| Information integration and energy expenditure in gene regulation J Estrada, F Wong, A DePace, J Gunawardena Cell 166 (1), 234-244, 2016 | 148 | 2016 |
| Krüppel expression levels are maintained through compensatory evolution of shadow enhancers Z Wunderlich, MDJ Bragdon, BJ Vincent, JA White, J Estrada, AH DePace Cell reports 12 (11), 1740-1747, 2015 | 66 | 2015 |
| Dissecting the sharp response of a canonical developmental enhancer reveals multiple sources of cooperativity J Park, J Estrada, G Johnson, BJ Vincent, C Ricci-Tam, MDJ Bragdon, ... Elife 8, e41266, 2019 | 61 | 2019 |
| Shadow enhancers enable Hunchback bifunctionality in the Drosophila embryo MV Staller, BJ Vincent, MDJ Bragdon, T Lydiard-Martin, Z Wunderlich, ... Proceedings of the National Academy of Sciences 112 (3), 785-790, 2015 | 55 | 2015 |
| The appeasement of Doug: a synthetic approach to enhancer biology BJ Vincent, J Estrada, AH DePace Integrative Biology 8 (4), 475-484, 2016 | 51 | 2016 |
| SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms Y Wang, M Mohseni, A Grauel, JE Diez, W Guan, S Liang, JE Choi, M Pu, ... Scientific reports 11 (1), 1399, 2021 | 46 | 2021 |
| Yearly planning meetings: individualized development plans aren’t just more paperwork BJ Vincent, C Scholes, MV Staller, Z Wunderlich, J Estrada, J Park, ... Molecular cell 58 (5), 718-721, 2015 | 31 | 2015 |
| Hunchback is counter-repressed to regulate even-skipped stripe 2 expression in Drosophila embryos BJ Vincent, MV Staller, F Lopez-Rivera, MDJ Bragdon, ECG Pym, ... PLoS genetics 14 (9), e1007644, 2018 | 30 | 2018 |
| A gene expression atlas of a bicoid-depleted Drosophila embryo reveals early canalization of cell fate MV Staller, CC Fowlkes, MDJ Bragdon, Z Wunderlich, J Estrada, ... Development 142 (3), 587-596, 2015 | 27 | 2015 |
| SiteOut: an online tool to design binding site-free DNA sequences J Estrada, T Ruiz-Herrero, C Scholes, Z Wunderlich, AH DePace PloS one 11 (3), e0151740, 2016 | 21 | 2016 |
| A tunable coarse-grained model for ligand-receptor interaction T Ruiz-Herrero, J Estrada, R Guantes, DG Miguez PLoS computational biology 9 (11), e1003274, 2013 | 21 | 2013 |
| Trade-offs and noise tolerance in signal detection by genetic circuits R Guantes, J Estrada, JF Poyatos PLoS One 5 (8), e12314, 2010 | 20 | 2010 |
| Quantitative measurement and thermodynamic modeling of fused enhancers support a two-tiered mechanism for interpreting regulatory DNA MAH Samee, T Lydiard-Martin, KM Biette, BJ Vincent, MD Bragdon, ... Cell reports 21 (1), 236-245, 2017 | 13 | 2017 |
| A Mutation in the Drosophila melanogaster eve Stripe 2 Minimal Enhancer Is Buffered by Flanking Sequences F López-Rivera, OK Foster Rhoades, BJ Vincent, ECG Pym, ... G3: Genes, Genomes, Genetics 10 (12), 4473-4482, 2020 | 12 | 2020 |
| Cellular interrogation: exploiting cell-to-cell variability to discriminate regulatory mechanisms in oscillatory signalling J Estrada, N Andrew, D Gibson, F Chang, F Gnad, J Gunawardena PLoS computational biology 12 (7), e1004995, 2016 | 9 | 2016 |
| Proteus: a web-based, context-specific modelling tool for molecular networks F Gnad, J Estrada, J Gunawardena Bioinformatics 28 (9), 1284-1286, 2012 | 5 | 2012 |
| Dynamic and structural constraints in signal propagation by regulatory networks J Estrada, R Guantes Molecular BioSystems 9 (2), 268-284, 2013 | 4 | 2013 |
| Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance JL Cotton, J Estrada Diez, V Sagar, J Chen, M Piquet, J Alford, Y Song, ... Cancer Research 83 (21), 3611-3623, 2023 | 1 | 2023 |
| BINDING SITE-DEPLETED DNA FOR QUANTITATIVE STUDIES OF ENHANCER AND TF FUNCTION J Estrada, T Ruiz-Herrero, C Scholes, Z Wunderlich, AH DePace Integrating Regulatory Information in Eukaryotic Transcription, 69, 2020 | | 2020 |
| Caudal counter-represses Hunchback to regulate even-skipped stripe 2 expression in Drosophila embryos BJ Vincent, MV Staller, F Lopez-Rivera, MDJ Bragdon, Z Wunderlich, ... bioRxiv, 226373, 2017 | | 2017 |
Angela DePaceAssociate Professor of Systems Biology, Harvard Medical SchoolDirección de correo verificada de hms.harvard.edu
