Trained immunity-promoting nanobiologic therapy suppresses tumor growth and potentiates checkpoint inhibition B Priem, MMT van Leent, AJP Teunissen, AM Sofias, VP Mourits, ... Cell 183 (3), 786-801. e19, 2020 | 103 | 2020 |
Immune checkpoint inhibitor therapy aggravates T cell–driven plaque inflammation in atherosclerosis K Poels, MMT van Leent, C Boutros, H Tissot, S Roy, AE Meerwaldt, ... Cardio Oncology 2 (4), 599-610, 2020 | 86 | 2020 |
Tumor Targeting by αvβ3-Integrin-Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking AM Sofias, YC Toner, AE Meerwaldt, MMT van Leent, G Soultanidis, ... ACS nano 14 (7), 7832-7846, 2020 | 76 | 2020 |
Imaging-assisted nanoimmunotherapy for atherosclerosis in multiple species T Binderup, R Duivenvoorden, F Fay, MMT van Leent, J Malkus, S Baxter, ... Science translational medicine 11 (506), eaaw7736, 2019 | 60 | 2019 |
Prosaposin mediates inflammation in atherosclerosis MMT van Leent, TJ Beldman, YC Toner, MA Lameijer, N Rother, ... Science translational medicine 13 (584), eabe1433, 2021 | 49 | 2021 |
Probing myeloid cell dynamics in ischaemic heart disease by nanotracer hot-spot imaging ML Senders, AE Meerwaldt, MMT van Leent, BL Sanchez-Gaytan, ... Nature nanotechnology 15 (5), 398-405, 2020 | 49 | 2020 |
Engineering cytokine therapeutics J Deckers, T Anbergen, AM Hokke, A de Dreu, DP Schrijver, K de Bruin, ... Nature Reviews Bioengineering 1 (4), 286-303, 2023 | 41 | 2023 |
Imaging Cardiovascular and Lung Macrophages With the Positron Emission Tomography Sensor 64Cu-Macrin in Mice, Rabbits, and Pigs M Nahrendorf, FF Hoyer, AE Meerwaldt, MMT van Leent, ML Senders, ... Circulation: Cardiovascular Imaging 13 (10), e010586, 2020 | 38 | 2020 |
A modular approach toward producing nanotherapeutics targeting the innate immune system MMT van Leent, AE Meerwaldt, A Berchouchi, YC Toner, ME Burnett, ... Science advances 7 (10), eabe7853, 2021 | 22 | 2021 |
Conservation and divergence within the clathrin interactome of Trypanosoma cruzi LC Kalb, YCA Frederico, C Boehm, CMN Moreira, MJ Soares, MC Field Scientific Reports 6 (1), 31212, 2016 | 22 | 2016 |
Clathrin expression in Trypanosoma cruzi LC Kalb, YC Antunes Frederico, CM Batista, I Eger, SP Fragoso, ... BMC cell biology 15, 1-11, 2014 | 20 | 2014 |
Systematically evaluating DOTATATE and FDG as PET immuno-imaging tracers of cardiovascular inflammation YC Toner, AA Ghotbi, S Naidu, K Sakurai, MMT van Leent, S Jordan, ... Scientific reports 12 (1), 6185, 2022 | 18 | 2022 |
Resolving sepsis-induced immunoparalysis via trained immunity by targeting interleukin-4 to myeloid cells DP Schrijver, RJ Röring, J Deckers, A de Dreu, YC Toner, G Prevot, ... Nature Biomedical Engineering 7 (9), 1097-1112, 2023 | 9 | 2023 |
LAB Joosten, A. van Elsas, ZA Fayad, A. Rialdi, D. Torre, E. Guccione, J. Ochando, MG Netea, AW Griffioen and WJM Mulder B Priem, MMT van Leent, AJP Teunissen, AM Sofias, VP Mourits, ... Cell 183, 786-801, 2020 | 9 | 2020 |
Multimodal imaging of bacterial-host interface in mice and piglets with Staphylococcus aureus endocarditis P Panizzi, M Krohn-Grimberghe, E Keliher, YX Ye, J Grune, ... Science translational medicine 12 (568), eaay2104, 2020 | 8 | 2020 |
Multiparametric immunoimaging maps inflammatory signatures in murine myocardial infarction models A Maier, YC Toner, J Munitz, NAT Sullivan, K Sakurai, AE Meerwaldt, ... Basic to Translational Science 8 (7), 801-816, 2023 | 6 | 2023 |
Tumor targeting by αvβ3-integrin-specific lipid nanoparticles occurs via phagocyte hitchhiking, ACS Nano 14 (2020) 7832–7846 AM Sofias, YC Toner, AE Meerwaldt, MMT van Leent, G Soultanidis, ... | 6 | |
LAB Joosten, MG Netea, J. Ochando, ZA Fayad, C. Pérez-Medina, WJM Mulder, AJP Teunissen MMT van Leent, AE Meerwaldt, A Berchouchi, YC Toner, ME Burnett, ... Sci. Adv 7, 2021 | 5 | 2021 |
Employing nanobodies for immune landscape profiling by PET imaging in mice AJP Teunissen, OB Abousaway, J Munitz, MMT van Leent, YC Toner, ... STAR protocols 2 (2), 100434, 2021 | 2 | 2021 |
In vivo imaging of cerebral glucose metabolism informs on subacute to chronic post-stroke tissue status – A pilot study combining PET and deuterium metabolic … AE Meerwaldt, M Straathof, W Oosterveld, CL van Heijningen, ... Journal of Cerebral Blood Flow & Metabolism 43 (5), 778-790, 2023 | 1 | 2023 |