Merino Brain research bulletin 81 (4-5), 458-466, 2010 | 26 | 2010 |
The role of PIGF blockade in the treatment of colorectal cancer: overcoming the pitfalls T Macarulla, C Montagut, FJ Sánchez-Martin, M Granja, H Verdaguer, ... Expert Opinion on Biological Therapy 20 (1), 15-22, 2020 | 20 | 2020 |
Chromium disrupts chromatin organization and CTCF access to its cognate sites in promoters of differentially expressed genes A VonHandorf, FJ Sánchez-Martín, J Biesiada, H Zhang, X Zhang, ... Epigenetics 13 (4), 363-375, 2018 | 19 | 2018 |
Long-term Coexposure to Hexavalent Chromium and B[a]P Causes Tissue-Specific Differential Biological Effects in Liver and Gastrointestinal Tract of Mice FJ Sánchez-Martín, Y Fan, V Carreira, JL Ovesen, A Vonhandorf, Y Xia, ... Toxicological Sciences 146 (1), 52-64, 2015 | 18 | 2015 |
AhR-dependent 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin toxicity in human neuronal cell line SHSY5Y A Morales-Hernández, M Corrales-Redondo, JM Marcos-Merino, ... NeuroToxicology 56, 55-63, 2016 | 14 | 2016 |
mTOR inhibition and T-DM1 in HER2-positive breast cancer D Casadevall, A Hernández-Prat, S García-Alonso, O Arpí-Llucià, ... Molecular Cancer Research 20 (7), 1108-1121, 2022 | 7 | 2022 |
SRC-S6 axis as a potential mechanism of resistance to anti HER2 treatment in gastric cancer (GC) cell lines V Gambardella, A Sampera, J Castillo, F Sanchez-Martin, ... Annals of Oncology 28, vii16, 2017 | 3 | 2017 |
Prenatal and early postnatal lead exposure in mice: neuroimaging findings DM Lindquist, T Beckwith, KM Cecil, FJ Sánchez-Martín, ... Quantitative imaging in medicine and surgery 5 (4), 511, 2015 | 3 | 2015 |
Efficacy of Sym004 in Patients With Metastatic Colorectal Cancer With Acquired Resistance to Anti-EGFRTherapy and Molecularly Selected by Circulating Tumor DNA Analyses: A … C Montagut, G Argiles, F Ciardiello, TT Poulsen, R Dienstmann, M Kragh, ... JAMA ONCOLOGY 5 (5), 745-745, 2019 | 2 | 2019 |
Identification of molecular mechanisms of acquired resistance to trastuzumab in gastric cancer A Sampera, M Gelabert-Baldrich, FJ Sánchez-Martín, A Dalmases, O Arpi, ... European Journal of Cancer 1 (61), S124-S125, 2016 | 2 | 2016 |
Plasma ctDNA mutation anaysis for identification of initial and acquired resistance to HER2-targeted therapy in advanced gastric cancer patients E Gaye, BB Paricio, L Visa, MI Coma, FJS Martin, AS Borràs, CM Viladot Annals of Oncology 29, vi2, 2018 | 1 | 2018 |