Ras pathway activation in hepatocellular carcinoma and anti-tumoral effect of combined sorafenib and rapamycin in vivo P Newell, S Toffanin, A Villanueva, DY Chiang, B Minguez, L Cabellos, ... Journal of hepatology 51 (4), 725-733, 2009 | 273 | 2009 |
The hepatic apelin system: a new therapeutic target for liver disease A Principe, P Melgar‐Lesmes, G Fernández‐Varo, LR del Arbol, J Ros, ... Hepatology 48 (4), 1193-1201, 2008 | 174 | 2008 |
Pulsatility and high shear stress deteriorate barrier phenotype in brain microvascular endothelium F Garcia-Polite, J Martorell, P Del Rey-Puech, P Melgar-Lesmes, ... Journal of Cerebral Blood Flow & Metabolism 37 (7), 2614-2625, 2017 | 116 | 2017 |
Apelin mediates the induction of profibrogenic genes in human hepatic stellate cells P Melgar-Lesmes, G Casals, M Pauta, J Ros, V Reichenbach, R Bataller, ... Endocrinology 151 (11), 5306-5314, 2010 | 86 | 2010 |
Hypoxia and proinflammatory factors upregulate apelin receptor expression in human stellate cells and hepatocytes P Melgar-Lesmes, M Pauta, V Reichenbach, G Casals, J Ros, R Bataller, ... Gut 60 (10), 1404-1411, 2011 | 84 | 2011 |
Optimizing glutaraldehyde-fixed tissue heart valves with chondroitin sulfate hydrogel for endothelialization and shielding against deterioration M Lopez-Moya, P Melgar-Lesmes, K Kolandaivelu, ... Biomacromolecules 19 (4), 1234-1244, 2018 | 83 | 2018 |
Prevention of fibrosis progression in CCl4-treated rats: role of the hepatic endocannabinoid and apelin systems V Reichenbach, J Ros, G Fernandez-Varo, G Casals, P Melgar-Lesmes, ... Journal of Pharmacology and Experimental Therapeutics 340 (3), 629-637, 2012 | 77 | 2012 |
Monocyte-endothelial cell interactions in the regulation of vascular sprouting and liver regeneration in mouse P Melgar-Lesmes, ER Edelman Journal of hepatology 63 (4), 917-925, 2015 | 74 | 2015 |
Extent of flow recirculation governs expression of atherosclerotic and thrombotic biomarkers in arterial bifurcations J Martorell, P Santoma, K Kolandaivelu, VB Kolachalama, ... Cardiovascular research 103 (1), 37-46, 2014 | 64 | 2014 |
Multifunctional polyurethane–urea nanoparticles to target and arrest inflamed vascular environment: A potential tool for cancer therapy and diagnosis G Morral-Ruiz, P Melgar-Lesmes, C Solans, MJ García-Celma Journal of controlled release 171 (2), 163-171, 2013 | 63 | 2013 |
Treatment with chondroitin sulfate to modulate inflammation and atherogenesis in obesity P Melgar-Lesmes, F Garcia-Polite, P Del-Rey-Puech, E Rosas, ... Atherosclerosis 245, 82-87, 2016 | 60 | 2016 |
Vascular endothelial growth factor and angiopoietin-2 play a major role in the pathogenesis of vascular leakage in cirrhotic rats P Melgar-Lesmes, S Tugues, J Ros, G Fernandez-Varo, M Morales-Ruiz, ... Gut 58 (2), 285-292, 2009 | 59 | 2009 |
Increased nitric oxide production in lymphatic endothelial cells causes impairment of lymphatic drainage in cirrhotic rats J Ribera, M Pauta, P Melgar-Lesmes, S Tugues, G Fernández-Varo, ... Gut 62 (1), 138-145, 2013 | 56 | 2013 |
A small population of liver endothelial cells undergoes endothelial-to-mesenchymal transition in response to chronic liver injury J Ribera, M Pauta, P Melgar-Lesmes, B Córdoba, A Bosch, M Calvo, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 313 (5 …, 2017 | 52 | 2017 |
Graphene–dendrimer nanostars for targeted macrophage overexpression of metalloproteinase 9 and hepatic fibrosis precision therapy P Melgar-Lesmes, A Luquero, M Parra-Robert, A Mora, J Ribera, ... Nano letters 18 (9), 5839-5845, 2018 | 48 | 2018 |
Overexpression of angiopoietin‐2 in rats and patients with liver fibrosis. Therapeutic consequences of its inhibition M Pauta, J Ribera, P Melgar‐Lesmes, G Casals, J Rodríguez‐Vita, ... Liver International 35 (4), 1383-1392, 2015 | 42 | 2015 |
Chondroitin sulphate attenuates atherosclerosis in ApoE knockout mice involving cellular regulation of the inflammatory response P Melgar-Lesmes, A Sánchez-Herrero, F Lozano-Juan, ... Thrombosis and haemostasis 118 (07), 1329-1339, 2018 | 37 | 2018 |
Cerium oxide nanoparticles protect against oxidant injury and interfere with oxidative mediated kinase signaling in human-derived hepatocytes S Carvajal, M Perramón, G Casals, D Oró, J Ribera, M Morales-Ruiz, ... International journal of molecular sciences 20 (23), 5959, 2019 | 36 | 2019 |
Roles of the hepatic endocannabinoid and apelin systems in the pathogenesis of liver fibrosis P Melgar-Lesmes, M Perramon, W Jiménez Cells 8 (11), 1311, 2019 | 35 | 2019 |
Adenoviral dominant-negative soluble PDGFRβ improves hepatic collagen, systemic hemodynamics, and portal pressure in fibrotic rats V Reichenbach, G Fernández-Varo, G Casals, D Oró, J Ros, ... Journal of hepatology 57 (5), 967-973, 2012 | 33 | 2012 |