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Roderick A Williams
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Endosome sorting and autophagy are essential for differentiation and virulence of Leishmania major
S Besteiro, RAM Williams, LS Morrison, GH Coombs, JC Mottram
Journal of Biological Chemistry 281 (16), 11384-11396, 2006
2582006
Protein turnover and differentiation in Leishmania
S Besteiro, RAM Williams, GH Coombs, JC Mottram
International journal for parasitology 37 (10), 1063-1075, 2007
2372007
Cysteine peptidases CPA and CPB are vital for autophagy and differentiation in Leishmania mexicana
RA Williams, L Tetley, JC Mottram, GH Coombs
Molecular microbiology 61 (3), 655-674, 2006
1822006
Rapid sequestration of Leishmania mexicana by neutrophils contributes to the development of chronic lesion
BP Hurrell, S Schuster, E Grün, M Coutaz, RA Williams, W Held, ...
PLoS pathogens 11 (5), e1004929, 2015
1222015
Characterization of unusual families of ATG8-like proteins and ATG12 in the protozoan parasite Leishmania major
RAM Williams, KL Woods, L Juliano, JC Mottram, GH Coombs
Autophagy 5 (2), 159-172, 2009
1052009
3-Mercaptopyruvate Sulfurtransferase of LeishmaniaContains an Unusual C-terminal Extension and Is Involved in Thioredoxin and Antioxidant Metabolism
RAM Williams, SM Kelly, JC Mottram, GH Coombs
Journal of Biological Chemistry 278 (3), 1480-1486, 2003
982003
ATG5 is essential for ATG8-dependent autophagy and mitochondrial homeostasis in Leishmania major
RAM Williams, TK Smith, B Cull, JC Mottram, GH Coombs
PLoS pathogens 8 (5), e1002695, 2012
972012
Plasmodium falciparum ATG8 implicated in both autophagy and apicoplast formation
AM Tomlins, F Ben-Rached, RAM Williams, WR Proto, I Coppens, U Ruch, ...
Autophagy 9 (10), 1540-1552, 2013
832013
Two pathways for cysteine biosynthesis in Leishmania major
RAM Williams, GD Westrop, GH Coombs
Biochemical Journal 420 (3), 451-462, 2009
802009
The efficacy of aerosol treatment with non-ionic surfactant vesicles containing amphotericin B in rodent models of leishmaniasis and pulmonary aspergillosis infection
M Alsaadi, JL Italia, AB Mullen, MNVR Kumar, AA Candlish, ...
Journal of controlled release 160 (3), 685-691, 2012
652012
Metabolomic analyses of Leishmania reveal multiple species differences and large differences in amino acid metabolism
GD Westrop, RAM Williams, L Wang, T Zhang, DG Watson, AM Silva, ...
PLoS One 10 (9), e0136891, 2015
552015
Biochemical and immunological characterization of Toxoplasma gondii macrophage migration inhibitory factor
C Sommerville, JM Richardson, RAM Williams, JC Mottram, CW Roberts, ...
Journal of Biological Chemistry 288 (18), 12733-12741, 2013
522013
The Crystal Structure of Leishmania major 3-Mercaptopyruvate Sulfurtransferase A THREE-DOMAIN ARCHITECTURE WITH A SERINE PROTEASE-LIKE TRIAD AT THE ACTIVE SITE
MS Alphey, RAM Williams, JC Mottram, GH Coombs, WN Hunter
Journal of Biological Chemistry 278 (48), 48219-48227, 2003
512003
Glycosome turnover in Leishmania major is mediated by autophagy
B Cull, JL Prado Godinho, JC Fernandes Rodrigues, B Frank, U Schurigt, ...
Autophagy 10 (12), 2143-2157, 2014
492014
Effects of albendazole on growth of primary schoolchildren and the prevalence and intensity of soil-transmitted helminths in Sierra Leone
MM Koroma, RAM Williams, RDB LaHave
J Trop Pediat 42, 371-372, 1996
421996
Distinct roles in autophagy and importance in infectivity of the two ATG4 cysteine peptidases of Leishmania major
RAM Williams, JC Mottram, GH Coombs
Journal of Biological Chemistry 288 (5), 3678-3690, 2013
362013
Registered infant and under-five deaths in Freetown, Sierra Leone from 1987-1991 and a comparison with 1969-1979.
M Hodges, RA Williams
West African journal of medicine 17 (2), 95-98, 1998
161998
Comparison of albendazole and levamisole chemotherapy on prevalence and intensity of common soil-transmitted helminth infections in school children, Sierra Leone.
RA Williams, MM Koroma, M Hodges
West African journal of medicine 16 (3), 179-183, 1997
141997
Co-selection of antibiotic resistance in Gram-negative bacteria caused by pollution legacy in the Clyde estuary
RL Tonner, T Peshkur, R Williams, I McLellan, A Hursthouse, F Henriquez, ...
Strathwide 2018, 2018
2018
Peptidases in Autophagy are Therapeutic Targets for Leishmaniasis
RAM Williams
Trypanosomatid Diseases: Molecular Routes to Drug Discovery, 351-364, 2013
2013
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