Chemopreventive and anticancer activity of flavonoids and its possibility for clinical use by combining with conventional chemotherapeutic agents H Kikuchi, B Yuan, X Hu, M Okazaki American journal of cancer research 9 (8), 1517, 2019 | 104 | 2019 |
Cytotoxic effects of flavonoids against a human colon cancer derived cell line, COLO 201: a potential natural anti-cancer substance M Imai, H Kikuchi, T Denda, K Ohyama, C Hirobe, H Toyoda Cancer Letters 276 (1), 74-80, 2009 | 91 | 2009 |
Cytotoxicity of Vitex agnus-castus fruit extract and its major component, casticin, correlates with differentiation status in leukemia cell lines H Kikuchi, B Yuan, Y Nishimura, M Imai, R Furutani, S Kamoi, M Seno, ... International Journal of Oncology 43 (6), 1976-1984, 2013 | 45 | 2013 |
Involvement of histone H3 phosphorylation through p38 MAPK pathway activation in casticin-induced cytocidal effects against the human promyelocytic cell line HL-60 H Kikuchi, B Yuan, E Yuhara, N Takagi, H Toyoda International Journal of Oncology 43 (6), 2046-2056, 2013 | 40 | 2013 |
Involvement of histone H3 phosphorylation via the activation of p38 MAPK pathway and intracellular redox status in cytotoxicity of HL-60 cells induced by Vitex agnus-castus … H Kikuchi, B Yuan, E Yuhara, M Imai, R Furutani, S Fukushima, S Hazama, ... International journal of oncology 45 (2), 843-852, 2014 | 33 | 2014 |
Contribution of membrane progesterone receptor α to the induction of progesterone-mediated apoptosis associated with mitochondrial membrane disruption and caspase cascade … A Kon, B Yuan, T Hanazawa, H Kikuchi, M Sato, R Furutani, N Takagi, ... Oncology reports 30 (4), 1965-1970, 2013 | 25 | 2013 |
Rosehip inhibits xanthine oxidase activity and reduces serum urate levels in a mouse model of hyperuricemia H Kikuchi, S Kogure, R Arai, K Saino, A Ohkubo, T Tsuda, K Sunaga Biomedical reports 6 (5), 539-544, 2017 | 22 | 2017 |
Enhanced cytotoxic effects of arsenite in combination with anthocyanidin compound, delphinidin, against a human leukemia cell line, HL-60 Y Yoshino, BO Yuan, S Okusumi, R Aoyama, R Murota, H Kikuchi, ... Chemico-Biological Interactions 294, 9-17, 2018 | 19 | 2018 |
Cytotoxic effects of pyrrolidine dithiocarbamate in small-cell lung cancer cells, alone and in combination with cisplatin S Tahata, B Yuan, H Kikuchi, N Takagi, T Hirano, H Toyoda International Journal of Oncology 45 (4), 1749-1759, 2014 | 19 | 2014 |
Cytocidal effects of polyphenolic compounds, alone or in combination with, anticancer drugs against cancer cells: potential future application of the combinatory therapy B Yuan, M Imai, H Kikuchi, S Fukushima, S Hazama, T Akaike, Y Yoshino, ... Apoptosis and Medicine, 2012 | 19 | 2012 |
Growth inhibition of a human colon carcinoma cell, COLO 201, by a natural product, Vitex agnus-castus fruits extract, in vivo and in vitro M Imai, B Yuan, H Kikuchi, M Saito, K Ohyama, C Hirobe, T Oshima, ... Advances in Biological Chemistry 2 (1), 20-28, 2012 | 17 | 2012 |
JNK and Autophagy Independently Contributed to Cytotoxicity of Arsenite combined With Tetrandrine via Modulating Cell Cycle Progression in Human Breast … B Yu, B Yuan, JZ Li, A Kiyomi, H Kikuchi, H Hayashi, X Hu, M Okazaki, ... Frontiers in Pharmacology 11, 1087, 2020 | 14 | 2020 |
Differentiation induction of human breast cancer cells by arsenite in combination with tetrandrine B Yu, B Yuan, A Kiyomi, H Kikuchi, H Hayashi, X Hu, M Okazaki, ... American Journal of Translational Research 11 (12), 7310, 2019 | 14 | 2019 |
Effects of tomato juice on the pharmacokinetics of CYP3A4-substrate drugs A Ohkubo, T Chida, H Kikuchi, T Tsuda, K Sunaga asian journal of pharmaceutical sciences 12 (5), 464-469, 2017 | 13 | 2017 |
Enhanced growth inhibitory effect of 5-fluorouracil in combination with Vitex agnus-castus fruits extract against a human colon adenocarcinoma cell line, COLO 201 M Imai, H Kikuchi, B Yuan, Y Aihara, A Mizokuchi, K Ohya-Ma, C Hirobe, ... Journal of Chinese Clinical Medicine 6 (4), 14-19, 2011 | 10 | 2011 |
Synthesis of 4, 4-disubstituted 3, 4-dihydropyrimidin-2 (1H)-ones and-thiones, the corresponding products of Biginelli reaction using ketone, and their antiproliferative effect … Y Nishimura, H Kikuchi, T Kubo, R Arai, Y Toguchi, B Yuan, K Sunaga, ... Chemical and Pharmaceutical Bulletin 70 (2), 111-119, 2022 | 6 | 2022 |
Synthesis of 6-unsubstituted 2-oxo, 2-thioxo, and 2-amino-3, 4-dihydropyrimidines and their antiproliferative effect on HL-60 cells Y Nishimura, H Kikuchi, T Kubo, Y Gokurakuji, Y Nakamura, R Arai, ... Tetrahedron letters 61 (28), 151967, 2020 | 6 | 2020 |
Synthesis of novel 6-unsubstituted 2-aminodihydropyrimidines by Sc (OTf) 3-mediated amination and their antiproliferative effect on HL-60 cells Y Nishimura, H Kikuchi, T Kubo, I Nakakita, M Oguni, M Ohta, R Arai, ... Tetrahedron letters 65, 152760, 2021 | 4 | 2021 |
Effects of hot‑water extracts from 26 herbs on α‑glucosidase activity H Kikuchi, N Toyoda, S Ezawa, S Yoshida, Y Hibino, K Sunaga Molecular Medicine Reports 22 (4), 3525-3532, 2020 | 2 | 2020 |
Heat Shock Response in Human Epithelial Colorectal Adenocarcinoma Caco-2 Cells S Inouye, M Ohno, H Kikuchi, R Akagi Journal of Yasuda Women’s University 40, 383-388, 2012 | 2 | 2012 |