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Vignesh Kasinath
Vignesh Kasinath
Assistant Professor of Biochemistry, University of Colorado, Boulder
Verified email at colorado.edu - Homepage
Title
Cited by
Cited by
Year
Cryo-EM structures of PRC2 simultaneously engaged with two functionally distinct nucleosomes
S Poepsel, V Kasinath, E Nogales
Nature structural & molecular biology 25 (2), 154-162, 2018
2002018
Structures of human PRC2 with its cofactors AEBP2 and JARID2
V Kasinath, M Faini, S Poepsel, D Reif, A Feng, G Stjepanovic, ...
Science, 2018
1942018
Entropy in molecular recognition by proteins
JA Caro, KW Harpole, V Kasinath, J Lim, J Granja, KG Valentine, ...
Proceedings of the National Academy of Sciences 114 (25), 6563-6568, 2017
1572017
JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications
V Kasinath, C Beck, P Sauer, S Poepsel, J Kosmatka, M Faini, D Toso, ...
Science 371 (6527), eabc3393, 2021
1402021
Microscopic insights into the NMR relaxation-based protein conformational entropy meter
V Kasinath, KA Sharp, AJ Wand
Journal of the American Chemical Society 135 (40), 15092-15100, 2013
1302013
Coupled motion in proteins revealed by pressure perturbation
Y Fu, V Kasinath, VR Moorman, NV Nucci, VJ Hilser, AJ Wand
Journal of the American Chemical Society 134 (20), 8543-8550, 2012
1042012
The I‐tetraplex building block: rational design and controlled fabrication of robust 1D DNA scaffolds through non‐Watson–Crick interactions
HB Ghodke, R Krishnan, K Vignesh, GVP Kumar, C Narayana, Y Krishnan
Angewandte Chemie International Edition 46 (15), 2646-2649, 2007
802007
On the relationship between NMR‐derived amide order parameters and protein backbone entropy changes
KA Sharp, E O'Brien, V Kasinath, AJ Wand
Proteins: Structure, Function, and Bioinformatics 83 (5), 922-930, 2015
672015
A 13C Labeling Strategy Reveals a Range of Aromatic Side Chain Motion in Calmodulin
V Kasinath, KG Valentine, AJ Wand
Journal of the American Chemical Society 135 (26), 9560-9563, 2013
612013
A sharp thermal transition of fast Aromatic‐Ring dynamics in ubiquitin
V Kasinath, Y Fu, KA Sharp, AJ Wand
Angewandte Chemie International Edition 54 (1), 102-107, 2015
322015
Recent structural insights into polycomb repressive complex 2 regulation and substrate binding
V Kasinath, S Poepsel, E Nogales
Biochemistry 58 (5), 346-354, 2018
222018
Banding 2of NMR‐derived methyl order parameters: Implications for protein dynamics
KA Sharp, V Kasinath, AJ Wand
Proteins: Structure, Function, and Bioinformatics 82 (9), 2106-2117, 2014
222014
Structural basis for inactivation of PRC2 by G-quadruplex RNA
J Song, AR Gooding, WO Hemphill, BD Love, A Robertson, L Yao, LI Zon, ...
Science 381 (6664), 1331-1337, 2023
162023
Dynamic and thermodynamic response of the Ras protein Cdc42Hs upon association with the effector domain of PAK3
VR Moorman, KG Valentine, S Bédard, V Kasinath, J Dogan, FM Love, ...
Journal of molecular biology 426 (21), 3520-3538, 2014
122014
DNMT1 inhibition by pUG-fold quadruplex RNA
LI Jansson-Fritzberg, CI Sousa, MJ Smallegan, JJ Song, AR Gooding, ...
RNA 29 (3), 346-360, 2023
112023
JARID2 and AEBP2 regulate PRC2 activity in the presence of H2A ubiquitination or other histone modifications
V Kasinath, C Beck, P Sauer, S Poepsel, J Kosmatka, M Faini, D Toso, ...
BioRxiv, 2020.04. 20.049213, 2020
92020
Structural insights into the interactions of Polycomb Repressive Complex 2 with chromatin
AG Iragavarapu, L Yao, V Kasinath
Biochemical Society Transactions 49 (6), 2639-2653, 2021
42021
Visualization of PRC2-dinucleosome interactions leading to epigenetic repression
S Poepsel, V Kasinath, E Nogales
bioRxiv, 245134, 2018
12018
Structural basis for the inhibition of PRC2 by active transcription histone posttranslational modifications
T Cookis, A Lydecker, PV Sauer, V Kasinath, E Nogales
bioRxiv, 2024.02. 09.579730, 2024
2024
Motion and Conformational Entropy in Protein Function: Creation of an NMR-Based Entropy Meter
V Kasinath, KW Harpole, VR Moorman, KG Valentine, KK Frederick, ...
Biophysical Journal 108 (2), 60a, 2015
2015
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