| NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α J Rius, M Guma, C Schachtrup, K Akassoglou, AS Zinkernagel, V Nizet, ... Nature 453 (7196), 807-811, 2008 | 1793 | 2008 |
| Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor T Shimazu, MD Hirschey, J Newman, W He, K Shirakawa, N Le Moan, ... Science 339 (6116), 211-214, 2013 | 1578 | 2013 |
| Fibrinogen as a key regulator of inflammation in disease D Davalos, K Akassoglou Seminars in immunopathology 34, 43-62, 2012 | 1013 | 2012 |
| Resolving postoperative neuroinflammation and cognitive decline N Terrando, LI Eriksson, J Kyu Ryu, T Yang, C Monaco, M Feldmann, ... Annals of neurology 70 (6), 986-995, 2011 | 636 | 2011 |
| Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation D Davalos, J Kyu Ryu, M Merlini, KM Baeten, N Le Moan, MA Petersen, ... Nature communications 3 (1), 1227, 2012 | 566 | 2012 |
| Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha. L Probert, K Akassoglou, M Pasparakis, G Kontogeorgos, G Kollias Proceedings of the National Academy of Sciences 92 (24), 11294-11298, 1995 | 493 | 1995 |
| Chronic optical access through a polished and reinforced thinned skull PJ Drew, AY Shih, JD Driscoll, PM Knutsen, P Blinder, D Davalos, ... Nature methods 7 (12), 981-984, 2010 | 446 | 2010 |
| Extracellular matrix and matrix receptors in blood–brain barrier formation and stroke KM Baeten, K Akassoglou Developmental neurobiology 71 (11), 1018-1039, 2011 | 422 | 2011 |
| Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple … K Akassoglou, J Bauer, G Kassiotis, M Pasparakis, H Lassmann, G Kollias, ... The American journal of pathology 153 (3), 801-813, 1998 | 418 | 1998 |
| Fibrinogen triggers astrocyte scar formation by promoting the availability of active TGF-β after vascular damage C Schachtrup, JK Ryu, MJ Helmrick, E Vagena, DK Galanakis, JL Degen, ... Journal of Neuroscience 30 (17), 5843-5854, 2010 | 415 | 2010 |
| The fibrin-derived γ377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease RA Adams, J Bauer, MJ Flick, SL Sikorski, T Nuriel, H Lassmann, ... The Journal of experimental medicine 204 (3), 571-582, 2007 | 389 | 2007 |
| Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics MA Petersen, JK Ryu, K Akassoglou Nature Reviews Neuroscience 19 (5), 283-301, 2018 | 356 | 2018 |
| Astrocyte-specific but not neuron-specific transmembrane TNF triggers inflammation and degeneration in the central nervous system of transgenic mice. K Akassoglou, L Probert, G Kontogeorgos, G Kollias Journal of Immunology (Baltimore, Md.: 1950) 158 (1), 438-445, 1997 | 324 | 1997 |
| Fibrinogen induces microglia-mediated spine elimination and cognitive impairment in an Alzheimer’s disease model M Merlini, VA Rafalski, PER Coronado, TM Gill, M Ellisman, ... Neuron 101 (6), 1099-1108. e6, 2019 | 291 | 2019 |
| Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism T Xu, KM Stewart, X Wang, K Liu, M Xie, JK Ryu, K Li, T Ma, H Wang, L Ni, ... Nature 548 (7666), 228-233, 2017 | 290 | 2017 |
| Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation JK Ryu, MA Petersen, SG Murray, KM Baeten, A Meyer-Franke, JP Chan, ... Nature communications 6 (1), 8164, 2015 | 261 | 2015 |
| Fibrin inhibits peripheral nerve remyelination by regulating Schwann cell differentiation K Akassoglou, WM Yu, P Akpinar, S Strickland Neuron 33 (6), 861-875, 2002 | 239 | 2002 |
| TNFR1 signalling is critical for the development of demyelination and the limitation of T-cell responses during immune-mediated CNS disease L Probert, HP Eugster, K Akassoglou, J Bauer, K Frei, H Lassmann, ... Brain 123 (10), 2005-2019, 2000 | 230 | 2000 |
| Tissue plasminogen activator–mediated fibrinolysis protects against axonal degeneration and demyelination after sciatic nerve injury K Akassoglou, KW Kombrinck, JL Degen, S Strickland The Journal of cell biology 149 (5), 1157-1166, 2000 | 221 | 2000 |
| Regulation of hepatic stellate cell differentiation by the neurotrophin receptor p75NTR MA Passino, RA Adams, SL Sikorski, K Akassoglou Science 315 (5820), 1853-1856, 2007 | 220 | 2007 |
Dimitrios DavalosAssistant Professor, Neurosciences, Lerner Research Institute, Cleveland ClinicVerified email at ccf.org
