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Heinz Hillen
Heinz Hillen
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Globular amyloid β‐peptide1−42 oligomer − a homogenous and stable neuropathological protein in Alzheimer's disease
S Barghorn, V Nimmrich, A Striebinger, C Krantz, P Keller, B Janson, ...
Journal of neurochemistry 95 (3), 834-847, 2005
7972005
Antiviral effects of recombinant tumour necrosis factor in vitro
J Mestan, W Digel, S Mittnacht, H Hillen, D Blohm, A Möller, H Jacobsen, ...
Nature 323 (6091), 816-819, 1986
5221986
Structural characterization of a soluble amyloid β-peptide oligomer
L Yu, R Edalji, JE Harlan, TF Holzman, AP Lopez, B Labkovsky, H Hillen, ...
Biochemistry 48 (9), 1870-1877, 2009
4532009
Amyloid β oligomers (Aβ1–42 globulomer) suppress spontaneous synaptic activity by inhibition of P/Q-type calcium currents
V Nimmrich, C Grimm, A Draguhn, S Barghorn, A Lehmann, ...
Journal of Neuroscience 28 (4), 788-797, 2008
3282008
Molecular characterization of human and bovine endothelin converting enzyme (ECE‐1)
M Schmidt, B Kröger, E Jacob, H Seulberger, T Subkowski, R Otter, ...
FEBS letters 356 (2-3), 238-243, 1994
2521994
Obesity is associated with tissue-specific activation of renal angiotensin-converting enzyme in vivo: evidence for a regulatory role of endothelin
M Barton, R Carmona, H Morawietz, LV d’Uscio, W Goettsch, H Hillen, ...
Hypertension 35 (1), 329-336, 2000
1792000
Structure and molecular arrangement of proteolipid protein of central nervous system myelin.
W Stoffel, H Hillen, H Giersiefen
Proceedings of the National Academy of Sciences 81 (16), 5012-5016, 1984
1621984
Aβ-globulomers are formed independently of the fibril pathway
GP Gellermann, H Byrnes, A Striebinger, K Ullrich, R Mueller, H Hillen, ...
Neurobiology of disease 30 (2), 212-220, 2008
1552008
Generation and therapeutic efficacy of highly oligomer-specific β-amyloid antibodies
H Hillen, S Barghorn, A Striebinger, B Labkovsky, R Müller, V Nimmrich, ...
Journal of Neuroscience 30 (31), 10369-10379, 2010
1512010
The primary structure of bovine brain myelin lipophilin (proteolipid apoprotein)
W Stoffel, H Hillen, W Schröder, R Deutzmann
Walter de Gruyter, Berlin/New York 364 (2), 1455-1466, 1983
1431983
The beta amyloid dysfunction (BAD) hypothesis for Alzheimer’s disease
H Hillen
Frontiers in Neuroscience 13, 485010, 2019
1052019
Amyloid β (1-42) oligomers, derivatives thereof and antibodies thereto, methods of preparation thereof and use thereof
H Hillen, A Striebinger
US Patent 7,902,328, 2011
782011
Two‐dimensional analysis of myocardial protein expression following myocardial ischemia and reperfusion in rabbits
H Schwertz, T Längin, H Platsch, J Richert, S Bomm, M Schmidt, H Hillen, ...
Proteomics 2 (8), 988-995, 2002
772002
Monomeric structures of the zymogen and active catalytic domain of complement protease c1r: further insights into the c1 activation mechanism
M Budayova-Spano, W Grabarse, NM Thielens, H Hillen, M Lacroix, ...
Structure 10 (11), 1509-1519, 2002
692002
Anti-Aβ globulomer 5F7 antibodies
S Barghorn, H Hillen, B Labkovsky, AR Striebinger, P Keller, U Ebert
US Patent 8,691,224, 2014
612014
Humanized antibodies to ab (20-42) globulomer and uses thereof
S Barghorn, U Ebert, H Hillen, P Keller, AR Striebinger, B Labkovsky, ...
US Patent App. 12/129,469, 2009
592009
Screening Method, Process for Purifying of Non-Diffusible A-Beta Oligomers, Selective Antibodies Against Said Non-Diffusible a-Beta Oligomers and a Process for Manufacturing of …
H Hillen, A Striebinger, P Keller, S Barghorn, U Ebert
US Patent App. 11/885,362, 2009
592009
Humanized Antibodies Which Bind To AB (1-42) Globulomer And Uses Thereof
H Hillen, S Barghorn, U Ebert, AR Striebinger, P Keller, B Labkovsky, ...
US Patent App. 12/129,395, 2009
532009
Pharmaceutical proteins
D Blohm, C Bollschweiler, H Hillen
Angewandte Chemie International Edition in English 27 (2), 207-225, 1988
501988
Immunotherapy alleviates amyloid-associated synaptic pathology in an Alzheimer’s disease mouse model
MM Dorostkar, S Burgold, S Filser, S Barghorn, B Schmidt, UR Anumala, ...
Brain 137 (12), 3319-3326, 2014
482014
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