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Jugal Dhandhukia, Ph.D.
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Elastin-like polypeptides: Therapeutic applications for an emerging class of nanomedicines
J Despanie, JP Dhandhukia, SF Hamm-Alvarez, JA MacKay
Journal of Controlled Release 240, 93-108, 2016
1492016
A rapamycin-binding protein polymer nanoparticle shows potent therapeutic activity in suppressing autoimmune dacryoadenitis in a mouse model of Sjögren's syndrome
M Shah, MC Edman, SR Janga, P Shi, J Dhandhukia, S Liu, SG Louie, ...
Journal of controlled release 171 (3), 269-279, 2013
1152013
Elastin-based protein polymer nanoparticles carrying drug at both corona and core suppress tumor growth in vivo
P Shi, S Aluri, YA Lin, M Shah, M Edman, J Dhandhukia, H Cui, ...
Journal of controlled release 171 (3), 330-338, 2013
1152013
Switchable elastin-like polypeptides that respond to chemical inducers of dimerization
J Dhandhukia, I Weitzhandler, W Wang, JA MacKay
Biomacromolecules 14 (4), 976-985, 2013
352013
Bifunctional elastin-like polypeptide nanoparticles bind rapamycin and integrins and suppress tumor growth in vivo
JP Dhandhukia, P Shi, S Peddi, Z Li, S Aluri, Y Ju, D Brill, W Wang, ...
Bioconjugate chemistry 28 (11), 2715-2728, 2017
342017
Berunda polypeptides: multi-headed fusion proteins promote subcutaneous administration of rapamycin to breast cancer in vivo
JP Dhandhukia, Z Li, S Peddi, S Kakan, A Mehta, D Tyrpak, J Despanie, ...
Theranostics 7 (16), 3856, 2017
172017
Elastin‐like polypeptide switches: A design strategy to detect multimeric proteins
JP Dhandhukia, DA Brill, A Kouhi, MK Pastuszka, JA MacKay
Protein Science 26 (9), 1785-1795, 2017
102017
Human granulocyte-macrophage colony-stimulating factor fused to elastin-like polypeptides assembles biologically-active nanoparticles
M Park, VP Vaikari, JP Dhandhukia, H Alachkar, JA MacKay
Bioconjugate chemistry 31 (5), 1551-1561, 2020
82020
J. Controlled Release
P Shi, S Aluri, YA Lin, M Shah, M Edman-Woolcott, J Dhandhukia, H Cui, ...
DOI, 2016
52016
Methods and small molecule therapeutics comprising fused elps
JA MacKay, SF Hamm-Alvarez, P Shi, JP Dhandhukia, MK Shah
US Patent App. 14/683,033, 2015
52015
Protein polymer fusions for subcutaneous delivery of small molecules
JA MacKay, JP Dhandhukia, S Peddi, SK Roberts
US Patent App. 16/306,825, 2019
22019
Intra-and extra-cellular manipulation of cell signaling using elastin-like polypeptides
Z Li, D Tyrpak, M Park, C Lee, A Kouhi, J Dhandhukia, S Hamm-Alvarez, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017
2017
Multivalent Smart Elastin-Like Polypeptide Therapeutics with Drug Delivery and Biosensing Applications
J Dhandhukia
University of Southern California, 2017
2017
Artificial organelles: Cellular expression and assembly of polypeptide microdomains
J MacKay, Z Li, A Truong, J Dhandhukia, M Pastuszka, P Shi, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 249, 2015
2015
Protein polymer nanoparticles with multivalent avidity for small molecules or cell-surface receptors
JA MacKay, S Aluri, P Shi, SM Janib, J Dhandhukia, J Gustafson, P Hu, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 246, 2013
2013
Environmentally responsive polymers that respond to dimerization of functional protein domains
J Dhandhukia
University of Southern California, 2012
2012
A human granulocyte-macrophage stimulating factor fused to an elastin-like polypeptide is soluble, forms nanoparticles, and has similar potency to the free protein
M Park, J Dhandhukia, S Peddi, JA MacKay
Drug-Specific Protein Polymer Nanoparticles: In Vivo Reduction of Toxicity and Suppression of Tumor Growth
P Shi, S Aluri, Y Lin, H Cui, J Dhandhukia, JA MacKay
Triggered Assembly of Functional Protein Microdomains in the Cytosol
JA MacKay, MK Pastuszka, P Shi, J Dhandhukia
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Articles 1–19