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Maghnus O'Seaghdha
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Blocking neuronal signaling to immune cells treats streptococcal invasive infection
FA Pinho-Ribeiro, B Baddal, R Haarsma, M O’Seaghdha, NJ Yang, ...
Cell 173 (5), 1083-1097. e22, 2018
3192018
Staphylococcus aureus protein A activates TNFR1 signaling through conserved IgG binding domains
MI Gómez, M O'Seaghdha, M Magargee, TJ Foster, AS Prince
Journal of biological chemistry 281 (29), 20190-20196, 2006
2052006
Staphylococcus aureus protein A binds to osteoblasts and triggers signals that weaken bone in osteomyelitis
T Claro, A Widaa, M O'Seaghdha, H Miajlovic, TJ Foster, FJ O'Brien, ...
PloS one 6 (4), e18748, 2011
2002011
Interaction of human complement with Sbi, a staphylococcal immunoglobulin-binding protein: indications of a novel mechanism of complement evasion by Staphylococcus aureus
JD Burman, E Leung, KL Atkins, MN O'Seaghdha, L Lango, P Bernadó, ...
Journal of Biological Chemistry 283 (25), 17579-17593, 2008
1942008
Staphylococcus aureus activates type I IFN signaling in mice and humans through the Xr repeated sequences of protein A
FJ Martin, MI Gomez, DM Wetzel, G Memmi, M O’Seaghdha, G Soong, ...
The Journal of clinical investigation 119 (7), 1931-1939, 2009
1882009
Staphylococcus aureus protein A binding to von Willebrand factor A1 domain is mediated by conserved IgG binding regions
M O'Seaghdha, CJ van Schooten, SW Kerrigan, J Emsley, GJ Silverman, ...
The FEBS journal 273 (21), 4831-4841, 2006
1722006
Streptolysin O and its Co-Toxin NAD-glycohydrolase Protect Group A Streptococcus from Xenophagic Killing
M O'Seaghdha, MR Wessels
PLoS pathogens 9 (6), e1003394, 2013
1352013
Staphylococcus aureus protein A activates TACE through EGFR‐dependent signaling
MI Gómez, MO Seaghdha, AS Prince
The EMBO journal 26 (3), 701-709, 2007
1332007
NAD+-Glycohydrolase Promotes Intracellular Survival of Group A Streptococcus
O Sharma, M O’Seaghdha, JJ Velarde, MR Wessels
PLoS pathogens 12 (3), e1005468, 2016
412016
Inhibition of Inflammasome-Dependent Interleukin 1β Production by Streptococcal NAD+-Glycohydrolase: Evidence for Extracellular Activity
D Hancz, E Westerlund, B Bastiat-Sempe, O Sharma, C Valfridsson, ...
MBio 8 (4), 10.1128/mbio. 00756-17, 2017
372017
Binding of NAD+-Glycohydrolase to Streptolysin O Stabilizes Both Toxins and Promotes Virulence of Group A Streptococcus
JJ Velarde, M O’Seaghdha, B Baddal, B Bastiat-Sempe, MR Wessels
MBio 8 (5), 10.1128/mbio. 01382-17, 2017
302017
A high throughput microphysiological model of prosthetic valve endocarditis for investigating factors that influence bacterial adhesion under fluid shear stress
LD Rubio, KA McFarland, M O'Seaghdha, C Williams
Biochemical and Biophysical Research Communications 686, 149155, 2023
2023
Staphylococcal Protein A, Panton-Valentine Leukocidin and Coagulase Aggravate the Bone Loss and Bone Destruction in Osteomyelitis (vol 32, pg 322, 2013)
T Claro, A Widaa, M O'Seaghdha, H Miajlovic, TJ Foster, FJ O'Brien, ...
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY: Erratum 35 (3), 1252-1252, 2015
2015
Molecular Analysis of the Interaction Between Protein A of Staphylococcus Aureus and Von Willebrand Factor
MNO Séaghdha
Trinity College Dublin, 2007
2007
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