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Donald Newmeyer
Donald Newmeyer
La Jolla Institute for Allergy and Immunology
Verified email at lji.org
Title
Cited by
Cited by
Year
The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis
RM Kluck, E Bossy-Wetzel, DR Green, DD Newmeyer
Science 275 (5303), 1132-1136, 1997
61431997
Ordering the cytochrome c–initiated caspase cascade: hierarchical activation of caspases-2,-3,-6,-7,-8, and-10 in a caspase-9–dependent manner
EA Slee, MT Harte, RM Kluck, BB Wolf, CA Casiano, DD Newmeyer, ...
The Journal of cell biology 144 (2), 281-292, 1999
25641999
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
JE Chipuk, T Kuwana, L Bouchier-Hayes, NM Droin, DD Newmeyer, ...
Science 303 (5660), 1010-1014, 2004
25172004
Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane
T Kuwana, MR Mackey, G Perkins, MH Ellisman, M Latterich, R Schneiter, ...
Cell 111 (3), 331-342, 2002
18962002
Mitochondria: releasing power for life and unleashing the machineries of death
DD Newmeyer, S Ferguson-Miller
Cell 112 (4), 481-490, 2003
16642003
BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly
T Kuwana, L Bouchier-Hayes, JE Chipuk, C Bonzon, BA Sullivan, ...
Molecular cell 17 (4), 525-535, 2005
15472005
Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD‐specific caspase activation and independently of mitochondrial transmembrane depolarization
E Bossy‐Wetzel, DD Newmeyer, DR Green
The EMBO journal, 1998
15281998
Bcl-2-family proteins and the role of mitochondria in apoptosis
T Kuwana, DD Newmeyer
Current opinion in cell biology 15 (6), 691-699, 2003
8342003
Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria
DD Newmeyer, DM Farschon, JC Reed
Cell 79 (2), 353-364, 1994
7811994
PUMA couples the nuclear and cytoplasmic proapoptotic function of p53
JE Chipuk, L Bouchier-Hayes, T Kuwana, DD Newmeyer, DR Green
Science 309 (5741), 1732-1735, 2005
7212005
Nuclear import can be separated into distinct steps in vitro: nuclear pore binding and translocation
DD Newmeyer, DJ Forbes
Cell 52 (5), 641-653, 1988
6541988
Inhibition of in vitro nuclear transport by a lectin that binds to nuclear pores.
DR Finlay, DD Newmeyer, TM Price, DJ Forbes
The Journal of cell biology 104 (2), 189-200, 1987
6131987
GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation
A Colell, JE Ricci, S Tait, S Milasta, U Maurer, L Bouchier-Hayes, ...
Cell 129 (5), 983-997, 2007
5942007
Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process
NJ Waterhouse, JC Goldstein, O Von Ahsen, M Schuler, DD Newmeyer, ...
The Journal of cell biology 153 (2), 319-328, 2001
5122001
Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c
T Kuwana, JJ Smith, M Muzio, V Dixit, DD Newmeyer, S Kornbluth
Journal of Biological Chemistry 273 (26), 16589-16594, 1998
4971998
Cytochrome c activation of CPP32‐like proteolysis plays a critical role in a Xenopus cell‐free apoptosis system
RM Kluck, SJ Martin, BM Hoffman, JS Zhou, DR Green, DD Newmeyer
The EMBO journal, 1997
4891997
The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol
RM Kluck, MD Esposti, G Perkins, C Renken, T Kuwana, E Bossy-Wetzel, ...
The Journal of cell biology 147 (4), 809-822, 1999
4091999
Preservation of Mitochondrial Structure and Function after Bid- or Bax-Mediated Cytochrome c Release
O von Ahsen, C Renken, G Perkins, RM Kluck, E Bossy-Wetzel, ...
The Journal of cell biology 150 (5), 1027-1036, 2000
3332000
Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization
R Yamaguchi, L Lartigue, G Perkins, RT Scott, A Dixit, Y Kushnareva, ...
Molecular cell 31 (4), 557-569, 2008
3182008
Mitochondria: pharmacological manipulation of cell death
L Bouchier-Hayes, L Lartigue, DD Newmeyer
The Journal of clinical investigation 115 (10), 2640-2647, 2005
3112005
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