Globular amyloid β‐peptide1−42 oligomer − a homogenous and stable neuropathological protein in Alzheimer's disease S Barghorn, V Nimmrich, A Striebinger, C Krantz, P Keller, B Janson, ... Journal of neurochemistry 95 (3), 834-847, 2005 | 797 | 2005 |
Antiviral effects of recombinant tumour necrosis factor in vitro J Mestan, W Digel, S Mittnacht, H Hillen, D Blohm, A Möller, H Jacobsen, ... Nature 323 (6091), 816-819, 1986 | 522 | 1986 |
Structural characterization of a soluble amyloid β-peptide oligomer L Yu, R Edalji, JE Harlan, TF Holzman, AP Lopez, B Labkovsky, H Hillen, ... Biochemistry 48 (9), 1870-1877, 2009 | 453 | 2009 |
Amyloid β oligomers (Aβ1–42 globulomer) suppress spontaneous synaptic activity by inhibition of P/Q-type calcium currents V Nimmrich, C Grimm, A Draguhn, S Barghorn, A Lehmann, ... Journal of Neuroscience 28 (4), 788-797, 2008 | 328 | 2008 |
Molecular characterization of human and bovine endothelin converting enzyme (ECE‐1) M Schmidt, B Kröger, E Jacob, H Seulberger, T Subkowski, R Otter, ... FEBS letters 356 (2-3), 238-243, 1994 | 252 | 1994 |
Obesity is associated with tissue-specific activation of renal angiotensin-converting enzyme in vivo: evidence for a regulatory role of endothelin M Barton, R Carmona, H Morawietz, LV d’Uscio, W Goettsch, H Hillen, ... Hypertension 35 (1), 329-336, 2000 | 179 | 2000 |
Structure and molecular arrangement of proteolipid protein of central nervous system myelin. W Stoffel, H Hillen, H Giersiefen Proceedings of the National Academy of Sciences 81 (16), 5012-5016, 1984 | 162 | 1984 |
Aβ-globulomers are formed independently of the fibril pathway GP Gellermann, H Byrnes, A Striebinger, K Ullrich, R Mueller, H Hillen, ... Neurobiology of disease 30 (2), 212-220, 2008 | 155 | 2008 |
Generation and therapeutic efficacy of highly oligomer-specific β-amyloid antibodies H Hillen, S Barghorn, A Striebinger, B Labkovsky, R Müller, V Nimmrich, ... Journal of Neuroscience 30 (31), 10369-10379, 2010 | 151 | 2010 |
The primary structure of bovine brain myelin lipophilin (proteolipid apoprotein) W Stoffel, H Hillen, W Schröder, R Deutzmann Walter de Gruyter, Berlin/New York 364 (2), 1455-1466, 1983 | 143 | 1983 |
The beta amyloid dysfunction (BAD) hypothesis for Alzheimer’s disease H Hillen Frontiers in Neuroscience 13, 485010, 2019 | 105 | 2019 |
Amyloid β (1-42) oligomers, derivatives thereof and antibodies thereto, methods of preparation thereof and use thereof H Hillen, A Striebinger US Patent 7,902,328, 2011 | 78 | 2011 |
Two‐dimensional analysis of myocardial protein expression following myocardial ischemia and reperfusion in rabbits H Schwertz, T Längin, H Platsch, J Richert, S Bomm, M Schmidt, H Hillen, ... Proteomics 2 (8), 988-995, 2002 | 77 | 2002 |
Monomeric structures of the zymogen and active catalytic domain of complement protease c1r: further insights into the c1 activation mechanism M Budayova-Spano, W Grabarse, NM Thielens, H Hillen, M Lacroix, ... Structure 10 (11), 1509-1519, 2002 | 69 | 2002 |
Anti-Aβ globulomer 5F7 antibodies S Barghorn, H Hillen, B Labkovsky, AR Striebinger, P Keller, U Ebert US Patent 8,691,224, 2014 | 61 | 2014 |
Humanized antibodies to ab (20-42) globulomer and uses thereof S Barghorn, U Ebert, H Hillen, P Keller, AR Striebinger, B Labkovsky, ... US Patent App. 12/129,469, 2009 | 59 | 2009 |
Screening Method, Process for Purifying of Non-Diffusible A-Beta Oligomers, Selective Antibodies Against Said Non-Diffusible a-Beta Oligomers and a Process for Manufacturing of … H Hillen, A Striebinger, P Keller, S Barghorn, U Ebert US Patent App. 11/885,362, 2009 | 59 | 2009 |
Humanized Antibodies Which Bind To AB (1-42) Globulomer And Uses Thereof H Hillen, S Barghorn, U Ebert, AR Striebinger, P Keller, B Labkovsky, ... US Patent App. 12/129,395, 2009 | 53 | 2009 |
Pharmaceutical proteins D Blohm, C Bollschweiler, H Hillen Angewandte Chemie International Edition in English 27 (2), 207-225, 1988 | 50 | 1988 |
Immunotherapy alleviates amyloid-associated synaptic pathology in an Alzheimer’s disease mouse model MM Dorostkar, S Burgold, S Filser, S Barghorn, B Schmidt, UR Anumala, ... Brain 137 (12), 3319-3326, 2014 | 48 | 2014 |