| MAFG-driven astrocytes promote CNS inflammation MA Wheeler, IC Clark, EC Tjon, Z Li, SEJ Zandee, CP Couturier, ... Nature 578 (7796), 593-599, 2020 | 327 | 2020 |
| Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes LM Sanmarco, MA Wheeler, C Gutiérrez-Vázquez, CM Polonio, ... Nature 590 (7846), 473-479, 2021 | 203 | 2021 |
| Barcoded viral tracing of single-cell interactions in central nervous system inflammation IC Clark, C Gutiérrez-Vázquez, MA Wheeler, Z Li, V Rothhammer, ... Science 372 (6540), eabf1230, 2021 | 155 | 2021 |
| Metabolic control of astrocyte pathogenic activity via cPLA2-MAVS CC Chao, C Gutiérrez-Vázquez, V Rothhammer, L Mayo, MA Wheeler, ... Cell 179 (7), 1483-1498. e22, 2019 | 141 | 2019 |
| Self-tunable engineered yeast probiotics for the treatment of inflammatory bowel disease BM Scott, C Gutierrez-Vazquez, LM Sanmarco, JA da Silva Pereira, Z Li, ... Nature medicine 27 (7), 1212-1222, 2021 | 137 | 2021 |
| Pro-inflammatory monocyte profile in patients with major depressive disorder and suicide behaviour and how ketamine induces anti-inflammatory M2 macrophages by NMDAR and mTOR W Nowak, LN Grendas, LM Sanmarco, IG Estecho, ÁR Arena, ... EBioMedicine 50, 290-305, 2019 | 110 | 2019 |
| IL-6 promotes M2 macrophage polarization by modulating purinergic signaling and regulates the lethal release of nitric oxide during Trypanosoma cruzi infection LM Sanmarco, NE Ponce, LM Visconti, N Eberhardt, MG Theumer, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (4), 857-869, 2017 | 93 | 2017 |
| AHR is a Zika virus host factor and a candidate target for antiviral therapy F Giovannoni, I Bosch, CM Polonio, MF Torti, MA Wheeler, Z Li, ... Nature Neuroscience 23 (8), 939-951, 2020 | 77 | 2020 |
| Functional immune cell–astrocyte interactions LM Sanmarco, CM Polonio, MA Wheeler, FJ Quintana Journal of Experimental Medicine 218 (9), e20202715, 2021 | 67 | 2021 |
| New insights into the immunobiology of mononuclear phagocytic cells and their relevance to the pathogenesis of cardiovascular diseases LM Sanmarco, N Eberhardt, NE Ponce, RC Cano, G Bonacci, MP Aoki Frontiers in immunology 8, 311582, 2018 | 53 | 2018 |
| Identification of environmental factors that promote intestinal inflammation LM Sanmarco, CC Chao, YC Wang, JE Kenison, Z Li, JM Rone, ... Nature 611 (7937), 801-809, 2022 | 51 | 2022 |
| Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a … ME Cabalén, MF Cabral, LM Sanmarco, MC Andrada, LI Onofrio, ... Oncotarget 7 (12), 13400, 2016 | 51 | 2016 |
| Droplet-based forward genetic screening of astrocyte–microglia cross-talk MA Wheeler, IC Clark, HG Lee, Z Li, M Linnerbauer, JM Rone, M Blain, ... Science 379 (6636), 1023-1030, 2023 | 42 | 2023 |
| CD73 inhibition shifts cardiac macrophage polarization toward a microbicidal phenotype and ameliorates the outcome of experimental Chagas cardiomyopathy NE Ponce, LM Sanmarco, N Eberhardt, MC García, HW Rivarola, ... The Journal of Immunology 197 (3), 814-823, 2016 | 40 | 2016 |
| IL-6 improves the nitric oxide-induced cytotoxic CD8+ T cell dysfunction in human Chagas disease LM Sanmarco, LM Visconti, N Eberhardt, MC Ramello, NE Ponce, ... Frontiers in immunology 7, 626, 2016 | 38 | 2016 |
| Clomipramine and benznidazole act synergistically and ameliorate the outcome of experimental Chagas disease MC García, NE Ponce, LM Sanmarco, RH Manzo, AF Jimenez-Kairuz, ... Antimicrobial agents and chemotherapy 60 (6), 3700-3708, 2016 | 29 | 2016 |
| Multi-kinetic release of benznidazole-loaded multiparticulate drug delivery systems based on polymethacrylate interpolyelectrolyte complexes MC García, M Martinelli, NE Ponce, LM Sanmarco, MP Aoki, RH Manzo, ... European Journal of Pharmaceutical Sciences 120, 107-122, 2018 | 25 | 2018 |
| Identification of astrocyte regulators by nucleic acid cytometry IC Clark, MA Wheeler, HG Lee, Z Li, LM Sanmarco, S Thaploo, ... Nature 614 (7947), 326-333, 2023 | 24 | 2023 |
| Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells LM Sanmarco, JM Rone, CM Polonio, G Fernandez Lahore, F Giovannoni, ... Nature 620 (7975), 881-889, 2023 | 19 | 2023 |
| Monocyte glycolysis determines CD8+ T cell functionality in human Chagas disease LM Sanmarco, N Eberhardt, G Bergero, LPQ Palacio, PM Adami, ... JCI insight 4 (18), 2019 | 16 | 2019 |
Michael WheelerAssistant Professor, Harvard Medical School, Brigham & Women's HospitalVerified email at bwh.harvard.edu
