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Igor Cestari
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Trypanosoma cruzi immune evasion mediated by host cell-derived microvesicles
I Cestari, E Ansa-Addo, P Deolindo, JM Inal, MI Ramirez
The Journal of Immunology 188 (4), 1942-1952, 2012
2092012
Genome and Phylogenetic Analyses of Trypanosoma evansi Reveal Extensive Similarity to T. brucei and Multiple Independent Origins for Dyskinetoplasty
J Carnes, A Anupama, O Balmer, A Jackson, M Lewis, R Brown, I Cestari, ...
PLoS neglected tropical diseases 9 (1), e3404, 2015
1532015
Role of early lectin pathway activation in the complement-mediated killing of Trypanosoma cruzi
IS Cestari, A Krarup, RB Sim, JM Inal, MI Ramirez
Molecular immunology 47 (2), 426-437, 2009
1062009
A spectrophotometric assay for quantitative measurement of aminoacyl-tRNA synthetase activity
I Cestari, K Stuart
Journal of biomolecular screening 18 (4), 490-497, 2013
902013
Inefficient complement system clearance of Trypanosoma cruzi metacyclic trypomastigotes enables resistant strains to invade eukaryotic cells
I Cestari, MI Ramirez
PloS one 5 (3), e9721, 2010
832010
The current drug discovery landscape for trypanosomiasis and leishmaniasis: Challenges and strategies to identify drug targets
F Altamura, R Rajesh, CMC Catta‐Preta, NS Moretti, I Cestari
Drug development research 83 (2), 225-252, 2022
732022
Lexis and grammar of mitochondrial RNA processing in trypanosomes
I Aphasizheva, J Alfonzo, J Carnes, I Cestari, J Cruz-Reyes, HU Göringer, ...
Trends in parasitology 36 (4), 337-355, 2020
692020
Human plasma membrane-derived vesicles halt proliferation and induce differentiation of THP-1 acute monocytic leukemia cells
EA Ansa-Addo, S Lange, D Stratton, S Antwi-Baffour, I Cestari, ...
The Journal of Immunology 185 (9), 5236-5246, 2010
662010
Inositol phosphate pathway controls transcription of telomeric expression sites in trypanosomes
I Cestari, K Stuart
Proceedings of the National Academy of Sciences 112 (21), E2803-E2812, 2015
602015
A multiple aminoacyl-tRNA synthetase complex that enhances tRNA-aminoacylation in African trypanosomes
I Cestari, S Kalidas, S Monnerat, A Anupama, MA Phillips, K Stuart
Molecular and cellular biology 33 (24), 4872-4888, 2013
542013
Complement C2 Receptor Inhibitor Trispanning Confers an Increased Ability to Resist Complement-Mediated Lysis in Trypanosoma cruzi
IS Cestari, I Evans-Osses, J Freitas, JM Inal, MI Ramirez
Journal of Infectious Diseases 198 (9), 1276-1283, 2008
542008
Mechanisms of complement lectin pathway activation and resistance by trypanosomatid parasites
I Cestari, I Evans-Osses, LJ Schlapbach, I de Messias-Reason, ...
Molecular immunology 53 (4), 328-334, 2013
522013
Transcriptional regulation of telomeric expression sites and antigenic variation in trypanosomes
I Cestari, K Stuart
Current genomics 19 (2), 119-132, 2018
502018
Comparative proteomic analysis of lysine acetylation in trypanosomes
NS Moretti, I Cestari, A Anupama, K Stuart, S Schenkman
Journal of proteome research 17 (1), 374-385, 2018
462018
GMP synthase is essential for viability and infectivity of Trypanosoma brucei despite a redundant purine salvage pathway
Q Li, C Leija, F Rijo‐Ferreira, J Chen, I Cestari, K Stuart, BP Tu, ...
Molecular microbiology 97 (5), 1006-1020, 2015
372015
Genetic Validation of Aminoacyl-tRNA Synthetases as Drug Targets in Trypanosoma brucei
S Kalidas, I Cestari, S Monnerat, Q Li, S Regmi, N Hasle, M Labaied, ...
Eukaryotic cell 13 (4), 504-516, 2014
362014
Chemogenetic characterization of inositol phosphate metabolic pathway reveals druggable enzymes for targeting kinetoplastid parasites
I Cestari, P Haas, NS Moretti, S Schenkman, K Stuart
Cell chemical biology 23 (5), 608-617, 2016
262016
Iron superoxide dismutases in eukaryotic pathogens: new insights from Apicomplexa and Trypanosoma structures
IQH Phan, DR Davies, NS Moretti, D Shanmugam, I Cestari, A Anupama, ...
Acta Crystallographica Section F: Structural Biology Communications 71 (5 …, 2015
242015
Nuclear phosphatidylinositol 5-phosphatase is essential for allelic exclusion of variant surface glycoprotein genes in trypanosomes
I Cestari, H McLeland-Wieser, K Stuart
Molecular and Cellular Biology 39 (3), e00395-18, 2019
222019
Inhibition of isoleucyl-tRNA synthetase as a potential treatment for Human African Trypanosomiasis
I Cestari, K Stuart
Journal of Biological Chemistry 288 (20), 14256-14263, 2013
222013
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