Directed evolution of polymerase function by compartmentalized self-replication FJ Ghadessy, JL Ong, P Holliger Proceedings of the National Academy of Sciences 98 (8), 4552-4557, 2001 | 594 | 2001 |
Examining sources of error in PCR by single-molecule sequencing V Potapov, JL Ong PloS one 12 (1), e0169774, 2017 | 342 | 2017 |
Comprehensive profiling of four base overhang ligation fidelity by T4 DNA Ligase and application to DNA assembly V Potapov, JL Ong, RB Kucera, BW Langhorst, K Bilotti, JM Pryor, ... ACS synthetic biology 7 (11), 2665-2674, 2018 | 157 | 2018 |
Directed evolution of DNA polymerase, RNA polymerase and reverse transcriptase activity in a single polypeptide JL Ong, D Loakes, S Jaroslawski, K Too, P Holliger Journal of molecular biology 361 (3), 537-550, 2006 | 153 | 2006 |
Compartmentalised self replication method for in vitro evolution of molecular libraries P Holliger, F Ghadassy, JL Ong US Patent 7,514,210, 2009 | 133 | 2009 |
Base modifications affecting RNA polymerase and reverse transcriptase fidelity V Potapov, X Fu, N Dai, IR Corrêa Jr, NA Tanner, JL Ong Nucleic acids research 46 (11), 5753-5763, 2018 | 103 | 2018 |
Methods of increasing the concentration of a nucleic acid P Hollinger, F Ghadassy, JL Ong US Patent App. 12/070,232, 2008 | 86 | 2008 |
Isolation of receptor–ligand pairs by capture of long-lived multivalent interaction complexes RMT de Wildt, IM Tomlinson, JL Ong, P Holliger Proceedings of the National Academy of Sciences 99 (13), 8530-8535, 2002 | 59 | 2002 |
A single-molecule sequencing assay for the comprehensive profiling of T4 DNA ligase fidelity and bias during DNA end-joining V Potapov, JL Ong, BW Langhorst, K Bilotti, D Cahoon, B Canton, ... Nucleic acids research, 2018 | 36 | 2018 |
Mutant reverse transcriptase Y Xu, J Ong, S Guan, N Nichols US Patent 9,580,698, 2017 | 30 | 2017 |
Mutant reverse transcriptase Y Xu, J Ong, S Guan, N Nichols US Patent 9,932,567, 2018 | 26 | 2018 |
Pol V-mediated translesion synthesis elicits localized untargeted mutagenesis during post-replicative gap repair A Isogawa, JL Ong, V Potapov, RP Fuchs, S Fujii Cell reports 24 (5), 1290-1300, 2018 | 19 | 2018 |
Correction: Examining Sources of Error in PCR by Single-Molecule Sequencing V Potapov, JL Ong PloS one 12 (7), e0181128, 2017 | 18 | 2017 |
DNA polymerases J Ong, TC Evans Jr, N Tanner US Patent 9,127,258, 2015 | 13 | 2015 |
Novel DNA Polymerases J Ong, TC Evans Jr, N Tanner US Patent App. 14/619,712, 2015 | 13* | 2015 |
Optimization of Golden Gate assembly through application of ligation sequence-dependent fidelity and bias profiling P Vladimir, JL Ong, RB Kucera, BW Langhorst, K Bilotti, JM Pryor, ... bioRxiv, 322297, 2018 | 11 | 2018 |
DNA polymerases J Ong, TC Evans Jr, N Tanner US Patent 9,157,073, 2015 | 11 | 2015 |
DNA polymerases J Ong, TC Evans Jr, N Tanner US Patent 8,993,298, 2015 | 11 | 2015 |
Polymerase engineering: from PCR and sequencing to synthetic biology VB Pinheiro, JL Ong, P Holliger Protein Engineering Handbook 3, 279-302, 2013 | 8 | 2013 |
Intravesicle isothermal DNA replication D Torino, C Del Bianco, LA Ross, JL Ong, SS Mansy BMC research notes 4 (1), 128, 2011 | 6 | 2011 |