Human Arylamine N-Acetyltransferase Genes: Isolation, Chromosomal Localization, and Functional Expression M Blum, DM Grant, W McBride, M Heim, UA Meyer DNA and cell biology 9 (3), 193-203, 1990 | 575 | 1990 |
Nomenclature for N-acetyltransferases KP Vatsis, WW Weber, DA Bell, JM Dupret, DAP Evans, DM Grant, ... Pharmacogenetics and Genomics 5 (1), 1-17, 1995 | 510 | 1995 |
Molecular mechanism of slow acetylation of drugs and carcinogens in humans. M Blum, A Demierre, DM Grant, M Heim, UA Meyer Proceedings of the National Academy of Sciences 88 (12), 5237-5241, 1991 | 490 | 1991 |
Differences in metabolism of sulfonamides predisposing to idiosyncratic toxicity NH Shear, SP Spielberg, DM Grant, BK Tang, W KALOW Annals of Internal Medicine 105 (2), 179-184, 1986 | 456 | 1986 |
Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases DW Hein, MA Doll, TD Rustan, K Gray, Y Feng, RJ Ferguson, DM Grant Carcinogenesis 14 (8), 1633-1638, 1993 | 428 | 1993 |
Variability in caffeine metabolism DM Grant, BK Tang, W Kalow Clinical Pharmacology & Therapeutics 33 (5), 591-602, 1983 | 350 | 1983 |
Monomorphic and polymorphic human arylamine N-acetyltransferases: a comparison of liver isozymes and expressed products of two cloned genes. DM Grant, M Blum, M Beer, UA Meyer Molecular pharmacology 39 (2), 184-191, 1991 | 337 | 1991 |
Human acetyltransferase polymorphisms DM Grant, NC Hughes, SA Janezic, GH Goodfellow, HJ Chen, A Gaedigk, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 376 (1 …, 1997 | 326 | 1997 |
Biotransformation of caffeine, paraxanthine, theophylline, and theobromine by polycyclic aromatic hydrocarbon-inducible cytochrome (s) P-450 in human liver microsomes. ME Campbell, DM Grant, T Inaba, W Kalow Drug Metabolism and Disposition 15 (2), 237-249, 1987 | 280 | 1987 |
A simple test for acetylator phenotype using caffeine. DM Grant, BK Tang, W Kalow British journal of clinical pharmacology 17 (4), 459-464, 1984 | 259 | 1984 |
Detoxification pathways in the liver DM Grant Journal of inherited metabolic disease 14, 421-430, 1991 | 241 | 1991 |
Three-dimensional culture and cAMP signaling promote the maturation of human pluripotent stem cell-derived hepatocytes S Ogawa, J Surapisitchat, C Virtanen, M Ogawa, M Niapour, KS Sugamori, ... Development 140 (15), 3285-3296, 2013 | 188 | 2013 |
Acetylation pharmacogenetics. The slow acetylator phenotype is caused by decreased or absent arylamine N-acetyltransferase in human liver. DM Grant, K Mörike, M Eichelbaum, UA Meyer The Journal of clinical investigation 85 (3), 968-972, 1990 | 175 | 1990 |
Localization of N-Acetyltransferases NAT1 and NAT2 in Human Tissues KF Windmill, A Gaedigk, P de la M. Hall, H Samaratunga, DM Grant, ... Toxicological Sciences 54 (1), 19-29, 2000 | 172 | 2000 |
Characterization of the microsomal epoxide hydrolase gene in patients with anticonvulsant adverse drug reactions A Gaedigk, SP Spielberg, DM Grant Pharmacogenetics and Genomics 4 (3), 142-153, 1994 | 166 | 1994 |
The role of xenobiotic metabolizing enzymes in arylamine toxicity and carcinogenesis: functional and localization studies KF Windmill, RA McKinnon, X Zhu, A Gaedigk, DM Grant, ME McManus Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 376 (1 …, 1997 | 165 | 1997 |
Site-directed mutagenesis of recombinant human arylamine N-acetyltransferase expressed in Escherichia coli. Evidence for direct involvement of Cys68 in the catalytic mechanism … JM Dupret, DM Grant Journal of Biological Chemistry 267 (11), 7381-7385, 1992 | 157 | 1992 |
Identification and characterization of variant alleles of human acetyltransferase NAT1 with defective function using p-aminosalicylate as an in-vivo and in-vitro probe NC Hughes, SA Janezic, KL McQueen, MAS Jewett, T Castranio, DA Bell, ... Pharmacogenetics and Genomics 8 (1), 55-66, 1998 | 156 | 1998 |
Molecular genetics of the N-acetyltransferases DM Grant Pharmacogenetics and Genomics 3 (1), 45-50, 1993 | 156 | 1993 |
Evaluation of caffeine as a test drug for CYP1A2, NAT2 and CYP2E1 phenotyping in man by in vivo versus in vitro correlations U Fuhr, KL Rost, R Engelhardt, M Sachs, D Liermann, C Belloc, P Beaune, ... Pharmacogenetics and Genomics 6 (2), 159-176, 1996 | 153 | 1996 |