ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation S Rühl, K Shkarina, B Demarco, R Heilig, JC Santos, P Broz Science 362 (6417), 956-960, 2018 | 533 | 2018 |
Extrinsic and intrinsic apoptosis activate pannexin‐1 to drive NLRP 3 inflammasome assembly KW Chen, B Demarco, R Heilig, K Shkarina, A Boettcher, CJ Farady, ... The EMBO journal 38 (10), e101638, 2019 | 315 | 2019 |
Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria JC Santos, D Boucher, LK Schneider, B Demarco, M Dilucca, K Shkarina, ... Nature communications 11 (1), 3276, 2020 | 205 | 2020 |
Caspase-8–dependent gasdermin D cleavage promotes antimicrobial defense but confers susceptibility to TNF-induced lethality B Demarco, JP Grayczyk, E Bjanes, D Le Roy, W Tonnus, ... Science advances 6 (47), eabc3465, 2020 | 147 | 2020 |
Lipid-coated zinc oxide nanoparticles as innovative ROS-generators for photodynamic therapy in cancer cells A Ancona, B Dumontel, N Garino, B Demarco, D Chatzitheodoridou, ... Nanomaterials 8 (3), 143, 2018 | 119 | 2018 |
RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signalling K Chen, B Demarco, R Heilig, S Ramos, J Grayczyk, CA Assenmacher, ... Proceedings of the National Academy of Sciences, 2021 | 79 | 2021 |
Beyond inflammasomes: emerging function of gasdermins during apoptosis and NETosis KW Chen, B Demarco, P Broz The EMBO journal 39 (2), e103397, 2020 | 75 | 2020 |
Pannexin‐1 promotes NLRP3 activation during apoptosis but is dispensable for canonical or noncanonical inflammasome activation KW Chen, B Demarco, P Broz European journal of immunology 50 (2), 170-177, 2020 | 71 | 2020 |
Caspase-1 cleaves Bid to release mitochondrial SMAC and drive secondary necrosis in the absence of GSDMD R Heilig, M Dilucca, D Boucher, KW Chen, D Hancz, B Demarco, ... Life science alliance 3 (6), 2020 | 68 | 2020 |
Cross talk between intracellular pathogens and cell death B Demarco, KW Chen, P Broz Immunological reviews 297 (1), 174-193, 2020 | 47 | 2020 |
Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection E Bjanes, RG Sillas, R Matsuda, B Demarco, T Fettrelet, AA DeLaney, ... PLoS Pathogens 17 (10), e1009967, 2021 | 29 | 2021 |
TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation FA Fischer, LFM Mies, S Nizami, E Pantazi, S Danielli, B Demarco, ... Proceedings of the National Academy of Sciences 118 (38), e2009309118, 2021 | 25 | 2021 |
Comparative analysis of the coordinated motion of Hsp70s from different organelles observed by single-molecule three-color FRET L Voith von Voithenberg, A Barth, V Trauschke, B Demarco, S Tyagi, ... Proceedings of the National Academy of Sciences 118 (33), e2025578118, 2021 | 15 | 2021 |
How pyroptosis contributes to inflammation and fibroblast-macrophage cross-talk in rheumatoid arthritis B Demarco, S Danielli, FA Fischer, JS Bezbradica Cells 11 (8), 1307, 2022 | 10 | 2022 |
Pannexin-1 channels bridge apoptosis to NLRP3 inflammasome activation B Demarco, KW Chen, P Broz Molecular & cellular oncology 6 (4), 1610324, 2019 | 6 | 2019 |
The ion channel CALHM6 controls bacterial infection‐induced cellular cross‐talk at the immunological synapse S Danielli, Z Ma, E Pantazi, A Kumar, B Demarco, FA Fischer, U Paudel, ... The EMBO Journal 42 (7), e111450, 2023 | 5 | 2023 |
Detection of gasdermin activation and lytic cell death during pyroptosis and apoptosis B Demarco, S Ramos, P Broz Effector-Triggered Immunity: Methods and Protocols, 209-237, 2022 | 4 | 2022 |
Gasdermin D is the only Gasdermin that provides non-redundant protection against acute Salmonella gut infection SA Fattinger, L Maurer, P Geiser, U Enz, S Ganguillet, E Gül, S Kroon, ... bioRxiv, 2022.11. 24.517575, 2022 | 3 | 2022 |
Gasdermin D is the only Gasdermin that provides protection against acute Salmonella gut infection in mice SA Fattinger, L Maurer, P Geiser, EM Bernard, U Enz, S Ganguillet, E Gül, ... Proceedings of the National Academy of Sciences 120 (48), e2315503120, 2023 | 2 | 2023 |
The Card19 locus of murine chromosome 13 regulates terminal cell lysis downstream of caspase activation and Gasdermin-D cleavage Card19 locus regulates caspase-dependent cell lysis E Bjanes, RG Sillas, R Matsuda, B Demarco, T Fettrelet, AA Delaney, ... bioRxiv, 2021 | 2 | 2021 |