Elexacaftor is a CFTR potentiator and acts synergistically with ivacaftor during acute and chronic treatment CA Shaughnessy, PL Zeitlin, PE Bratcher Scientific reports 11 (1), 19810, 2021 | 52 | 2021 |
Functional characterization and osmoregulatory role of the Na-K-2Cl cotransporter in the gill of sea lamprey (Petromyzon marinus), a basal vertebrate CA Shaughnessy, SD McCormick Am J Physiol Regul Integr Comp Physiol 318, R17-R29, 2020 | 28 | 2020 |
Osmoregulatory role of the intestine in the sea lamprey (Petromyzon marinus) A Barany, CA Shaughnessy, J Fuentes, JM Mancera, SD McCormick American Journal of Physiology-Regulatory, Integrative and Comparative …, 2020 | 24 | 2020 |
IL-13–programmed airway tuft cells produce PGE2, which promotes CFTR-dependent mucociliary function ME Kotas, CM Moore, JG Gurrola, SD Pletcher, AN Goldberg, R Alvarez, ... JCI insight 7 (13), 2022 | 23 | 2022 |
11-Deoxycortisol controls hydromineral balance in the most basal osmoregulating vertebrate, sea lamprey (Petromyzon marinus) CA Shaughnessy, A Barany, SD McCormick Scientific Reports 10 (1), 12148, 2020 | 20 | 2020 |
Interaction of osmoregulatory and acid–base compensation in white sturgeon (Acipenser transmontanus) during exposure to aquatic hypercarbia and elevated … CA Shaughnessy, DW Baker, CJ Brauner, JD Morgan, JS Bystriansky The Journal of experimental biology 218 (17), 2712-2719, 2015 | 20 | 2015 |
Reduced thermal tolerance during salinity acclimation in brook trout (Salvelinus fontinalis) can be rescued by prior treatment with cortisol CA Shaughnessy, SD McCormick Journal of Experimental Biology 221 (6), jeb169557, 2018 | 17 | 2018 |
Tissue and salinity specific Na+/Cl− cotransporter (NCC) orthologues involved in the adaptive osmoregulation of sea lamprey (Petromyzon marinus) A Barany, CA Shaughnessy, RM Pelis, J Fuentes, JM Mancera, ... Scientific Reports 11 (1), 22698, 2021 | 14 | 2021 |
11-Deoxycortisol is a stress responsive and gluconeogenic hormone in a jawless vertebrate, the sea lamprey (Petromyzon marinus) CA Shaughnessy, SD McCormick Journal of Experimental Biology 224 (11), jeb241943, 2021 | 13 | 2021 |
Molecular mechanisms of Cl− transport in fishes: New insights and their evolutionary context CA Shaughnessy, JP Breves Journal of Experimental Zoology Part A: Ecological and Integrative …, 2021 | 13 | 2021 |
Upper Thermal Tolerance and Heat Shock Protein Response of Juvenile American Shad (Alosa sapidissima) SM Bayse, CA Shaughnessy, AM Regish, SD McCormick Estuaries and coasts 43 (1), 182-188, 2020 | 9 | 2020 |
Effect of apical chloride concentration on the measurement of responses to CFTR modulation in airway epithelia cultured from nasal brushings PE Bratcher, S Yadav, CA Shaughnessy, IM Thornell, PL Zeitlin Physiological reports 8 (19), e14603, 2020 | 8 | 2020 |
A basal actinopterygian melanocortin receptor: Molecular and functional characterization of an Mc2r ortholog from the Senegal bichir (Polypterus senegalus) CA Shaughnessy, MF Jensen, RM Dores General and Comparative Endocrinology 328, 114105, 2022 | 6 | 2022 |
Receptor-mediated activation of CFTR via prostaglandin signaling pathways in the airway CA Shaughnessy, S Yadav, PE Bratcher, PL Zeitlin American Journal of Physiology-Lung Cellular and Molecular Physiology 322 (3 …, 2022 | 6 | 2022 |
Structure/function studies on the activation motif of two non-mammalian Mrap1 orthologs, and observations on the phylogeny of Mrap1, including a novel characterization of an … RM Dores, G McKinley, A Meyers, M Martin, CA Shaughnessy Biomolecules 12 (11), 1681, 2022 | 4 | 2022 |
Human melanocortin-2 receptor: Identifying a role for residues in the TM4, EC2, and TM5 domains in activation and trafficking as a result of co-expression with the accessory … PV Davis, CA Shaughnessy, RM Dores Biomolecules 12 (10), 1422, 2022 | 4 | 2022 |
Corticosteroid control of Na+/K+-ATPase in the intestine of the sea lamprey (Petromyzon marinus) A Barany, CA Shaughnessy, SD McCormick General and Comparative Endocrinology 307, 113756, 2021 | 4 | 2021 |
Net benefit of ivacaftor during prolonged tezacaftor/elexacaftor exposure in vitro CA Shaughnessy, PL Zeitlin, PE Bratcher Journal of Cystic Fibrosis 21 (4), 637-643, 2022 | 3 | 2022 |
Downregulation of epithelial sodium channel (ENaC) activity in human airway epithelia after low temperature incubation S Yadav, CA Shaughnessy, PL Zeitlin, PE Bratcher BMJ Open Respiratory Research 8 (1), e000861, 2021 | 3 | 2021 |
Trends in the evolution of the elasmobranch melanocortin-2 receptor: Insights from structure/function studies on the activation of whale shark Mc2r BE Hoglin, MV Miner, U Erdenebayar, CA Shaughnessy, RM Dores General and Comparative Endocrinology 338, 114278, 2023 | 2 | 2023 |