| The value of antimicrobial peptides in the age of resistance M Magana, M Pushpanathan, AL Santos, L Leanse, M Fernandez, ... The Lancet Infectious Diseases 20 (9), e216-e230, 2020 | 702 | 2020 |
| Shifting from the single to the multitarget paradigm in drug discovery JL Medina-Franco, MA Giulianotti, GS Welmaker, RA Houghten Drug discovery today 18 (9-10), 495-501, 2013 | 498 | 2013 |
| Integrating virtual screening and combinatorial chemistry for accelerated drug discovery F López-Vallejo, T Caulfield, K Martínez-Mayorga, M A Giulianotti, A Nefzi, ... Combinatorial Chemistry & High Throughput Screening 14 (6), 475-487, 2011 | 183 | 2011 |
| Characterization of Activity Landscapes Using 2D and 3D Similarity Methods: Consensus Activity Cliffs JL Medina-Franco, K Martínez-Mayorga, A Bender, RM Marín, ... Journal of chemical information and modeling 49 (2), 477-491, 2009 | 168 | 2009 |
| Visualization of the chemical space in drug discovery JL Medina-Franco, K Martínez-Mayorga, MA Giulianotti, RA Houghten, ... Current Computer-Aided Drug Design 4 (4), 322-333, 2008 | 168 | 2008 |
| Chemoinformatic analysis of combinatorial libraries, drugs, natural products, and molecular libraries small molecule repository N Singh, R Guha, MA Giulianotti, C Pinilla, RA Houghten, ... Journal of chemical information and modeling 49 (4), 1010-1024, 2009 | 166 | 2009 |
| Expanding the medicinally relevant chemical space with compound libraries F López-Vallejo, MA Giulianotti, RA Houghten, JL Medina-Franco Drug discovery today 17 (13-14), 718-726, 2012 | 159 | 2012 |
| Strategies for the use of mixture-based synthetic combinatorial libraries: scaffold ranking, direct testing in vivo, and enhanced deconvolution by computational methods RA Houghten, C Pinilla, MA Giulianotti, JR Appel, CT Dooley, A Nefzi, ... Journal of combinatorial chemistry 10 (1), 3-19, 2008 | 143 | 2008 |
| Structure–activity relationships of benzimidazole derivatives as antiparasitic agents: dual activity-difference (DAD) maps J Pérez-Villanueva, R Santos, A Hernández-Campos, MA Giulianotti, ... MedChemComm 2 (1), 44-49, 2011 | 98 | 2011 |
| Combinatorial libraries as a tool for the discovery of novel, broad-spectrum antibacterial agents targeting the ESKAPE pathogens R Fleeman, TM LaVoi, RG Santos, A Morales, A Nefzi, GS Welmaker, ... Journal of medicinal chemistry 58 (8), 3340-3355, 2015 | 94 | 2015 |
| HTS by NMR of combinatorial libraries: a fragment-based approach to ligand discovery B Wu, Z Zhang, R Noberini, E Barile, M Giulianotti, C Pinilla, RA Houghten, ... Chemistry & biology 20 (1), 19-33, 2013 | 86 | 2013 |
| A similarity‐based data‐fusion approach to the visual characterization and comparison of compound databases JL Medina‐Franco, GM Maggiora, MA Giulianotti, C Pinilla, RA Houghten Chemical Biology & Drug Design 70 (5), 393-412, 2007 | 81 | 2007 |
| Identification of beryllium-dependent peptides recognized by CD4+ T cells in chronic beryllium disease MT Falta, C Pinilla, DG Mack, AN Tinega, F Crawford, M Giulianotti, ... Journal of Experimental Medicine 210 (7), 1403-1418, 2013 | 78 | 2013 |
| Towards a systematic characterization of the antiprotozoal activity landscape of benzimidazole derivatives J Pérez-Villanueva, R Santos, A Hernández-Campos, MA Giulianotti, ... Bioorganic & medicinal chemistry 18 (21), 7380-7391, 2010 | 76 | 2010 |
| Redundancy in antigen-presenting function of the HLA-DR and-DQ molecules in the multiple sclerosis-associated HLA-DR2 haplotype M Sospedra, PA Muraro, I Stefanová, Y Zhao, K Chung, Y Li, M Giulianotti, ... The Journal of Immunology 176 (3), 1951-1961, 2006 | 71 | 2006 |
| Identification of two novel, potent, low-liability antinociceptive compounds from the direct in vivo screening of a large mixture-based combinatorial library KJ Reilley, M Giulianotti, CT Dooley, A Nefzi, JP McLaughlin, ... The AAPS journal 12 (3), 318-329, 2010 | 65 | 2010 |
| Discovery of novel inhibitors of a disintegrin and metalloprotease 17 (ADAM17) using glycosylated and non-glycosylated substrates D Minond, M Cudic, N Bionda, M Giulianotti, L Maida, RA Houghten, ... Journal of Biological Chemistry 287 (43), 36473-36487, 2012 | 63 | 2012 |
| Tissue chips in space: modeling human diseases in microgravity LA Low, MA Giulianotti Pharmaceutical research 37 (1), 1-6, 2020 | 52 | 2020 |
| Synthesis of cyclic peptides through direct aminolysis of peptide thioesters catalyzed by imidazole in aqueous organic solutions Y Li, A Yongye, M Giulianotti, K Martinez-Mayorga, Y Yu, RA Houghten Journal of combinatorial chemistry 11 (6), 1066-1072, 2009 | 52 | 2009 |
| Solid-phase synthesis of trisubstituted 2-imidazolidones and 2-imidazolidinethiones A Nefzi, JM Ostresh, M Giulianotti, RA Houghten Journal of Combinatorial Chemistry 1 (3), 195-198, 1999 | 51 | 1999 |
