Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate O Cuvillier, G Pirianov, B Kleuser, PG Vanek, OA Coso, JS Gutkind, ... Nature 381 (6585), 800-803, 1996 | 1901 | 1996 |
HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P3 JR Nofer, M Van Der Giet, M Tölle, I Wolinska, K von Wnuck Lipinski, ... The Journal of clinical investigation 113 (4), 569-581, 2004 | 891 | 2004 |
Acid sphingomyelinase–ceramide system mediates effects of antidepressant drugs E Gulbins, M Palmada, M Reichel, A Lüth, C Böhmer, D Amato, CP Müller, ... Nature medicine 19 (7), 934-938, 2013 | 424 | 2013 |
Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation S Lotinun, R Kiviranta, T Matsubara, JA Alzate, L Neff, A Lüth, I Koskivirta, ... The Journal of clinical investigation 123 (2), 2013 | 353 | 2013 |
N,N-Dimethylsphingosine Is a Potent Competitive Inhibitor of Sphingosine Kinase but Not of Protein Kinase C: Modulation of Cellular Levels of Sphingosine 1 … LC Edsall, JR Van Brocklyn, O Cuvillier, B Kleuser, S Spiegel Biochemistry 37 (37), 12892-12898, 1998 | 292 | 1998 |
Hepatocyte exosomes mediate liver repair and regeneration via sphingosine-1-phosphate H Nojima, CM Freeman, RM Schuster, L Japtok, B Kleuser, MJ Edwards, ... Journal of hepatology 64 (1), 60-68, 2016 | 277 | 2016 |
Transcriptional activity of potent glucocorticoids: relevance of glucocorticoid receptor isoforms and drug metabolites I Spika, S Hammer, B Kleuser, HC Korting, M Schäfer-Korting Skin Pharmacology and Physiology 16 (3), 143-150, 2003 | 262 | 2003 |
Engineered liposomes sequester bacterial exotoxins and protect from severe invasive infections in mice BD Henry, DR Neill, KA Becker, S Gore, L Bricio-Moreno, R Ziobro, ... Nature biotechnology 33 (1), 81-88, 2015 | 230 | 2015 |
Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts J Keller, P Catala-Lehnen, AK Huebner, A Jeschke, T Heckt, A Lueth, ... Nature communications 5 (1), 5215, 2014 | 199 | 2014 |
Antidepressants act by inducing autophagy controlled by sphingomyelin–ceramide A Gulbins, F Schumacher, KA Becker, B Wilker, M Soddemann, F Boldrin, ... Molecular psychiatry 23 (12), 2324-2346, 2018 | 189 | 2018 |
Acid sphingomyelinase inhibitors normalize pulmonary ceramide and inflammation in cystic fibrosis KA Becker, J Riethmüller, A Lüth, G Döring, B Kleuser, E Gulbins American journal of respiratory cell and molecular biology 42 (6), 716-724, 2010 | 189 | 2010 |
Cyproterone acetate loading to lipid nanoparticles for topical acne treatment: particle characterisation and skin uptake J Štecová, W Mehnert, T Blaschke, B Kleuser, R Sivaramakrishnan, ... Pharmaceutical research 24, 991-1000, 2007 | 178 | 2007 |
1α, 25-Dihydroxyvitamin D3 protects human keratinocytes from apoptosis by the formation of sphingosine-1-phosphate M Manggau, DS Kim, L Ruwisch, R Vogler, M Schäfer-Korting, B Kleuser, ... Journal of Investigative Dermatology 117 (5), 1241-1249, 2001 | 173 | 2001 |
1α,25-Dihydroxyvitamin D3 Inhibits Programmed Cell Death in HL-60 Cells by Activation of Sphingosine Kinase B Kleuser, O Cuvillier, S Spiegel Cancer research 58 (9), 1817-1824, 1998 | 156 | 1998 |
Sphingosine-1-phosphate and its potentially paradoxical effects on critical parameters of cutaneous wound healing R Vogler, B Sauer, DS Kim, M Schäfer-Korting, B Kleuser Journal of Investigative Dermatology 120 (4), 693-700, 2003 | 131 | 2003 |
Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosa Y Pewzner‐Jung, S Tavakoli Tabazavareh, H Grassmé, KA Becker, ... EMBO molecular medicine 6 (9), 1205-1214, 2014 | 127 | 2014 |
17-β-estradiol inhibits transforming growth factor-β signaling and function in breast cancer cells via activation of extracellular signal-regulated kinase through the G protein … B Kleuser, D Malek, R Gust, HH Pertz, H Potteck Molecular pharmacology 74 (6), 1533-1543, 2008 | 123 | 2008 |
Skin penetration and metabolism of topical glucocorticoids in reconstructed epidermis and in excised human skin A Gysler, B Kleuser, W Sippl, K Lange, HC Korting, HD Höltje, ... Pharmaceutical research 16, 1386-1391, 1999 | 110 | 1999 |
Influences of opioids and nanoparticles on in vitro wound healing models NB Wolf, S Küchler, MR Radowski, T Blaschke, KD Kramer, G Weindl, ... European Journal of Pharmaceutics and Biopharmaceutics 73 (1), 34-42, 2009 | 105 | 2009 |
Immunomodulator FTY720 induces myofibroblast differentiation via the lysophospholipid receptor S1P3 and Smad3 signaling CD Keller, PR Gil, M Tölle, M van der Giet, J Chun, HH Radeke, ... The American journal of pathology 170 (1), 281-292, 2007 | 105 | 2007 |