| SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals NC Gassen, J Papies, T Bajaj, J Emanuel, F Dethloff, RL Chua, J Trimpert, ... Nature communications 12 (1), 3818, 2021 | 203 | 2021 |
| Analysis of SARS-CoV-2-controlled autophagy reveals spermidine, MK-2206, and niclosamide as putative antiviral therapeutics NC Gassen, J Papies, T Bajaj, F Dethloff, J Emanuel, K Weckmann, ... BioRxiv, 2020.04. 15.997254, 2020 | 154 | 2020 |
| Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion S Martinelli, EA Anderzhanova, T Bajaj, S Wiechmann, F Dethloff, ... Nature Communications 12 (1), 4643, 2021 | 65 | 2021 |
| The co-chaperone Fkbp5 shapes the acute stress response in the paraventricular nucleus of the hypothalamus of male mice AS Häusl, LM Brix, J Hartmann, ML Pöhlmann, JP Lopez, D Menegaz, ... Molecular Psychiatry 26 (7), 3060-3076, 2021 | 58 | 2021 |
| Mineralocorticoid receptors dampen glucocorticoid receptor sensitivity to stress via regulation of FKBP5 J Hartmann, T Bajaj, C Klengel, C Chatzinakos, T Ebert, N Dedic, ... Cell reports 35 (9), 2021 | 53 | 2021 |
| Macrocyclic FKBP51 ligands define a transient binding mode with enhanced selectivity AM Voll, C Meyners, MC Taubert, T Bajaj, T Heymann, S Merz, ... Angewandte Chemie International Edition 60 (24), 13257-13263, 2021 | 23 | 2021 |
| Chemical phosphoproteomics sheds new light on the targets and modes of action of AKT inhibitors S Wiechmann, B Ruprecht, T Siekmann, R Zheng, M Frejno, E Kunold, ... ACS Chemical Biology 16 (4), 631-641, 2021 | 19 | 2021 |
| Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolism AS Häusl, T Bajaj, LM Brix, ML Pöhlmann, K Hafner, M De Angelis, ... Science advances 8 (10), eabi4797, 2022 | 11 | 2022 |
| Tricyclic antidepressants target FKBP51 SUMOylation to restore glucocorticoid receptor activity ML Budziñski, C Sokn, R Gobbini, B Ugo, M Antunica-Noguerol, S Senin, ... Molecular Psychiatry 27 (5), 2533-2545, 2022 | 9 | 2022 |
| Single-nucleus transcriptome profiling of dorsolateral prefrontal cortex: mechanistic roles for neuronal gene expression, including the 17q21. 31 locus, in PTSD stress response C Chatzinakos, CD Pernia, FG Morrison, A Iatrou, KM McCullough, ... American Journal of Psychiatry 180 (10), 739-754, 2023 | 8 | 2023 |
| SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals. Nat Commun 12: 3818 NC Gassen, J Papies, T Bajaj, J Emanuel, F Dethloff, RL Chua, J Trimpert, ... | 8 | 2021 |
| Myo-inositol levels in the dorsal hippocampus serve as glial prognostic marker of mild cognitive impairment in mice T Ebert, DE Heinz, S Almeida-Corrêa, R Cruz, F Dethloff, T Stark, T Bajaj, ... Frontiers in aging neuroscience 13, 731603, 2021 | 7 | 2021 |
| Analysis of SARS-CoV-2-Controlled Autophagy Reveals Spermidine, MK-2206, and Niclosamide as Putative Antiviral Therapeutics. bioRxiv 2020, 2020.04. 15.997254, doi: 10.1101/2020 … NC Gassen, J Papies, T Bajaj, F Dethloff, J Emanuel, K Weckmann, ... Supplemental Data File for Jara et al, Inhaled Niclosamide in Rats and Hamsters, 0 | 7 | |
| Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning J Stepan, DE Heinz, F Dethloff, T Bajaj, A Zellner, K Hafner, S Wiechmann, ... Cell Reports 41 (10), 2022 | 6 | 2022 |
| FKBP5/FKBP51 on weight watch: central FKBP5 links regulatory WIPI protein networks to autophagy and metabolic control T Bajaj, AS Häusl, MV Schmidt, NC Gassen Autophagy 18 (11), 2756-2758, 2022 | 6 | 2022 |
| A rare heterozygous TREM2 coding variant identified in familial clustering of dementia affects an intrinsically disordered protein region and function of TREM2 M Karsak, K Glebov, M Scheffold, T Bajaj, A Kawalia, I Karaca, S Rading, ... Human mutation 41 (1), 169-181, 2020 | 6 | 2020 |
| Genetik der Alzheimer-Krankheit T Bajaj, A Ramirez, H Wagner-Thelen Medizinische Genetik 30 (2), 259-266, 2018 | 5 | 2018 |
| Loss of function of FIP200 in human pluripotent stem cell-derived neurons leads to axonal pathology and hyperactivity J Wen, A Zellner, NC Braun, T Bajaj, NC Gassen, M Peitz, O Brüstle Translational Psychiatry 13 (1), 143, 2023 | 1 | 2023 |
| Stress-primed secretory autophagy drives extracellular BDNF maturation S Martinelli, EA Anderzhanova, S Wiechmann, F Dethloff, K Weckmann, ... bioRxiv, 2020.05. 13.090514, 2020 | 1 | 2020 |
| Inhibiting Hippo pathway kinases releases WWC1 to promote AMPAR-dependent synaptic plasticity and long-term memory in mice J Stepan, DE Heinz, F Dethloff, S Wiechmann, S Martinelli, K Hafner, ... Science signaling 17 (834), eadj6603, 2024 | | 2024 |
Nils C. GassenResearch Group Leader Bonn University ClinicVerified email at ukbonn.de
