| Thermal proximity coaggregation for system-wide profiling of protein complex dynamics in cells CSH Tan, KD Go, X Bisteau, L Dai, CH Yong, N Prabhu, MB Ozturk, ... Science 359 (6380), 1170-1177, 2018 | 194 | 2018 |
| Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay JM Dziekan, H Yu, D Chen, L Dai, G Wirjanata, A Larsson, N Prabhu, ... Science translational medicine 11 (473), eaau3174, 2019 | 181 | 2019 |
| Exosomes as potential sources of biomarkers in colorectal cancer Y Xiao, J Zhong, B Zhong, J Huang, L Jiang, Y Jiang, J Yuan, J Sun, L Dai, ... Cancer letters 476, 13-22, 2020 | 148 | 2020 |
| Modulation of protein-interaction states through the cell cycle L Dai, T Zhao, X Bisteau, W Sun, N Prabhu, YT Lim, RM Sobota, P Kaldis, ... Cell 173 (6), 1481-1494. e13, 2018 | 137 | 2018 |
| Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1 P Luo, D Liu, Q Zhang, F Yang, YK Wong, F Xia, J Zhang, J Chen, Y Tian, ... Acta Pharmaceutica Sinica B 12 (5), 2300-2314, 2022 | 102 | 2022 |
| miR‐223 suppresses differentiation of tumor‐induced CD11b+Gr1+myeloid‐derived suppressor cells from bone marrow cells Q Liu, M Zhang, X Jiang, Z Zhang, L Dai, S Min, X Wu, Q He, J Liu, ... International journal of cancer 129 (11), 2662-2673, 2011 | 97 | 2011 |
| Horizontal cell biology: monitoring global changes of protein interaction states with the proteome-wide cellular thermal shift assay (CETSA) L Dai, N Prabhu, LY Yu, S Bacanu, AD Ramos, P Nordlund Annual review of biochemistry 88, 383-408, 2019 | 91 | 2019 |
| Cellular thermal shift assay for the identification of drug–target interactions in the Plasmodium falciparum proteome JM Dziekan, G Wirjanata, L Dai, KD Go, H Yu, YT Lim, L Chen, LC Wang, ... Nature protocols 15 (6), 1881-1921, 2020 | 81 | 2020 |
| Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality M Kitagawa, PJ Liao, KH Lee, J Wong, SC Shang, N Minami, ... Nature communications 8 (1), 2200, 2017 | 72 | 2017 |
| Antigen presentation by dendritic cells in tumors is disrupted by altered metabolism that involves pyruvate kinase M2 and its interaction with SOCS3 Z Zhang, Q Liu, Y Che, X Yuan, L Dai, B Zeng, G Jiao, Y Zhang, X Wu, ... Cancer research 70 (1), 89-98, 2010 | 50 | 2010 |
| An efficient proteome-wide strategy for discovery and characterization of cellular nucleotide-protein interactions YT Lim, N Prabhu, L Dai, KD Go, D Chen, L Sreekumar, L Egeblad, ... PLoS One 13 (12), e0208273, 2018 | 49 | 2018 |
| METTL7B is required for cancer cell proliferation and tumorigenesis in non-small cell lung cancer D Liu, W Li, F Zhong, J Yin, W Zhou, S Li, X Sun, J Xu, G Li, Y Wen, ... Frontiers in pharmacology 11, 178, 2020 | 42 | 2020 |
| CETSA in integrated proteomics studies of cellular processes N Prabhu, L Dai, P Nordlund Current opinion in chemical biology 54, 54-62, 2020 | 42 | 2020 |
| Monitoring structural modulation of redox-sensitive proteins in cells with MS-CETSA W Sun, L Dai, H Yu, B Puspita, T Zhao, F Li, JL Tan, YT Lim, MW Chen, ... Redox biology 24, 101168, 2019 | 41 | 2019 |
| Celastrol mitigates inflammation in sepsis by inhibiting the PKM2-dependent Warburg effect P Luo, Q Zhang, TY Zhong, JY Chen, JZ Zhang, Y Tian, LH Zheng, F Yang, ... Military Medical Research 9 (1), 22, 2022 | 36 | 2022 |
| Photothermal nanozymatic nanoparticles induce ferroptosis and apoptosis through tumor microenvironment manipulation for cancer therapy H Yuan, P Xia, X Sun, J Ma, X Xu, C Fu, H Zhou, Y Guan, Z Li, S Zhao, ... Small 18 (41), 2202161, 2022 | 32 | 2022 |
| Capsaicin ameliorates inflammation in a TRPV1-independent mechanism by inhibiting PKM2-LDHA-mediated Warburg effect in sepsis Q Zhang, P Luo, F Xia, H Tang, J Chen, J Zhang, D Liu, Y Zhu, Y Liu, L Gu, ... Cell Chemical Biology 29 (8), 1248-1259. e6, 2022 | 30 | 2022 |
| Target identification and validation of natural products with label-free methodology: A critical review from 2005 to 2020 L Dai, Z Li, D Chen, L Jia, J Guo, T Zhao, P Nordlund Pharmacology & Therapeutics 216, 107690, 2020 | 27 | 2020 |
| LRRC19, a novel member of the leucine-rich repeat protein family, activates NF-κB and induces expression of proinflammatory cytokines L Chai, L Dai, Y Che, J Xu, G Liu, Z Zhang, R Yang Biochemical and biophysical research communications 388 (3), 543-548, 2009 | 26 | 2009 |
| CETSA interaction proteomics define specific RNA-modification pathways as key components of fluorouracil-based cancer drug cytotoxicity YY Liang, S Bacanu, L Sreekumar, AD Ramos, L Dai, M Michaelis, ... Cell Chemical Biology 29 (4), 572-585. e8, 2022 | 20 | 2022 |
Par NordlundKarolinska InstitutetVerified email at ki.se
