| Positive selection and compensatory adaptation interact to stabilize non-transmissible plasmids AS Millan, R Peña-Miller, M Toll-Riera, ZV Halbert, AR McLean, ... Nature communications 5 (1), 5208, 2014 | 262 | 2014 |
| When the most potent combination of antibiotics selects for the greatest bacterial load: the smile-frown transition R Pena-Miller, D Laehnemann, G Jansen, A Fuentes-Hernandez, ... PLoS biology 11 (4), e1001540, 2013 | 241 | 2013 |
| Bistable Expression of Virulence Genes in Salmonella Leads to the Formation of an Antibiotic-Tolerant Subpopulation M Arnoldini, IA Vizcarra, R Peña-Miller, N Stocker, M Diard, V Vogel, ... PLoS biology 12 (8), e1001928, 2014 | 209 | 2014 |
| Variability of plasmid fitness effects contributes to plasmid persistence in bacterial communities A Alonso-del Valle, R León-Sampedro, J Rodríguez-Beltrán, ... Nature communications 12 (1), 2653, 2021 | 118* | 2021 |
| Using a sequential regimen to eliminate bacteria at sublethal antibiotic dosages A Fuentes-Hernandez, J Plucain, F Gori, R Pena-Miller, C Reding, ... PLoS biology 13 (4), e1002104, 2015 | 103 | 2015 |
| Multicopy plasmids allow bacteria to escape from fitness trade-offs during evolutionary innovation J Rodriguez-Beltran, JCR Hernandez-Beltran, J DelaFuente, JA Escudero, ... Nature ecology & evolution 2 (5), 873-881, 2018 | 85 | 2018 |
| Antibiotic cycling and antibiotic mixing: which one best mitigates antibiotic resistance? RE Beardmore, R Peña-Miller, F Gori, J Iredell Molecular biology and evolution 34 (4), 802-817, 2017 | 80 | 2017 |
| Genomics of rapid adaptation to antibiotics: convergent evolution and scalable sequence amplification D Laehnemann, R Pena-Miller, P Rosenstiel, R Beardmore, G Jansen, ... Genome biology and evolution 6 (6), 1287-1301, 2014 | 67 | 2014 |
| Genetic dominance governs the evolution and spread of mobile genetic elements in bacteria J Rodríguez-Beltrán, V Sørum, M Toll-Riera, C de la Vega, R Peña-Miller, ... Proceedings of the National Academy of Sciences 117 (27), 15755-15762, 2020 | 57 | 2020 |
| Rotating antibiotics selects optimally against antibiotic resistance, in theory. R Peña-Miller, R Beardmore American Institute of Mathematical Sciences, 2010 | 48 | 2010 |
| Antibiotic cycling versus mixing: The difficulty of using mathematicalmodels to definitively quantify their relative merits RE Beardmore, R Pena-Miller Mathematical Biosciences & Engineering 7 (4), 923-933, 2010 | 43 | 2010 |
| Evaluating the effect of horizontal transmission on the stability of plasmids under different selection regimes R Peña-Miller, R Rodríguez-González, RC MacLean, A San Millan Mobile genetic elements 5 (3), 29-33, 2015 | 28 | 2015 |
| Mathematical models of plasmid population dynamics JCR Hernández-Beltrán, A San Millan, A Fuentes-Hernández, ... Frontiers in Microbiology 12, 3389, 2021 | 26 | 2021 |
| Single-cell time-lapse analysis of depletion of the universally conserved essential protein YgjD T Bergmiller, R Peña-Miller, A Boehm, M Ackermann Bmc Microbiology 11, 1-12, 2011 | 25 | 2011 |
| The optimal deployment of synergistic antibiotics: a control-theoretic approach R Peña-Miller, D Lähnemann, H Schulenburg, M Ackermann, ... Journal of The Royal Society Interface 9 (75), 2488-2502, 2012 | 24 | 2012 |
| Modelling cognitive decline in the Hypertension in the Very Elderly Trial [HYVET] and proposed risk tables for population use R Peters, N Beckett, R Beardmore, R Peña-Miller, K Rockwood, ... PLoS One 5 (7), e11775, 2010 | 22 | 2010 |
| Selecting against antibiotic-resistant pathogens: optimal treatments in the presence of commensal bacteria R Peña-Miller, D Lähnemann, H Schulenburg, M Ackermann, ... Bulletin of mathematical biology 74, 908-934, 2012 | 21 | 2012 |
| Identification of the Flavobacterium johnsoniae cysteate‐fatty acyl transferase required for capnine synthesis and for efficient gliding motility MÁ Vences‐Guzmán, R Peña‐Miller, NA Hidalgo‐Aguilar, ... Environmental microbiology 23 (5), 2448-2460, 2021 | 14 | 2021 |
| Diffusion-driven enhancement of the antibiotic resistance selection window A Fuentes-Hernández, A Hernández-Koutoucheva, AF Muñoz, ... Journal of the Royal Society Interface 16 (158), 20190363, 2019 | 14 | 2019 |
| Testing the optimality properties of a dual antibiotic treatment in a two-locus, two-allele model R Pena-Miller, A Fuentes-Hernandez, C Reding, I Gudelj, R Beardmore Journal of The Royal Society Interface 11 (96), 20131035, 2014 | 14 | 2014 |
Alvaro San MillanSpanish National Centre for Biotechnology - CSICVerified email at cnb.csic.es
