| TNFα and IFNγ synergistically enhance transcriptional activation of CXCL10 in human airway smooth muscle cells via STAT-1, NF-κB, and the transcriptional coactivator CREB … DL Clarke, RL Clifford, S Jindarat, D Proud, L Pang, M Belvisi, AJ Knox Journal of Biological Chemistry 285 (38), 29101-29110, 2010 | 173 | 2010 |
| Inhalation of diesel exhaust and allergen alters human bronchial epithelium DNA methylation RL Clifford, MJ Jones, JL MacIsaac, LM McEwen, SJ Goodman, ... Journal of Allergy and Clinical Immunology 139 (1), 112-121, 2017 | 146 | 2017 |
| Novel regulation of vascular endothelial growth factor-A (VEGF-A) by transforming growth factor β1: requirement for Smads, β-catenin, and GSK3β RL Clifford, K Deacon, AJ Knox Journal of Biological Chemistry 283 (51), 35337-35353, 2008 | 137 | 2008 |
| Vitamin D–a new treatment for airway remodelling in asthma? RL Clifford, AJ Knox British journal of pharmacology 158 (6), 1426-1428, 2009 | 73 | 2009 |
| Pro-inflammatory and immunomodulatory functions of airway smooth muscle: emerging concepts YC Xia, NS Redhu, LM Moir, C Koziol-White, AJ Ammit, L Al-Alwan, ... Pulmonary pharmacology & therapeutics 26 (1), 64-74, 2013 | 66 | 2013 |
| CXCL8 histone H3 acetylation is dysfunctional in airway smooth muscle in asthma: regulation by BET RL Clifford, JK Patel, AE John, AL Tatler, L Mazengarb, CE Brightling, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 308 (9 …, 2015 | 65 | 2015 |
| Abnormal histone methylation is responsible for increased vascular endothelial growth factor 165a secretion from airway smooth muscle cells in asthma RL Clifford, AE John, CE Brightling, AJ Knox The Journal of Immunology 189 (2), 819-831, 2012 | 62 | 2012 |
| Amplification of TGFβ induced ITGB6 gene transcription may promote pulmonary fibrosis AL Tatler, AT Goodwin, O Gbolahan, G Saini, J Porte, AE John, RL Clifford, ... PloS one 11 (8), e0158047, 2016 | 44 | 2016 |
| Epigenetic changes in airway smooth muscle as a driver of airway inflammation and remodeling in asthma KA Kaczmarek, RL Clifford, AJ Knox Chest 155 (4), 816-824, 2019 | 38 | 2019 |
| Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD RL Clifford, N Fishbane, J Patel, JL MacIsaac, LM McEwen, AJ Fisher, ... Clinical epigenetics 10, 1-14, 2018 | 38 | 2018 |
| Epigenetics and miRNA emerge as key regulators of smooth muscle cell phenotype and function RL Clifford, CA Singer, AE John Pulmonary pharmacology & therapeutics 26 (1), 75-85, 2013 | 34 | 2013 |
| Ciclesonide inhibits TNFα-and IL-1β-induced monocyte chemotactic protein-1 (MCP-1/CCL2) secretion from human airway smooth muscle cells JK Patel, RL Clifford, K Deacon, AJ Knox American Journal of Physiology-Lung Cellular and Molecular Physiology 302 (8 …, 2012 | 30 | 2012 |
| Epigenetic dysregulation of interleukin 8 (CXCL8) hypersecretion in cystic fibrosis airway epithelial cells A Poghosyan, JK Patel, RL Clifford, AJ Knox Biochemical and biophysical research communications 476 (4), 431-437, 2016 | 15 | 2016 |
| Transcriptional regulation of inflammatory genes associated with severe asthma R L Clifford, W R Coward, A J Knox, A E John Current pharmaceutical design 17 (7), 653-666, 2011 | 15 | 2011 |
| Future bronchodilator therapy: a bitter pill to swallow? RL Clifford, AJ Knox American Journal of Physiology-Lung Cellular and Molecular Physiology 303 …, 2012 | 13 | 2012 |
| Predominant DNMT and TET mediate effects of allergen on the human bronchial epithelium in a controlled air pollution exposure study H Li, MH Ryu, CF Rider, W Tse, RL Clifford, MJ Aristizabal, W Wen, ... Journal of Allergy and Clinical Immunology 147 (5), 1671-1682, 2021 | 12 | 2021 |
| Airway epithelial cell isolation techniques affect DNA methylation profiles with consequences for analysis of asthma related perturbations to DNA methylation RL Clifford, J Patel, JL MacIsaac, LM McEwen, SR Johnson, D Shaw, ... Scientific Reports 9 (1), 14409, 2019 | 11 | 2019 |
| TWIST1 DNA methylation is a cell marker of airway and parenchymal lung fibroblasts that are differentially methylated in asthma RL Clifford, CX Yang, N Fishbane, J Patel, JL MacIsaac, LM McEwen, ... Clinical Epigenetics 12, 1-20, 2020 | 9 | 2020 |
| Abnormal histone methylation is responsible for increased VEGF165a secretion from airway smooth muscle cells in asthma RL Clifford, AE John, CE Brightling, AJ Knox Journal of immunology (Baltimore, Md.: 1950) 189 (2), 819, 2012 | 5 | 2012 |
| DNA methylation of fibroblast phenotypes and contributions to lung fibrosis P Rajasekar, J Patel, RL Clifford Cells 10 (8), 1977, 2021 | 4 | 2021 |
