| CD8 T cells utilize TRAIL to control influenza virus infection EL Brincks, A Katewa, TA Kucaba, TS Griffith, KL Legge The Journal of Immunology 181 (7), 4918-4925, 2008 | 272 | 2008 |
| Cellular inhibitor of apoptosis protein cIAP2 protects against pulmonary tissue necrosis during influenza virus infection to promote host survival IG Rodrigue-Gervais, K Labbé, M Dagenais, J Dupaul-Chicoine, ... Cell host & microbe 15 (1), 23-35, 2014 | 178 | 2014 |
| Antigen-specific memory regulatory CD4+ Foxp3+ T cells control memory responses to influenza virus infection EL Brincks, AD Roberts, T Cookenham, S Sell, JE Kohlmeier, ... The Journal of Immunology 190 (7), 3438-3446, 2013 | 176 | 2013 |
| Inflammatory chemokine receptors regulate CD8+ T cell contraction and memory generation following infection JE Kohlmeier, WW Reiley, G Perona-Wright, ML Freeman, EJ Yager, ... Journal of Experimental Medicine 208 (8), 1621-1634, 2011 | 174 | 2011 |
| TNF-related apoptosis-inducing ligand (TRAIL) exerts therapeutic efficacy for the treatment of pneumococcal pneumonia in mice K Steinwede, S Henken, J Bohling, R Maus, B Ueberberg, C Brumshagen, ... Journal of Experimental Medicine 209 (11), 1937-1952, 2012 | 108 | 2012 |
| TRAIL gene therapy: from preclinical development to clinical application TS Griffith, B Stokes, TA Kucaba, JK Earel Jr, RL VanOosten, EL Brincks, ... Current gene therapy 9 (1), 9-19, 2009 | 108 | 2009 |
| Alterations in antigen-specific naive CD4 T cell precursors after sepsis impairs their responsiveness to pathogen challenge J Cabrera-Perez, SA Condotta, BR James, SW Kashem, EL Brincks, ... The Journal of Immunology 194 (4), 1609-1620, 2015 | 70 | 2015 |
| Cutting edge: elevated leptin during diet-induced obesity reduces the efficacy of tumor immunotherapy KA Murphy, BR James, FV Sjaastad, TA Kucaba, H Kim, EL Brincks, ... The Journal of Immunology 201 (7), 1837-1841, 2018 | 51 | 2018 |
| Phase II trial of the IDO pathway inhibitor indoximod plus pembrolizumab for the treatment of patients with advanced melanoma Y Zakharia, RR McWilliams, O Rixe, J Drabick, MF Shaheen, ... Journal for immunotherapy of cancer 9 (6), 2021 | 50 | 2021 |
| PMN and anti-tumor immunity—the case of bladder cancer immunotherapy EL Brincks, MC Risk, TS Griffith Seminars in cancer biology 23 (3), 183-189, 2013 | 50 | 2013 |
| The magnitude of the T cell response to a clinically significant dose of influenza virus is regulated by TRAIL EL Brincks, P Gurung, RA Langlois, EA Hemann, KL Legge, TS Griffith The Journal of Immunology 187 (9), 4581-4588, 2011 | 48 | 2011 |
| Influenza-induced expression of functional tumor necrosis factor-related apoptosis-inducing ligand on human peripheral blood mononuclear cells EL Brincks, TA Kucaba, KL Legge, TS Griffith Human immunology 69 (10), 634-646, 2008 | 46 | 2008 |
| CpG-mediated modulation of MDSC contributes to the efficacy of Ad5-TRAIL therapy against renal cell carcinoma BR James, KG Anderson, EL Brincks, TA Kucaba, LA Norian, D Masopust, ... Cancer Immunology, Immunotherapy 63, 1213-1227, 2014 | 39 | 2014 |
| Novel roles for IL-15 in T cell survival EL Brincks, DL Woodland F1000 biology reports 2, 2010 | 35 | 2010 |
| Improved anti-tumor immunity and efficacy upon combination of the IDO1 inhibitor GDC-0919 with anti-PD-l1 blockade versus anti-PD-l1 alone in preclinical tumor models J Spahn, J Peng, E Lorenzana, D Kan, T Hunsaker, E Segal, M Mautino, ... Journal for immunotherapy of cancer 3, 1-1, 2015 | 34 | 2015 |
| Discovery of indoximod prodrugs and characterization of clinical candidate NLG802 S Kumar, FA Jaipuri, JP Waldo, H Potturi, A Marcinowicz, J Adams, ... European Journal of Medicinal Chemistry 198, 112373, 2020 | 29 | 2020 |
| Indoximod opposes the immunosuppressive effects mediated by IDO and TDO via modulation of AhR function and activation of mTORC1 EL Brincks, J Adams, L Wang, B Turner, A Marcinowicz, J Ke, M Essmann, ... Oncotarget 11 (25), 2438, 2020 | 26 | 2020 |
| Effective TRAIL-based immunotherapy requires both plasmacytoid and CD8α dendritic cells BR James, EL Brincks, TA Kucaba, L Boon, TS Griffith Cancer Immunology, Immunotherapy 63, 685-697, 2014 | 26 | 2014 |
| Systemic immunological tolerance to ocular antigens is mediated by TRAIL-expressing CD8+ T cells TS Griffith, EL Brincks, P Gurung, TA Kucaba, TA Ferguson The Journal of Immunology 186 (2), 791-798, 2011 | 26 | 2011 |
| A novel prodrug of indoximod with enhanced pharmacokinetic properties MR Mautino, S Kumar, H Zhuang, J Waldo, F Jaipuri, H Potturi, E Brincks, ... Cancer Research 77 (13_Supplement), 4076-4076, 2017 | 18 | 2017 |
