A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic T Shapira, IA Monreal, SP Dion, DW Buchholz, B Imbiakha, AD Olmstead, ... Nature 605 (7909), 340-348, 2022 | 136 | 2022 |
Regenerative intestinal stem cells induced by acute and chronic injury: the saving grace of the epithelium? WD Rees, R Tandun, E Yau, NC Zachos, TS Steiner Frontiers in Cell and Developmental Biology 8, 583919, 2020 | 59 | 2020 |
Enteroids derived from inflammatory bowel disease patients display dysregulated endoplasmic reticulum stress pathways, leading to differential inflammatory responses and … WD Rees, M Stahl, K Jacobson, B Bressler, LM Sly, BA Vallance, ... Journal of Crohn's and Colitis 14 (7), 948-961, 2020 | 41 | 2020 |
Adaptive immune response to Clostridium difficile infection: A perspective for prevention and therapy WD Rees, TS Steiner European journal of immunology 48 (3), 398-406, 2018 | 39 | 2018 |
A novel highly potent inhibitor of TMPRSS2-like proteases blocks SARS-CoV-2 variants of concern and is broadly protective against infection and mortality in mice T Shapira, IA Monreal, SP Dion, M Jager, A Désilets, AD Olmstead, ... bioRxiv, 2021.05. 03.442520, 2021 | 18 | 2021 |
Flagellin-specific human CAR Tregs for immune regulation in IBD DA Boardman, MQ Wong, WD Rees, D Wu, ME Himmel, PC Orban, ... Journal of autoimmunity 134, 102961, 2023 | 15 | 2023 |
Fecal microbiota transplantation for recurrent Clostridioides difficile infection enhances adaptive immunity to C difficile toxin B L Cook, WD Rees, MQ Wong, H Peters, MK Levings, TS Steiner Gastroenterology 160 (6), 2155-2158. e4, 2021 | 14 | 2021 |
How do immune and mesenchymal cells influence the intestinal epithelial cell compartment in inflammatory bowel disease? Let’s crosstalk about it! WD Rees, LM Sly, TS Steiner Journal of Leucocyte Biology 108 (1), 309-321, 2020 | 14 | 2020 |
Recurrent Clostridioides difficile infection is associated with impaired T helper type 17 immunity to C difficile toxin B L Cook, WD Rees, MQ Wong, WW Kwok, MK Levings, TS Steiner Gastroenterology 160 (4), 1410-1413. e4, 2021 | 12 | 2021 |
Mycobacterium avium Subspecies paratuberculosis Infects and Replicates within Human Monocyte-Derived Dendritic Cells WD Rees, AC Lorenzo-Leal, TS Steiner, H Bach Microorganisms 8 (7), 994, 2020 | 11 | 2020 |
An in vitro chronic damage model impairs inflammatory and regenerative responses in human colonoid monolayers WD Rees, N Telkar, DTS Lin, MQ Wong, C Poloni, A Fathi, M Kobor, ... Cell reports 38 (3), 2022 | 9 | 2022 |
Identification of peptide sequences that selectively bind to pentaerythritol trinitrate hemisuccinate‐a surrogate of PETN, via phage display technology G Kubas, W Rees, J Caguiat, D Asch, D Fagan, P Cortes Peptide Science 108 (2), e22997, 2017 | 7 | 2017 |
Inhibition of glycogen synthase kinase-3-beta (GSK3β) blocks nucleocapsid phosphorylation and SARS-CoV-2 replication T Shapira, S Vimalanathan, C Rens, V Pichler, S Peña-Díaz, G Jordana, ... Molecular Biomedicine 3 (1), 43, 2022 | 6 | 2022 |
Impaired Th17 immunity in recurrent C. difficile infection is ameliorated by fecal microbial transplantation L Cook, WD Rees, MQ Wong, X Wang, H Peters, L Oliveira, T Lau, R Mah, ... medRxiv, 2020.06. 05.20114876, 2020 | 1 | 2020 |
A202 DYSREGULATED ENDOPLASMIC RETICULUM STRESS PATHWAYS IN COLON-DERIVED ENTEROIDS FROM INFLAMMATORY BOWEL DISEASE PATIENTS DRIVE DC MATURATION LEADING TO A PRO-INFLAMMATORY … WD Rees, M Stahl, K Jacobson, B Bressler, LM Sly, B Vallance, T Steiner Journal of the Canadian Association of Gastroenterology 3 (Suppl 1), 75, 2020 | | 2020 |
A41 ENDOPLASMIC RETICULUM STRESSED HUMAN COLON ORGANOIDS CONDITION DENDRITIC CELLS TO A PRO-INFLAMMATORY PHENOTYPE WD Rees, T Steiner, B Vallance, M Stahl, K Jacobson Journal of the Canadian Association of Gastroenterology 2 (Supplement_2), 82-83, 2019 | | 2019 |
CD4+ T Cells Specific for C. difficile Toxins are a Marker of Patients with Active Relapsing Disease L Cook, M Wong, W Rees, T Lau, M Levings, T Steiner Open Forum Infectious Diseases 4 (Suppl 1), S383, 2017 | | 2017 |