| Transmission of tauopathy strains is independent of their isoform composition Z He, JD McBride, H Xu, L Changolkar, S Kim, B Zhang, S Narasimhan, ... Nature communications 11 (1), 7, 2020 | 111 | 2020 |
| PERK activation mitigates tau pathology in vitro and in vivo J Bruch, H Xu, TW Rösler, A De Andrade, PH Kuhn, SF Lichtenthaler, ... EMBO molecular medicine 9 (3), 371-384, 2017 | 108 | 2017 |
| α-Synuclein modulates tau spreading in mouse brains F Bassil, ES Meymand, HJ Brown, H Xu, TO Cox, S Pattabhiraman, ... Journal of Experimental Medicine 218 (1), e20192193, 2020 | 56 | 2020 |
| Tau silencing by siRNA in the P301S mouse model of tauopathy H Xu, T W Rosler, T Carlsson, A de Andrade, O Fiala, M Hollerhage, ... Current gene therapy 14 (5), 343-351, 2014 | 54 | 2014 |
| Memory deficits correlate with tau and spine pathology in P301S MAPT transgenic mice H Xu, TW Rösler, T Carlsson, A de Andrade, J Bruch, M Höllerhage, ... Neuropathology and applied neurobiology 40 (7), 833-843, 2014 | 50 | 2014 |
| GFP-mutant human tau transgenic mice develop tauopathy following CNS injections of Alzheimer's brain-derived pathological tau or synthetic mutant human tau fibrils GS Gibbons, RA Banks, B Kim, H Xu, L Changolkar, SN Leight, ... Journal of Neuroscience 37 (47), 11485-11494, 2017 | 42 | 2017 |
| In vitro amplification of pathogenic tau conserves disease-specific bioactive characteristics H Xu, M O’Reilly, GS Gibbons, L Changolkar, JD McBride, DM Riddle, ... Acta neuropathologica 141, 193-215, 2021 | 39 | 2021 |
| Post-translational modifications of soluble α-synuclein regulate the amplification of pathological α-synuclein S Zhang, R Zhu, B Pan, H Xu, MF Olufemi, RJ Gathagan, Y Li, L Zhang, ... Nature neuroscience 26 (2), 213-225, 2023 | 38 | 2023 |
| Fluent molecular mixing of Tau isoforms in Alzheimer’s disease neurofibrillary tangles AJ Dregni, P Duan, H Xu, L Changolkar, N El Mammeri, VMY Lee, ... Nature communications 13 (1), 2967, 2022 | 36 | 2022 |
| Chronic consumption of Annona muricata juice triggers and aggravates cerebral tau phosphorylation in wild‐type and MAPT transgenic mice R Rottscholl, M Haegele, B Jainsch, H Xu, G Respondek, M Höllerhage, ... Journal of neurochemistry 139 (4), 624-639, 2016 | 33 | 2016 |
| Identification of a nanomolar affinity α-synuclein fibril imaging probe by ultra-high throughput in silico screening JJ Ferrie, Z Lengyel-Zhand, B Janssen, MG Lougee, S Giannakoulias, ... Chemical Science 11 (47), 12746-12754, 2020 | 32 | 2020 |
| Microglial transcriptome analysis in the rNLS8 mouse model of TDP-43 proteinopathy reveals discrete expression profiles associated with neurodegenerative progression and recovery M Hunter, KJ Spiller, MA Dominique, H Xu, FW Hunter, TC Fang, ... Acta Neuropathologica Communications 9, 1-19, 2021 | 29 | 2021 |
| Mitochondrial complex 1 inhibition increases 4-repeat isoform tau by SRSF2 upregulation J Bruch, H Xu, A De Andrade, G Höglinger PloS one 9 (11), e113070, 2014 | 24 | 2014 |
| Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer’s disease GS Gibbons, SJ Kim, Q Wu, DM Riddle, SN Leight, L Changolkar, H Xu, ... Molecular Neurodegeneration 15, 1-19, 2020 | 23 | 2020 |
| TRIM11 protects against tauopathies and is down-regulated in Alzheimer’s disease ZY Zhang, DS Harischandra, R Wang, S Ghaisas, JY Zhao, ... Science 381 (6656), eadd6696, 2023 | 20 | 2023 |
| Piericidin A aggravates Tau pathology in P301S transgenic mice M Höllerhage, R Deck, A De Andrade, G Respondek, H Xu, TW Rösler, ... PLoS One 9 (12), e113557, 2014 | 18 | 2014 |
| A microtubule stabilizer ameliorates protein pathogenesis and neurodegeneration in mouse models of repetitive traumatic brain injury X Zhao, W Zeng, H Xu, Z Sun, Y Hu, B Peng, JD McBride, J Duan, J Deng, ... Science translational medicine 15 (713), eabo6889, 2023 | 4 | 2023 |
| In Vitro Amplification of Pathogenic Tau Seeds from Neurodegenerative Disease Patient Brains H Xu, VMY Lee Alzheimer’s Disease: Methods and Protocols, 279-292, 2022 | 1 | 2022 |
| MSUT2 regulates tau spreading via adenosinergic signaling mediated ASAP1 pathway in neurons H Xu, Q Qiu, P Hu, K Hoxha, E Jang, M O’Reilly, C Kim, Z He, N Marotta, ... Acta Neuropathologica 147 (1), 55, 2024 | | 2024 |
| Modeling tauopathy using human‐like pathogenic tau seeds H Xu, Center for Neurodegenerative Disease Research Alzheimer's & Dementia 17, e053860, 2021 | | 2021 |
