Reduced inflammatory and muscle damage biomarkers following oral supplementation with bioavailable curcumin BK McFarlin, AS Venable, AL Henning, JNB Sampson, K Pennel, ... BBA clinical 5, 72-78, 2016 | 191 | 2016 |
MNK Inhibition Sensitizes KRAS-Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression JRP Knight, C Alexandrou, GL Skalka, N Vlahov, K Pennel, L Officer, ... Cancer discovery 11 (5), 1228-1247, 2021 | 54 | 2021 |
Relationship between immune checkpoint proteins, tumour microenvironment characteristics, and prognosis in primary operable colorectal cancer SSF Al‐Badran, L Grant, MV Campo, J Inthagard, K Pennel, J Quinn, ... The Journal of Pathology: Clinical Research 7 (2), 121-134, 2021 | 22 | 2021 |
The Glasgow Microenvironment Score associates with prognosis and adjuvant chemotherapy response in colorectal cancer PG Alexander, AK Roseweir, KAF Pennel, HC van Wyk, AGMT Powell, ... British journal of cancer 124 (4), 786-796, 2021 | 19 | 2021 |
Signal interaction between the tumour and inflammatory cells in patients with gastrointestinal cancer: Implications for treatment KAF Pennel, JH Park, DC McMillan, AK Roseweir, J Edwards Cellular Signalling 54, 81-90, 2019 | 16 | 2019 |
Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target J Vande Voorde, RT Steven, AK Najumudeen, CA Ford, A Dexter, ... Nature metabolism 5 (8), 1303-1318, 2023 | 10 | 2023 |
Spatially resolved transcriptomics deconvolutes prognostic histological subgroups in patients with colorectal cancer and synchronous liver metastases CS Wood, KAF Pennel, H Leslie, A Legrini, AJ Cameron, ... Cancer Research 83 (8), 1329-1344, 2023 | 7 | 2023 |
The relationship between the Glasgow microenvironment score and markers of epithelial-mesenchymal transition in TNM II-III colorectal cancer PG Alexander, AAM Matly, N Jirapongwattana, KAF Pennel, HC Van Wyk, ... Human Pathology 127, 1-11, 2022 | 6 | 2022 |
MNK Inhibition Sensitizes KRAS-Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression. Cancer Discov 2021; 11 (5): 1228–47 doi 10 … JRP Knight, C Alexandrou, GL Skalka, N Vlahov, K Pennel, L Officer CD-20-0652, 0 | 5 | |
CXCL8 expression is associated with advanced stage, right sidedness, and distinct histological features of colorectal cancer KAF Pennel, JA Quinn, C Nixon, J Inthagard, HC van Wyk, D Chang, ... The Journal of Pathology: Clinical Research 8 (6), 509-520, 2022 | 4 | 2022 |
JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors KAF Pennel, P Hatthakarnkul, CS Wood, GY Lian, SSF Al-Badran, ... Journal of Experimental & Clinical Cancer Research 43 (1), 64, 2024 | 2 | 2024 |
High expression of STAT3 within the tumour‐associated stroma predicts poor outcome in breast cancer patients E Morrow, K Pennel, P Hatthakarnkul, H Leslie, E Mallon, D Andersen, ... Cancer Medicine 12 (12), 13225-13240, 2023 | 2 | 2023 |
Protein expression of S100A2 reveals it association with patient prognosis and immune infiltration profile in colorectal cancer P Hatthakarnkul, A Ammar, KAF Pennel, L Officer-Jones, S Cusumano, ... Journal of Cancer 14 (10), 1837, 2023 | 2 | 2023 |
Spatial expression of IKK-alpha is associated with a differential mutational landscape and survival in primary colorectal cancer M Patel, KAF Pennel, JA Quinn, H Hood, DK Chang, AV Biankin, S Rebus, ... British Journal of Cancer 126 (12), 1704-1714, 2022 | 2 | 2022 |
IKKα as a potential novel target for treatment of colorectal cancer. JA Quinn, M Patel, KAF Pennel, D Flanagan, PG Horgan, DC McMillan, ... Journal of Clinical Oncology 38 (4_suppl), 174-174, 2020 | 2 | 2020 |
The association between tumour sidedness, clinicopathological characteristics and outcomes in patients undergoing curative resection for colon cancer. AM Golder, KAF Pennel, D Mansouri, PG Horgan, CSD Roxburgh, ... Journal of Clinical Oncology 40 (4_suppl), 148-148, 2022 | 1 | 2022 |
Validation of the Glasgow Microenvironment Score in patients with colon cancer: A pathology-based prognostic tool. PG Alexander, AK Roseweir, KAF Pennel, HC Van Wyk, AGMT Powell, ... Journal of Clinical Oncology 38 (4_suppl), 206-206, 2020 | 1 | 2020 |
The Glasgow Microenvironment Score: an exemplar of contemporary biomarker evolution in colorectal cancer K Knight, C Bigley, K Pennel, J Hay, N Maka, D McMillan, J Park, ... Journal of Pathology: Clinical Research, 2024 | | 2024 |
Histopathological tumour microenvironment score independently predicts outcome in primary operable colorectal cancer P Hatthakarnkul, K Pennel, P Alexander, H Van Wyk, A Roseweir, ... The Journal of Pathology: Clinical Research 10 (3), e12374, 2024 | | 2024 |
The relationship between tumour necrosis, systemic inflammation, body composition and survival in patients with colon cancer Does tumour necrosis drive cachexia? RD Dolan, K Pennel, J Thompson, M McKenzie, P Alexander, C Richards, ... | | 2024 |