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Arvind kumar
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Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs
A Kumar, S Basak, S Rao, Y Gicheru, ML Mayer, MSP Sansom, ...
Nature communications 11 (1), 3752, 2020
932020
High-resolution Structures of multiple 5-HT3AR-setron complexes reveal a novel mechanism of competitive inhibition
S Basak, A Kumar, S Ramsey, E Gibbs, A Kapoor, M Filizola, ...
elife, 2020
352020
AhpC of the mycobacterial antioxidant defense system and its interaction with its reducing partner Thioredoxin-C
CF Wong, J Shin, MS Subramanian Manimekalai, WG Saw, Z Yin, ...
Scientific reports 7 (1), 5159, 2017
282017
Redox chemistry of Mycobacterium tuberculosis alkylhydroperoxide reductase E (AhpE): Structural and mechanistic insight into a mycoredoxin-1 independent reductive …
A Kumar, AM Balakrishna, W Nartey, MSS Manimekalai, G Grüber
Free Radical Biology and Medicine 97, 588-601, 2016
212016
Structural and mechanistic insights into Mycothiol Disulphide Reductase and the Mycoredoxin-1-alkylhydroperoxide reductase E assembly of Mycobacterium tuberculosis
A Kumar, W Nartey, J Shin, MSS Manimekalai, G Grüber
Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (9), 2354-2366, 2017
152017
QSAR studies on diclofenac analogues as potent cyclooxygenase inhibitors using CoMFA and CoMSIA
K Arvind, KA Solomon, SS Rajan
Medicinal Chemistry Research 23, 1789-1796, 2014
112014
Conformational transitions and allosteric modulation in a heteromeric glycine receptor
E Gibbs, E Klemm, D Seiferth, A Kumar, SL Ilca, PC Biggin, S Chakrapani
Nature Communications 14 (1), 1363, 2023
102023
Structural basis for cannabinoid-induced potentiation of alpha1-glycine receptors in lipid nanodiscs
A Kumar, K Kindig, S Rao, AM Zaki, S Basak, MSP Sansom, PC Biggin, ...
Nature Communications 13 (1), 4862, 2022
102022
Substrate‐induced structural alterations of Mycobacterial mycothione reductase and critical residues involved
A Kumar, MS Subramanian Manimekalai, G Grüber
FEBS letters 592 (4), 568-585, 2018
72018
Mechanisms of Activation and Desensitization of Full-length Glycine Receptor in Membranes
A Kumar, S Basak, S Rao, YW Gicheru, M Mayer, MS Sansom, ...
Biophysical Journal 118 (3), 191a, 2020
62020
Structural systems biology approach delineate the functional implications of SNPs in exon junction complex interaction network
DD VM, V Sivaramakrishnan, K Arvind Kumar
Journal of Biomolecular Structure and Dynamics, 1-18, 2023
52023
Recombinant expression and purification of pentameric ligand-gated ion channels for Cryo-EM structural studies
A Kumar, S Basak, S Chakrapani
Methods in Enzymology 652, 81-103, 2021
52021
Elucidate the Binding Mechanism of Various Setrons to 5-HT3AR
S Basak, YW Gicheru, A Kumar, S Chakrapani
Biophysical Journal 118 (3), 190a, 2020
12020
In-silico interaction studies on inhibitory action of Tetranortriterpenoids on Actin
K Arvind, KA Solomon, S Rajan
Int. J. Pharm. Bio. Sci 3 (4), 193-203, 2012
12012
Structure of the human systemic RNAi defective transmembrane protein 1 (hSIDT1) reveals the conformational flexibility of its lipid binding domain
V Navratna, A Kumar, JK Rana, S Mosalaganti
Life Science Alliance 7 (9), 2024
2024
Understanding the molecular basis of mutation-induced dysfunction of lysosomal membrane proteins
V Navratna, A Kumar, S Mosalaganti
Biophysical Journal 123 (3), 210a, 2024
2024
Structure of the human heparan-α-glucosaminide N-acetyltransferase (HGSNAT)
V Navratna, A Kumar, S Mosalaganti
elife, 2024
2024
Structural basis for cannabinoid-induced potentiation of alpha1-glycine receptors in lipid nanodiscs
A Kumar, KJ Kindig, S Rao, AM Zaki, S Basak, MS Sansom, PC Biggin, ...
Biophysical Journal 122 (3), 446a, 2023
2023
Structural characterization of a full-length heteromeric glycine receptor in multiple functional states
E Gibbs, E Krueger, A Kumar, S David, S Ilca, PC Biggin, S Chakrapani
Biophysical Journal 122 (3), 249a, 2023
2023
Identification and characterisation of lipids that are positive allosteric modulators of glycine receptors
CI Gallagher, YC Lin, A Kumar, D Ha, CL Cioffi, S Chakrapani, ML O'Mara, ...
Biophysical Journal 122 (3), 391a, 2023
2023
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