| Comparison of imatinib, nilotinib and silymarin in the treatment of carbon tetrachloride-induced hepatic oxidative stress, injury and fibrosis ME Shaker, KR Zalata, WZ Mehal, GE Shiha, TM Ibrahim Toxicology and applied pharmacology 252 (2), 165-175, 2011 | 93 | 2011 |
| Celastrol ameliorates murine colitis via modulating oxidative stress, inflammatory cytokines and intestinal homeostasis ME Shaker, SA Ashamallah, ME Houssen Chemico-Biological Interactions 210, 26-33, 2014 | 91 | 2014 |
| Nilotinib counteracts thioacetamide‐induced hepatic oxidative stress and attenuates liver fibrosis progression ME Shaker, HA Salem, GE Shiha, TM Ibrahim Fundamental & clinical pharmacology 25 (2), 248-257, 2011 | 67 | 2011 |
| Comparison of vitamin E, L-carnitine and melatonin in ameliorating carbon tetrachloride and diabetes induced hepatic oxidative stress ME Shaker, ME Houssen, EM Abo-Hashem, TM Ibrahim Journal of physiology and biochemistry 65, 225-233, 2009 | 65 | 2009 |
| Nilotinib induces apoptosis and autophagic cell death of activated hepatic stellate cells via inhibition of histone deacetylases ME Shaker, A Ghani, GE Shiha, TM Ibrahim, WZ Mehal Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (8), 1992-2003, 2013 | 62 | 2013 |
| Modulation of carbon tetrachloride-induced hepatic oxidative stress, injury and fibrosis by olmesartan and omega-3 AA Shaaban, ME Shaker, KR Zalata, HA El-Kashef, TM Ibrahim Chemico-biological interactions 207, 81-91, 2014 | 54 | 2014 |
| Comparison of early treatment with low doses of nilotinib, imatinib and a clinically relevant dose of silymarin in thioacetamide-induced liver fibrosis ME Shaker, GE Shiha, TM Ibrahim European journal of pharmacology 670 (2-3), 593-600, 2011 | 49 | 2011 |
| Optimization and SAR investigation of novel 2, 3-dihydropyrazino [1, 2-a] indole-1, 4-dione derivatives as EGFR and BRAFV600E dual inhibitors with potent antiproliferative and … HAM Gomaa, ME Shaker, SI Alzarea, OM Hendawy, FAM Mohamed, ... Bioorganic Chemistry 120, 105616, 2022 | 40 | 2022 |
| The SMAC mimetic BV6 induces cell death and sensitizes different cell lines to TNF-α and TRAIL-induced apoptosis M El-Mesery, ME Shaker, A Elgaml Experimental Biology and Medicine 241 (18), 2015-2022, 2016 | 40 | 2016 |
| Therapeutic opportunities in damage-associated molecular pattern-driven metabolic diseases I Garcia-Martinez, ME Shaker, WZ Mehal Antioxidants & redox signaling 23 (17), 1305-1315, 2015 | 40 | 2015 |
| Clomiphene citrate co-treatment with low dose urinary FSH versus urinary FSH for clomiphene resistant PCOS: randomized controlled trial ME Ghanem, LA Elboghdady, M Hassan, AS Helal, A Gibreel, M Houssen, ... Journal of assisted reproduction and genetics 30, 1477-1485, 2013 | 31 | 2013 |
| The novel TLR9 antagonist COV08-0064 protects from ischemia/reperfusion injury in non-steatotic and steatotic mice livers ME Shaker, BN Trawick, WZ Mehal Biochemical Pharmacology 112, 90-101, 2016 | 28 | 2016 |
| Repression of acetaminophen-induced hepatotoxicity by a combination of celastrol and brilliant blue G HA Abdelaziz, ME Shaker, MF Hamed, NM Gameil Toxicology Letters, 6-18, 2017 | 25 | 2017 |
| Inhibition of the JAK/STAT pathway by ruxolitinib ameliorates thioacetamide-induced hepatotoxicity ME Shaker, SH Hazem, SA Ashamallah Food and Chemical Toxicology 96, 290-301, 2016 | 25 | 2016 |
| The novel Janus kinase inhibitor ruxolitinib confers protection against carbon tetrachloride-induced hepatotoxicity via multiple mechanisms SH Hazem, ME Shaker, SA Ashamallah, TM Ibrahim Chemico-biological interactions 220, 116-127, 2014 | 22 | 2014 |
| Nilotinib interferes with the signalling pathways implicated in acetaminophen hepatotoxicity ME Shaker Basic & clinical pharmacology & toxicology 114 (3), 263-270, 2014 | 21 | 2014 |
| Polymorphisms of glutathione S-transferase π 1 and toll-like receptors 2 and 9: Association with breast cancer susceptibility MF Al‑Harras, ME Houssen, ME Shaker, K Farag, O Farouk, R Monir, ... Oncology letters 11 (3), 2182-2188, 2016 | 20 | 2016 |
| The selective c-Met inhibitor capmatinib offsets cisplatin-nephrotoxicity and doxorubicin-cardiotoxicity and improves their anticancer efficacies ME Shaker, AA Shaaban, MM El-Shafey, ME El-Mesery Toxicology and applied pharmacology 398, 115018, 2020 | 18 | 2020 |
| A new CDK2 inhibitor with 3-hydrazonoindolin-2-one scaffold endowed with anti-breast cancer activity: Design, synthesis, biological evaluation, and in silico insights MM Al-Sanea, AJ Obaidullah, ME Shaker, G Chilingaryan, MM Alanazi, ... Molecules 26 (2), 412, 2021 | 17 | 2021 |
| The anticancer and EGFR-TK/CDK-9 dual inhibitory potentials of new synthetic pyranopyrazole and pyrazolone derivatives: X-ray crystallography, in vitro, and in silico … A Musa, SK Ihmaid, DL Hughes, MA Said, HS Abulkhair, AH El-Ghorab, ... Journal of Biomolecular Structure and Dynamics 41 (21), 12411-12425, 2023 | 16 | 2023 |
Shaaban AAAssociate professor of pharmacology & toxicology, faculty of pharmacy, mansoura universityبريد إلكتروني تم التحقق منه على mans.edu.eg
