Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy D Finzi, J Blankson, JD Siliciano, JB Margolick, K Chadwick, T Pierson, ... Nature medicine 5 (5), 512-517, 1999 | 2674 | 1999 |
Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure YC Ho, L Shan, NN Hosmane, J Wang, SB Laskey, DIS Rosenbloom, ... Cell 155 (3), 540-551, 2013 | 1477 | 2013 |
The challenge of viral reservoirs in HIV-1 infection JN Blankson, D Persaud, RF Siliciano Annual review of medicine 53 (1), 557-593, 2002 | 904 | 2002 |
Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation L Shan, K Deng, NS Shroff, CM Durand, SA Rabi, HC Yang, H Zhang, ... Immunity 36 (3), 491-501, 2012 | 846 | 2012 |
A quantitative approach for measuring the reservoir of latent HIV-1 proviruses KM Bruner, Z Wang, FR Simonetti, AM Bender, KJ Kwon, S Sengupta, ... Nature 566 (7742), 120-125, 2019 | 553 | 2019 |
Isolation and characterization of replication-competent human immunodeficiency virus type 1 from a subset of elite suppressors JN Blankson, JR Bailey, S Thayil, HC Yang, K Lassen, J Lai, SK Gandhi, ... Journal of virology 81 (5), 2508-2518, 2007 | 343 | 2007 |
Maintenance of viral suppression in HIV-1–infected HLA-B*57+ elite suppressors despite CTL escape mutations JR Bailey, TM Williams, RF Siliciano, JN Blankson The Journal of experimental medicine 203 (5), 1357-1369, 2006 | 340 | 2006 |
Rapid quantification of the latent reservoir for HIV-1 using a viral outgrowth assay GM Laird, EE Eisele, SA Rabi, J Lai, S Chioma, JN Blankson, JD Siliciano, ... PLoS pathogens 9 (5), e1003398, 2013 | 300 | 2013 |
HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study TJ Henrich, H Hatano, O Bacon, LE Hogan, R Rutishauser, A Hill, ... PLoS medicine 14 (11), e1002417, 2017 | 232 | 2017 |
Neutralizing antibodies do not mediate suppression of human immunodeficiency virus type 1 in elite suppressors or selection of plasma virus variants in patients on highly … JR Bailey, KG Lassen, HC Yang, TC Quinn, SC Ray, JN Blankson, ... Journal of virology 80 (10), 4758-4770, 2006 | 223 | 2006 |
Biphasic Decay of Latently Infected CD4+ T Cells in Acute Human Immunodeficiency Virus Type 1 Infection JN Blankson, D Finzi, TC Pierson, BP Sabundayo, K Chadwick, ... The Journal of infectious diseases 182 (6), 1636-1642, 2000 | 208 | 2000 |
Characterization of chemokine receptor utilization of viruses in the latent reservoir for human immunodeficiency virus type 1 T Pierson, TL Hoffman, J Blankson, D Finzi, K Chadwick, JB Margolick, ... Journal of virology 74 (17), 7824-7833, 2000 | 199 | 2000 |
HIV and HCV activate the inflammasome in monocytes and macrophages via endosomal Toll-like receptors without induction of type 1 interferon MA Chattergoon, R Latanich, J Quinn, ME Winter, RW Buckheit 3rd, ... PLoS pathogens 10 (5), e1004082, 2014 | 191 | 2014 |
SARS-CoV-2 mRNA vaccines induce broad CD4+ T cell responses that recognize SARS-CoV-2 variants and HCoV-NL63 BA Woldemeskel, CC Garliss, JN Blankson The Journal of clinical investigation 131 (10), 2021 | 187 | 2021 |
A simian immunodeficiency virus-infected macaque model to study viral reservoirs that persist during highly active antiretroviral therapy JB Dinoso, SA Rabi, JN Blankson, L Gama, JL Mankowski, RF Siliciano, ... Journal of virology 83 (18), 9247-9257, 2009 | 178 | 2009 |
Relationships of PBMC microRNA expression, plasma viral load, and CD4+ T-cell count in HIV-1-infected elite suppressors and viremic patients KW Witwer, AK Watson, JN Blankson, JE Clements Retrovirology 9, 1-15, 2012 | 171 | 2012 |
Preservation of FoxP3+ regulatory T cells in the peripheral blood of human immunodeficiency virus type 1-infected elite suppressors correlates with low CD4+ T-cell activation AJ Chase, HC Yang, H Zhang, JN Blankson, RF Siliciano Journal of virology 82 (17), 8307-8315, 2008 | 165 | 2008 |
Hospitalization rates and reasons among HIV elite controllers and persons with medically controlled HIV infection TA Crowell, KA Gebo, JN Blankson, PT Korthuis, BR Yehia, RM Rutstein, ... The Journal of infectious diseases 211 (11), 1692-1702, 2015 | 151 | 2015 |
Elucidating the elite: mechanisms of control in HIV-1 infection KA O’Connell, JR Bailey, JN Blankson Trends in pharmacological sciences 30 (12), 631-637, 2009 | 151 | 2009 |
The BNT162b2 mRNA vaccine elicits robust humoral and cellular immune responses in people living with human immunodeficiency virus (HIV) BA Woldemeskel, AH Karaba, CC Garliss, EJ Beck, KH Wang, ... Clinical Infectious Diseases 74 (7), 1268-1270, 2022 | 142 | 2022 |